ID ASA1_CANAL Reviewed; 377 AA.
AC Q5ABV4; A0A1D8PQ30; Q5AC76;
DT 30-NOV-2010, integrated into UniProtKB/Swiss-Prot.
DT 12-APR-2017, sequence version 2.
DT 08-NOV-2023, entry version 109.
DE RecName: Full=ASTRA-associated protein 1;
GN Name=ASA1; OrderedLocusNames=CAALFM_C603110CA;
GN ORFNames=CaO19.13041, CaO19.5596;
OS Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX NCBI_TaxID=237561;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SC5314 / ATCC MYA-2876;
RX PubMed=15123810; DOI=10.1073/pnas.0401648101;
RA Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B.,
RA Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W.,
RA Scherer S.;
RT "The diploid genome sequence of Candida albicans.";
RL Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=SC5314 / ATCC MYA-2876;
RX PubMed=17419877; DOI=10.1186/gb-2007-8-4-r52;
RA van het Hoog M., Rast T.J., Martchenko M., Grindle S., Dignard D.,
RA Hogues H., Cuomo C., Berriman M., Scherer S., Magee B.B., Whiteway M.,
RA Chibana H., Nantel A., Magee P.T.;
RT "Assembly of the Candida albicans genome into sixteen supercontigs aligned
RT on the eight chromosomes.";
RL Genome Biol. 8:RESEARCH52.1-RESEARCH52.12(2007).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC STRAIN=SC5314 / ATCC MYA-2876;
RX PubMed=24025428; DOI=10.1186/gb-2013-14-9-r97;
RA Muzzey D., Schwartz K., Weissman J.S., Sherlock G.;
RT "Assembly of a phased diploid Candida albicans genome facilitates allele-
RT specific measurements and provides a simple model for repeat and indel
RT structure.";
RL Genome Biol. 14:RESEARCH97.1-RESEARCH97.14(2013).
CC -!- FUNCTION: Component of the ASTRA complex involved in chromatin
CC remodeling. {ECO:0000250}.
CC -!- SUBUNIT: Component of the ASTRA chromatin remodeling machinery complex.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the WD repeat ASA1 family. {ECO:0000305}.
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DR EMBL; CP017628; AOW30242.1; -; Genomic_DNA.
DR RefSeq; XP_719157.2; XM_714064.2.
DR AlphaFoldDB; Q5ABV4; -.
DR SMR; Q5ABV4; -.
DR STRING; 237561.Q5ABV4; -.
DR EnsemblFungi; C6_03110C_A-T; C6_03110C_A-T-p1; C6_03110C_A.
DR GeneID; 3639278; -.
DR KEGG; cal:CAALFM_C603110CA; -.
DR CGD; CAL0000191787; orf19.13041.
DR VEuPathDB; FungiDB:C6_03110C_A; -.
DR eggNOG; KOG0322; Eukaryota.
DR HOGENOM; CLU_045414_0_0_1; -.
DR InParanoid; Q5ABV4; -.
DR OrthoDB; 5476119at2759; -.
DR PRO; PR:Q5ABV4; -.
DR Proteomes; UP000000559; Chromosome 6.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-KW.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR SMART; SM00320; WD40; 3.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 1.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 3: Inferred from homology;
KW Chromatin regulator; Nucleus; Reference proteome; Repeat; WD repeat.
FT CHAIN 1..377
FT /note="ASTRA-associated protein 1"
FT /id="PRO_0000402204"
FT REPEAT 10..50
FT /note="WD 1"
FT REPEAT 53..90
FT /note="WD 2"
FT REPEAT 230..262
FT /note="WD 3"
FT REPEAT 263..303
FT /note="WD 4"
FT REPEAT 342..377
FT /note="WD 5"
SQ SEQUENCE 377 AA; 42568 MW; 44F05259226280D9 CRC64;
MLSTKFTLRS HKSSVAYIYQ DPRTPFNLFT ADSSGLIINW DLTIRRPKKS WQAHTDTILT
ISTIHNHLLT HSRDNTIKIW DESYSCVLEI PCNALNFSNI CIIYDLLITP ASINSNNLDV
YKIDKDWQIT RLISDFDVYK LVNKGEIIEE IGSSGTSRND FGIIMQMKII HTNTTTTTSE
NNSDYIIYVG FESGDIVGLQ LILPRARILS TTGNTNDKTL INQSAKFILQ YHNSTHVPNP
VICLSNLDSV LVSGSTTNKV IIHSDPIEIM KMDHSGIQAI VNFKNDRLIF GYWNGYIQYG
DISINQSLPK LGNTEQEKSK LTKKLTFMTI LNESNQETLQ SPTGKSKYLA LLKSKRNLVF
PLLLAGYEDG SILAYNI
//
