ID B0A661_9FIRM Unreviewed; 746 AA.
AC B0A661;
DT 26-FEB-2008, integrated into UniProtKB/TrEMBL.
DT 26-FEB-2008, sequence version 1.
DT 27-MAR-2024, entry version 67.
DE SubName: Full=Beta-galactosidase/beta-glucuronidase {ECO:0000313|EMBL:SKA62939.1};
GN ORFNames=SAMN02745147_0118 {ECO:0000313|EMBL:SKA62939.1};
OS Intestinibacter bartlettii DSM 16795.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Peptostreptococcaceae;
OC Intestinibacter.
OX NCBI_TaxID=445973 {ECO:0000313|EMBL:SKA62939.1, ECO:0000313|Proteomes:UP000190760};
RN [1] {ECO:0000313|EMBL:SKA62939.1, ECO:0000313|Proteomes:UP000190760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 16795 {ECO:0000313|EMBL:SKA62939.1,
RC ECO:0000313|Proteomes:UP000190760};
RA Peterson S.W.;
RL Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 2 family.
CC {ECO:0000256|ARBA:ARBA00007401}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FUXV01000011; SKA62939.1; -; Genomic_DNA.
DR RefSeq; WP_007285238.1; NZ_FUXV01000011.1.
DR AlphaFoldDB; B0A661; -.
DR STRING; 261299.ERS852493_02647; -.
DR eggNOG; COG3250; Bacteria.
DR OrthoDB; 9762066at2; -.
DR Proteomes; UP000190760; Unassembled WGS sequence.
DR GO; GO:0004565; F:beta-galactosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR InterPro; IPR036156; Beta-gal/glucu_dom_sf.
DR InterPro; IPR032311; DUF4982.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR006101; Glyco_hydro_2.
DR InterPro; IPR006103; Glyco_hydro_2_cat.
DR InterPro; IPR006102; Glyco_hydro_2_Ig-like.
DR InterPro; IPR006104; Glyco_hydro_2_N.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR PANTHER; PTHR42732; BETA-GALACTOSIDASE; 1.
DR PANTHER; PTHR42732:SF1; BETA-MANNOSIDASE; 1.
DR Pfam; PF16355; DUF4982; 1.
DR Pfam; PF00703; Glyco_hydro_2; 1.
DR Pfam; PF02836; Glyco_hydro_2_C; 1.
DR Pfam; PF02837; Glyco_hydro_2_N; 1.
DR PRINTS; PR00132; GLHYDRLASE2.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49303; beta-Galactosidase/glucuronidase domain; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801}.
FT DOMAIN 6..146
FT /note="Glycosyl hydrolases family 2 sugar binding"
FT /evidence="ECO:0000259|Pfam:PF02837"
FT DOMAIN 164..258
FT /note="Glycoside hydrolase family 2 immunoglobulin-like
FT beta-sandwich"
FT /evidence="ECO:0000259|Pfam:PF00703"
FT DOMAIN 266..547
FT /note="Glycoside hydrolase family 2 catalytic"
FT /evidence="ECO:0000259|Pfam:PF02836"
FT DOMAIN 573..619
FT /note="DUF4982"
FT /evidence="ECO:0000259|Pfam:PF16355"
SQ SEQUENCE 746 AA; 85920 MW; 70056A2E775DBB9D CRC64;
MRQIYNFNTK WGFSKEALEA PTTMPERWNW VNIPHTWNNI DGQDGGNDLY RGTAFYAKEL
EKMDLPKADR YFLEIQGANS SAILYVNGKK LANHDGGYST WRVDITDALE DKNLFVFEVD
NSQNDRVYPQ NADFTFYGGI YRDLNIIAVS ESHFDLEYYG TPGIKVTPEV VGKDAKVEVE
VFVKNEKETQ KLVYTLKDAE GNVVAEKETP ASETVASFEI ENVHLWHGKK DPYLYTAEVC
LKYEEEVLDN VSARFGCRTF EIHPENGFIL NGEEYPLRGV SRHQDRWGIG NELLKEHHDE
DMDLICELGA TTIRLAHYQH DQYFYDLCDE RGMVVWAEIP YISTHMPNGR ENTISQMKEL
VVQNYNHPSI IVWGLSNEIT MHGDSDEDLR ENHVILNDLV HEMDKTRLTT MACVSMCSMD
DPYVQIPDTV SYNHYFGWYG GDTSQNGPWF DEFHAKYPNI PIGCSEYGCE ALNWHTSDPQ
QGDYTEEYQA YYHEELIKQF YTRKYMWATH VWNMFDFGAD SRNEGGENGQ NHKGLITFDR
KYKKDSFYAY KAWLSDEPFV HICGKRYVDR VEETTKVTVY SNQPEVELFA NGVSLGKQTC
PEHFFYFEVP NTGETTLVAV AGDCKDESFI RKVEVFNEEY RLKEKGAILN WFDVTAPEEY
YSLNSKIEDI VKSEEGATVF KEVMVSAMGS MMGGNSEKFD MAPMMKMLGS FTVLRLTSLL
GATNVNLTKE QLLDMNEKLN AIPVVE
//
