ID B0C7N2_ACAM1 Unreviewed; 246 AA.
AC B0C7N2;
DT 26-FEB-2008, integrated into UniProtKB/TrEMBL.
DT 26-FEB-2008, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE RecName: Full=D-lactate dehydratase {ECO:0000256|ARBA:ARBA00013134};
DE EC=4.2.1.130 {ECO:0000256|ARBA:ARBA00013134};
GN OrderedLocusNames=AM1_0206 {ECO:0000313|EMBL:ABW25292.1};
OS Acaryochloris marina (strain MBIC 11017).
OC Bacteria; Cyanobacteriota; Cyanophyceae; Acaryochloridales;
OC Acaryochloridaceae; Acaryochloris.
OX NCBI_TaxID=329726 {ECO:0000313|EMBL:ABW25292.1, ECO:0000313|Proteomes:UP000000268};
RN [1] {ECO:0000313|EMBL:ABW25292.1, ECO:0000313|Proteomes:UP000000268}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MBIC 11017 {ECO:0000313|Proteomes:UP000000268};
RX PubMed=18252824; DOI=10.1073/pnas.0709772105;
RA Swingley W.D., Chen M., Cheung P.C., Conrad A.L., Dejesa L.C., Hao J.,
RA Honchak B.M., Karbach L.E., Kurdoglu A., Lahiri S., Mastrian S.D.,
RA Miyashita H., Page L., Ramakrishna P., Satoh S., Sattley W.M., Shimada Y.,
RA Taylor H.L., Tomo T., Tsuchiya T., Wang Z.T., Raymond J., Mimuro M.,
RA Blankenship R.E., Touchman J.W.;
RT "Niche adaptation and genome expansion in the chlorophyll d-producing
RT cyanobacterium Acaryochloris marina.";
RL Proc. Natl. Acad. Sci. U.S.A. 105:2005-2010(2008).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + methylglyoxal = (R)-lactate + H(+);
CC Xref=Rhea:RHEA:27754, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:16004, ChEBI:CHEBI:17158; EC=4.2.1.130;
CC Evidence={ECO:0000256|ARBA:ARBA00001524};
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DR EMBL; CP000828; ABW25292.1; -; Genomic_DNA.
DR AlphaFoldDB; B0C7N2; -.
DR STRING; 329726.AM1_0206; -.
DR KEGG; amr:AM1_0206; -.
DR eggNOG; COG0693; Bacteria.
DR HOGENOM; CLU_070319_1_1_3; -.
DR OrthoDB; 9792284at2; -.
DR Proteomes; UP000000268; Chromosome.
DR CDD; cd03141; GATase1_Hsp31_like; 1.
DR Gene3D; 3.40.50.880; -; 1.
DR InterPro; IPR029062; Class_I_gatase-like.
DR InterPro; IPR002818; DJ-1/PfpI.
DR PANTHER; PTHR48094:SF11; GLUTATHIONE-INDEPENDENT GLYOXALASE HSP31-RELATED; 1.
DR PANTHER; PTHR48094; PROTEIN/NUCLEIC ACID DEGLYCASE DJ-1-RELATED; 1.
DR Pfam; PF01965; DJ-1_PfpI; 1.
DR SUPFAM; SSF52317; Class I glutamine amidotransferase-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000000268};
KW Stress response {ECO:0000256|ARBA:ARBA00023016}.
FT DOMAIN 26..230
FT /note="DJ-1/PfpI"
FT /evidence="ECO:0000259|Pfam:PF01965"
SQ SEQUENCE 246 AA; 26614 MW; 87FEB49EB250F48E CRC64;
MSKHILMIVS NSATSNIGKP VGICAVELIH PYAVLKASGC QVTIASSQGG PIELDAQSEP
RDPSGFLSLD ILSARYITQA AFTDQLSNTP AISNLNTQDY DAIFVCGGQG TLYTFPKDKA
LTDLFVSFYQ DEKPSATLCR GACLLLNATL DNGEPLIQGK MITGFSKKEE QWMSKNFGPM
MVPFVVEEEA KKRGAKFVAS SAFTPFVIQD SNLITGQQSN SAFLTASLVL KALDLDFNDS
YFDNSH
//
