ID   B0ERK4_ENTDS            Unreviewed;       282 AA.
AC   B0ERK4;
DT   26-FEB-2008, integrated into UniProtKB/TrEMBL.
DT   26-FEB-2008, sequence version 1.
DT   27-MAR-2024, entry version 50.
DE   SubName: Full=Monoglyceride lipase, putative {ECO:0000313|EMBL:EDR22862.1};
DE            EC=3.1.1.23 {ECO:0000313|EMBL:EDR22862.1};
GN   ORFNames=EDI_038020 {ECO:0000313|EMBL:EDR22862.1};
OS   Entamoeba dispar (strain ATCC PRA-260 / SAW760).
OC   Eukaryota; Amoebozoa; Evosea; Archamoebae; Mastigamoebida; Entamoebidae;
OC   Entamoeba.
OX   NCBI_TaxID=370354 {ECO:0000313|Proteomes:UP000008076};
RN   [1] {ECO:0000313|Proteomes:UP000008076}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC PRA-260 / SAW760 {ECO:0000313|Proteomes:UP000008076};
RA   Lorenzi H., Inman J., Schobel S., Amedeo P., Caler E.;
RT   "Annotation of Entamoeba dispar SAW760.";
RL   Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; DS550522; EDR22862.1; -; Genomic_DNA.
DR   RefSeq; XP_001740730.1; XM_001740678.1.
DR   AlphaFoldDB; B0ERK4; -.
DR   ESTHER; enthi-c4lte6; Monoglyceridelipase_lysophospholip.
DR   EnsemblProtists; EDR22862; EDR22862; EDI_038020.
DR   GeneID; 5885900; -.
DR   KEGG; edi:EDI_038020; -.
DR   VEuPathDB; AmoebaDB:EDI_038020; -.
DR   eggNOG; KOG1455; Eukaryota.
DR   OMA; FVIPENM; -.
DR   OrthoDB; 11534at2759; -.
DR   Proteomes; UP000008076; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0047372; F:acylglycerol lipase activity; IEA:UniProtKB-EC.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR022742; Hydrolase_4.
DR   PANTHER; PTHR11614:SF87; MONOGLYCERIDE LIPASE; 1.
DR   PANTHER; PTHR11614; PHOSPHOLIPASE-RELATED; 1.
DR   Pfam; PF12146; Hydrolase_4; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000313|EMBL:EDR22862.1};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        103..122
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        142..159
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          26..261
FT                   /note="Serine aminopeptidase S33"
FT                   /evidence="ECO:0000259|Pfam:PF12146"
SQ   SEQUENCE   282 AA;  33037 MW;  301F5D4CBB51CBFE CRC64;
     MQINYIETIY SINKFNIYST EWNVEKPQAM IILIHGFCTY AGVMKRMANM LVSHNILLCM
     PDLPYHGRSS GEPKGWVNSF TTFTEICNKY IDQVKEKYNP NGIIPIYIMG HSMGGLIVSI
     IGRQRKDLKG VIGSAPAYEI NNIIVILFYL IIVIILYFIP KLYLPLQYSD KEFPRKEVRQ
     MFEEDQYVTK GKIYLKTIIE MIKYGEREKY SDIFIPFLLI QGINDESVTM KGAQIKSTHL
     KNQYSQFIIY KDCIHCLYEE KNLKEQIINI INWIQKVNKN HN
//