ID B0E106_LACBS Unreviewed; 705 AA.
AC B0E106;
DT 26-FEB-2008, integrated into UniProtKB/TrEMBL.
DT 26-FEB-2008, sequence version 1.
DT 27-MAR-2024, entry version 77.
DE SubName: Full=Histone deacetylase complex protein {ECO:0000313|EMBL:EDQ99497.1};
GN Name=HDA16207 {ECO:0000313|EMBL:EDQ99497.1};
GN ORFNames=LACBIDRAFT_316459 {ECO:0000313|EMBL:EDQ99497.1};
OS Laccaria bicolor (strain S238N-H82 / ATCC MYA-4686) (Bicoloured deceiver)
OS (Laccaria laccata var. bicolor).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Agaricineae; Hydnangiaceae; Laccaria.
OX NCBI_TaxID=486041 {ECO:0000313|Proteomes:UP000001194};
RN [1] {ECO:0000313|EMBL:EDQ99497.1, ECO:0000313|Proteomes:UP000001194}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S238N-H82 / ATCC MYA-4686 {ECO:0000313|Proteomes:UP000001194};
RX PubMed=18322534; DOI=10.1038/nature06556;
RA Martin F., Aerts A., Ahren D., Brun A., Danchin E.G.J., Duchaussoy F.,
RA Gibon J., Kohler A., Lindquist E., Pereda V., Salamov A., Shapiro H.J.,
RA Wuyts J., Blaudez D., Buee M., Brokstein P., Canbaeck B., Cohen D.,
RA Courty P.E., Coutinho P.M., Delaruelle C., Detter J.C., Deveau A.,
RA DiFazio S., Duplessis S., Fraissinet-Tachet L., Lucic E., Frey-Klett P.,
RA Fourrey C., Feussner I., Gay G., Grimwood J., Hoegger P.J., Jain P.,
RA Kilaru S., Labbe J., Lin Y.C., Legue V., Le Tacon F., Marmeisse R.,
RA Melayah D., Montanini B., Muratet M., Nehls U., Niculita-Hirzel H.,
RA Oudot-Le Secq M.P., Peter M., Quesneville H., Rajashekar B., Reich M.,
RA Rouhier N., Schmutz J., Yin T., Chalot M., Henrissat B., Kuees U.,
RA Lucas S., Van de Peer Y., Podila G.K., Polle A., Pukkila P.J.,
RA Richardson P.M., Rouze P., Sanders I.R., Stajich J.E., Tunlid A.,
RA Tuskan G., Grigoriev I.V.;
RT "The genome of Laccaria bicolor provides insights into mycorrhizal
RT symbiosis.";
RL Nature 452:88-92(2008).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; DS547163; EDQ99497.1; -; Genomic_DNA.
DR RefSeq; XP_001889846.1; XM_001889811.1.
DR AlphaFoldDB; B0E106; -.
DR STRING; 486041.B0E106; -.
DR GeneID; 6085476; -.
DR KEGG; lbc:LACBIDRAFT_316459; -.
DR HOGENOM; CLU_007727_4_3_1; -.
DR InParanoid; B0E106; -.
DR OrthoDB; 124800at2759; -.
DR Proteomes; UP000001194; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0010468; P:regulation of gene expression; IEA:UniProt.
DR Gene3D; 3.40.800.20; Histone deacetylase domain; 1.
DR InterPro; IPR019154; Arb2-like_domain.
DR InterPro; IPR000286; His_deacetylse.
DR InterPro; IPR023801; His_deacetylse_dom.
DR InterPro; IPR037138; His_deacetylse_dom_sf.
DR InterPro; IPR023696; Ureohydrolase_dom_sf.
DR PANTHER; PTHR10625:SF4; HISTONE DEACETYLASE 6, ISOFORM G; 1.
DR PANTHER; PTHR10625; HISTONE DEACETYLASE HDAC1-RELATED; 1.
DR Pfam; PF09757; Arb2; 1.
DR Pfam; PF00850; Hist_deacetyl; 2.
DR PRINTS; PR01270; HDASUPER.
DR SUPFAM; SSF52768; Arginase/deacetylase; 1.
PE 4: Predicted;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000001194}.
FT DOMAIN 64..304
FT /note="Histone deacetylase"
FT /evidence="ECO:0000259|Pfam:PF00850"
FT DOMAIN 317..382
FT /note="Histone deacetylase"
FT /evidence="ECO:0000259|Pfam:PF00850"
FT DOMAIN 438..688
FT /note="Arb2-like"
FT /evidence="ECO:0000259|Pfam:PF09757"
FT REGION 1..37
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 705 AA; 78523 MW; 80126A7AC947965D CRC64;
MEAYEAGPSE AMDVDQQPAQ TNGEFPAPVQ RGPRALSVPM KHPGLTVGFV YSTEMMAHFS
PQGHPERPAR IDRIWNTLQN DQLTQNMKWL PIRPVRKEEA LLVHSDDHWD KVIAIQYMSD
QQLADSEEYY EQMSLYVMSG TTRAALLSCG GVIESCLAVA RGELKKTFAI VRPPGHHAEP
DEHMGFCFFN NVAVAARVVQ QLTKIKKIMI LDWDVHHGNG TQRAFNEDNS VLYVSIHRYE
QGTYYPCGPF GGMQSCGEGP GLGFSVNVPW PEAGMGDADY LHAFQKVVMP IAMEFAPELV
ISKCHFFCFN VAIAKPPTVY IVSAGFDAAA GDDLGECFVS PAGYAHMTHM LSGLAGGRLV
VALEGGYNLD SISNSALAVA RILMGQAPDE LPPLVASEAA TETVWLVARE QSKYWKSVDP
KSCEPQEGLE DITFSIPEIL KAHRQHYLYT QYDMMQVPLI SAELEQRFSS QIMCTSDIFE
NKTLIVFVHE FGNLRLELAS SATCDVHLER SHLIDFSKKL VTWVKKEGYA LLDANLYPKP
SQAPVTRGNK NPQDIGRDII TYLWDNYIQL SSATRVVFIG HGPGCQPLVE LVDRRALSVI
KSVKAFVQIV GPQIQPTAPQ PSSDEIRAWY KKHSLVILPE NHPFIGPSAK SFNLKRHGTL
VPIQESQQVK MVIQALPGVQ EFVRENLQRY PLSDTTHTNN LARPY
//
