ID   B0E5Y0_ENTDS            Unreviewed;       554 AA.
AC   B0E5Y0;
DT   26-FEB-2008, integrated into UniProtKB/TrEMBL.
DT   26-FEB-2008, sequence version 1.
DT   27-MAR-2024, entry version 55.
DE   RecName: Full=SEC63 domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=EDI_113330 {ECO:0000313|EMBL:EDR30098.1};
OS   Entamoeba dispar (strain ATCC PRA-260 / SAW760).
OC   Eukaryota; Amoebozoa; Evosea; Archamoebae; Mastigamoebida; Entamoebidae;
OC   Entamoeba.
OX   NCBI_TaxID=370354 {ECO:0000313|Proteomes:UP000008076};
RN   [1] {ECO:0000313|Proteomes:UP000008076}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC PRA-260 / SAW760 {ECO:0000313|Proteomes:UP000008076};
RA   Lorenzi H., Inman J., Schobel S., Amedeo P., Caler E.;
RT   "Annotation of Entamoeba dispar SAW760.";
RL   Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; DS547839; EDR30098.1; -; Genomic_DNA.
DR   RefSeq; XP_001733801.1; XM_001733749.1.
DR   AlphaFoldDB; B0E5Y0; -.
DR   EnsemblProtists; EDR30098; EDR30098; EDI_113330.
DR   GeneID; 5878687; -.
DR   KEGG; edi:EDI_113330; -.
DR   VEuPathDB; AmoebaDB:EDI_113330; -.
DR   eggNOG; ENOG502R7R0; Eukaryota.
DR   OMA; ICYNEHQ; -.
DR   OrthoDB; 25215at2759; -.
DR   Proteomes; UP000008076; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.150; C2 domain; 1.
DR   Gene3D; 1.10.3380.10; Sec63 N-terminal domain-like domain; 1.
DR   InterPro; IPR035892; C2_domain_sf.
DR   InterPro; IPR014756; Ig_E-set.
DR   PANTHER; PTHR24075; SEC63 DOMAIN-CONTAINING; 1.
DR   PANTHER; PTHR24075:SF0; TRANSLOCATION PROTEIN SEC63 HOMOLOG; 1.
DR   SUPFAM; SSF81296; E set domains; 1.
DR   SUPFAM; SSF158702; Sec63 N-terminal domain-like; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..35
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        65..82
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        184..206
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   554 AA;  65808 MW;  64E27F4EA32684E4 CRC64;
     MYETYYYDTQ LFIAFITYFV LFLCIVMVCI VGSIFTSRQK IFPCKCKKCQ KLNEMRWKKP
     LTIKRFIAVL IMIVLIFLFY TLNKQRKKCC TEVIEPYNPF KVLNISNSSN RLNIEHRFHD
     IQLRYLIKKV TLEEENVYLR QKYAYELLRN ENRFLEWKSQ WDQLTNSTHL IALPSIFQPN
     TNSMYTIFMV YNTTIFLIIP IVLLICSRKI TINKNNEVHS QYKLVYEKVF DNFVSFSLII
     EAMSSTALVQ RHITYNSYDS KLLPQIRSKV NQDLLNTPHI QTKEVVKAQT LICAYLTRIK
     LPKYLKYTLY SMIPDLRKII IDLINYFFFK GSLDAMVLTT KMGQMIAQAC TVETEYLQLP
     EFQSSQVMYM QKITTSQLGS INALERLQKL HEICYNEHQL ELWKNYLIYF PSNMEIDIGL
     NKEITYTSHS IELEIKIRRK PVMYTLQKSF GPETNQTNQS TELKEKDKTI RSHTPFLRKA
     IKERFYLFVE IENQNLVCYK EKLKIPFSPN IFTINVHVPI PLNINSINFC IYLISDCYLG
     CEYCMKKNVK LLYS
//