ID B0B5R6_CLOBO Unreviewed; 315 AA.
AC B0B5R6;
DT 26-FEB-2008, integrated into UniProtKB/TrEMBL.
DT 26-FEB-2008, sequence version 1.
DT 24-JAN-2024, entry version 55.
DE RecName: Full=argininosuccinate synthase {ECO:0000256|ARBA:ARBA00012286};
DE EC=6.3.4.5 {ECO:0000256|ARBA:ARBA00012286};
DE AltName: Full=Citrulline--aspartate ligase {ECO:0000256|ARBA:ARBA00029916};
DE Flags: Fragment;
GN Name=argG {ECO:0000313|EMBL:CAO86160.1};
GN ORFNames=CBO2670 {ECO:0000313|EMBL:CAO86160.1};
OS Clostridium botulinum.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1491 {ECO:0000313|EMBL:CAO86160.1};
RN [1] {ECO:0000313|EMBL:CAO86160.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NKH-50/1 {ECO:0000313|EMBL:CAO86160.1};
RA Lindstrom M., Hinderink K., Somervuo P., Kiviniemi K., Nevas M., Chen Y.,
RA Auvinen P., Carter A.T., Mason D.R., Peck M.W., Korkeala H.;
RT "Comparative Genomic Hybridization Analysis of Two Predominant Nordic Group
RT I (Proteolytic) Clostridium botulinum Type B Clusters.";
RL Appl. Environ. Microbiol. 75:2643-2651(2009).
CC -!- PATHWAY: Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine
CC from L-ornithine and carbamoyl phosphate: step 2/3.
CC {ECO:0000256|ARBA:ARBA00004967}.
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DR EMBL; AM774125; CAO86160.1; -; Genomic_DNA.
DR UniPathway; UPA00068; UER00113.
DR GO; GO:0004055; F:argininosuccinate synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-UniPathway.
DR CDD; cd01999; Argininosuccinate_Synthase; 1.
DR Gene3D; 3.90.1260.10; Argininosuccinate synthetase, chain A, domain 2; 1.
DR Gene3D; 3.40.50.620; HUPs; 1.
DR InterPro; IPR048268; Arginosuc_syn_C.
DR InterPro; IPR048267; Arginosuc_syn_N.
DR InterPro; IPR001518; Arginosuc_synth.
DR InterPro; IPR018223; Arginosuc_synth_CS.
DR InterPro; IPR023434; Arginosuc_synth_type_1_subfam.
DR InterPro; IPR024074; AS_cat/multimer_dom_body.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR NCBIfam; TIGR00032; argG; 1.
DR PANTHER; PTHR11587; ARGININOSUCCINATE SYNTHASE; 1.
DR PANTHER; PTHR11587:SF2; ARGININOSUCCINATE SYNTHASE; 1.
DR Pfam; PF20979; Arginosuc_syn_C; 1.
DR Pfam; PF00764; Arginosuc_synth; 1.
DR SUPFAM; SSF52402; Adenine nucleotide alpha hydrolases-like; 1.
DR SUPFAM; SSF69864; Argininosuccinate synthetase, C-terminal domain; 1.
DR PROSITE; PS00565; ARGININOSUCCIN_SYN_2; 1.
PE 4: Predicted;
KW Amino-acid biosynthesis {ECO:0000256|ARBA:ARBA00022605};
KW Arginine biosynthesis {ECO:0000256|ARBA:ARBA00022571};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 6..115
FT /note="Arginosuccinate synthase-like N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00764"
FT DOMAIN 124..314
FT /note="Arginosuccinate synthase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF20979"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:CAO86160.1"
FT NON_TER 315
FT /evidence="ECO:0000313|EMBL:CAO86160.1"
SQ SEQUENCE 315 AA; 35880 MW; DB25449FB7904070 CRC64;
KVSVHQKYXV EDVKEEFVVD YLYKAIKSEA LYEQDYMLGT SFARPLMAKK LVEIAHKEQA
KYICHGCTGK GNDQVRFEVG VKAQDPTIKI IAPWRIWDIK SREDAIDYAK KVGVEVPVTK
KKIYSVDRNL WHVSHEGGDL EDLKNEHKED MYFMVTPPEK AKDEPTYLEI YFKKGVPVKI
NGEFLNPVDI IDKLNTIGGE NGIGIADIIE NRLVGMKSRG IYETPAGTLL YAAHKKLESV
TLDKYTYQYK KLVSAQYGEL VYNGLWFTAL REAIDAFVDK TQENVTGTVK LKLYKGNIKP
CSVDTEYALY DEGIS
//
