ID B0AD20_9FIRM Unreviewed; 312 AA.
AC B0AD20;
DT 26-FEB-2008, integrated into UniProtKB/TrEMBL.
DT 26-FEB-2008, sequence version 1.
DT 24-JAN-2024, entry version 51.
DE RecName: Full=UTP--glucose-1-phosphate uridylyltransferase {ECO:0000256|ARBA:ARBA00012415, ECO:0000256|RuleBase:RU361259};
DE EC=2.7.7.9 {ECO:0000256|ARBA:ARBA00012415, ECO:0000256|RuleBase:RU361259};
DE AltName: Full=UDP-glucose pyrophosphorylase {ECO:0000256|RuleBase:RU361259};
GN ORFNames=SAMN02745147_0033 {ECO:0000313|EMBL:SKA62061.1};
OS Intestinibacter bartlettii DSM 16795.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Peptostreptococcaceae;
OC Intestinibacter.
OX NCBI_TaxID=445973 {ECO:0000313|EMBL:SKA62061.1, ECO:0000313|Proteomes:UP000190760};
RN [1] {ECO:0000313|EMBL:SKA62061.1, ECO:0000313|Proteomes:UP000190760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 16795 {ECO:0000313|EMBL:SKA62061.1,
RC ECO:0000313|Proteomes:UP000190760};
RA Peterson S.W.;
RL Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=alpha-D-glucose 1-phosphate + H(+) + UTP = diphosphate + UDP-
CC alpha-D-glucose; Xref=Rhea:RHEA:19889, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:33019, ChEBI:CHEBI:46398, ChEBI:CHEBI:58601,
CC ChEBI:CHEBI:58885; EC=2.7.7.9;
CC Evidence={ECO:0000256|ARBA:ARBA00000872,
CC ECO:0000256|RuleBase:RU361259};
CC -!- SIMILARITY: Belongs to the UDPGP type 2 family.
CC {ECO:0000256|ARBA:ARBA00006890, ECO:0000256|RuleBase:RU361259}.
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DR EMBL; FUXV01000010; SKA62061.1; -; Genomic_DNA.
DR RefSeq; WP_007287623.1; NZ_FUXV01000010.1.
DR AlphaFoldDB; B0AD20; -.
DR STRING; 261299.ERS852493_02553; -.
DR GeneID; 68215865; -.
DR eggNOG; COG1210; Bacteria.
DR OrthoDB; 9803871at2; -.
DR Proteomes; UP000190760; Unassembled WGS sequence.
DR GO; GO:0003983; F:UTP:glucose-1-phosphate uridylyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR GO; GO:0006011; P:UDP-glucose metabolic process; IEA:InterPro.
DR CDD; cd02541; UGPase_prokaryotic; 1.
DR InterPro; IPR005771; GalU_uridylyltTrfase_bac/arc.
DR InterPro; IPR005835; NTP_transferase_dom.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR NCBIfam; TIGR01099; galU; 1.
DR PANTHER; PTHR43197; UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE; 1.
DR PANTHER; PTHR43197:SF1; UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE; 1.
DR Pfam; PF00483; NTP_transferase; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE 3: Inferred from homology;
KW Nucleotidyltransferase {ECO:0000256|RuleBase:RU361259,
KW ECO:0000313|EMBL:SKA62061.1};
KW Transferase {ECO:0000256|RuleBase:RU361259, ECO:0000313|EMBL:SKA62061.1}.
FT DOMAIN 7..268
FT /note="Nucleotidyl transferase"
FT /evidence="ECO:0000259|Pfam:PF00483"
SQ SEQUENCE 312 AA; 35181 MW; BA7020944FFF9810 CRC64;
MQKKIKKAVI PAAGLGTRFL PATKAQPKEM LPIVDKPTLQ YIIEEAVASG IEEILIITGK
NKKSIEDHFD KSVELELELE QKGKTELLEI VRDISQMVNI YYIRQKEPKG LGDAIYCARS
FIGDEPFAVM LGDDIVDNDV PCLKQLMSAY EEYRTTILGV QTVAPEDANK YGIINARYIE
DNVYKVKDLV EKPEPGKQPS NIAILGRYII TPEIFEILEN QAPGKGGEVQ LTDALKTLSK
KEAMYAYEFE GRRYDVGDKL GFLEATVDFA LKKPELKDSF MDYLKKVCKE TNIEKEVALT
EDSESKDKKV IK
//
