ID B0CM35_PAPAN Unreviewed; 140 AA.
AC B0CM35;
DT 26-FEB-2008, integrated into UniProtKB/TrEMBL.
DT 26-FEB-2008, sequence version 1.
DT 24-JAN-2024, entry version 67.
DE RecName: Full=Guided entry of tail-anchored proteins factor 1 {ECO:0000256|ARBA:ARBA00017951};
DE AltName: Full=Tail-anchored protein insertion receptor WRB {ECO:0000256|ARBA:ARBA00032437};
DE AltName: Full=Tryptophan-rich basic protein {ECO:0000256|ARBA:ARBA00033006};
GN Name=WRB {ECO:0000313|EMBL:ABY63627.1};
OS Papio anubis (Olive baboon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Papio.
OX NCBI_TaxID=9555 {ECO:0000313|EMBL:ABY63627.1};
RN [1] {ECO:0000313|EMBL:ABY63627.1}
RP NUCLEOTIDE SEQUENCE.
RA Antonellis A., Benjamin B., Blakesley R.W., Bouffard G.G., Brinkley C.,
RA Brooks S., Chu G., Chub I., Coleman H., Fuksenko T., Gestole M.,
RA Gregory M., Guan X., Gupta J., Gurson N., Han E., Han J., Hansen N.,
RA Hargrove A., Hines-Harris K., Ho S.-L., Hu P., Hunter G., Hurle B.,
RA Idol J.R., Johnson T., Knight E., Kwong P., Lee-Lin S.-Q., Legaspi R.,
RA Madden M., Maduro Q.L., Maduro V.B., Margulies E.H., Masiello C.,
RA Maskeri B., McDowell J., Merkulov G., Montemayor C., Mullikin J.C.,
RA Park M., Prasad A., Ramsahoye C., Reddix-Dugue N., Riebow N., Schandler K.,
RA Schueler M.G., Sison C., Smith L., Stantripop S., Thomas J.W., Thomas P.J.,
RA Tsipouri V., Young A., Green E.D.;
RT "NISC Comparative Sequencing Initiative.";
RL Submitted (JAN-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004477}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004477}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the WRB/GET1 family.
CC {ECO:0000256|ARBA:ARBA00010799}.
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DR EMBL; DP000537; ABY63627.1; -; Genomic_DNA.
DR RefSeq; NP_001162466.1; NM_001168995.1.
DR RefSeq; XP_009200505.1; XM_009202241.2.
DR AlphaFoldDB; B0CM35; -.
DR SMR; B0CM35; -.
DR GeneID; 100137464; -.
DR KEGG; panu:100137464; -.
DR CTD; 7485; -.
DR eggNOG; KOG4253; Eukaryota.
DR HOGENOM; CLU_121992_0_0_1; -.
DR OrthoDB; 2917135at2759; -.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0071816; P:tail-anchored membrane protein insertion into ER membrane; IEA:InterPro.
DR Gene3D; 1.10.287.660; Helix hairpin bin; 1.
DR InterPro; IPR028945; Get1.
DR InterPro; IPR029012; Helix_hairpin_bin_sf.
DR PANTHER; PTHR42650:SF1; GUIDED ENTRY OF TAIL-ANCHORED PROTEINS FACTOR 1; 1.
DR PANTHER; PTHR42650; TAIL-ANCHORED PROTEIN INSERTION RECEPTOR WRB; 1.
DR Pfam; PF04420; CHD5; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 68..90
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 115..136
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT COILED 5..58
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 140 AA; 16011 MW; 601B094EF9F52C95 CRC64;
MSRVLQKDAE QESQMRAEIQ DMKQELSTVN MMDEFARYAR LERKINKMTD KLKTHVKART
AQLAKIKWVI SVAFYVLQAA LMISLIWKYY SVPVAVVPSK WITPLDRLVA FPTRVAGGVG
ITCWILVCNK VVAIVLHPFS
//
