ID B0FNA8_MACMU Unreviewed; 1033 AA.
AC B0FNA8;
DT 26-FEB-2008, integrated into UniProtKB/TrEMBL.
DT 26-FEB-2008, sequence version 1.
DT 24-JAN-2024, entry version 78.
DE SubName: Full=NLR family pyrin domain-containing protein 11 {ECO:0000313|EMBL:ABY67441.1};
GN Name=NLRP11 {ECO:0000313|EMBL:ABY67441.1};
OS Macaca mulatta (Rhesus macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9544 {ECO:0000313|EMBL:ABY67441.1};
RN [1] {ECO:0000313|EMBL:ABY67441.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=18509866; DOI=10.1002/mrd.20937;
RA McDaniel P., Wu X.;
RT "Identification of oocyte-selective NLRP genes in rhesus macaque monkeys
RT (Macaca mulatta).";
RL Mol. Reprod. Dev. 76:151-159(2009).
CC -!- SIMILARITY: Belongs to the NLRP family.
CC {ECO:0000256|ARBA:ARBA00008665}.
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DR EMBL; EU340327; ABY67441.1; -; mRNA.
DR RefSeq; NP_001107581.1; NM_001114109.1.
DR AlphaFoldDB; B0FNA8; -.
DR GeneID; 704053; -.
DR KEGG; mcc:704053; -.
DR CTD; 204801; -.
DR HOGENOM; CLU_002274_2_1_1; -.
DR OrthoDB; 5259946at2759; -.
DR CDD; cd08320; Pyrin_NALPs; 1.
DR Gene3D; 1.10.533.10; Death Domain, Fas; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR004020; DAPIN.
DR InterPro; IPR011029; DEATH-like_dom_sf.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR007111; NACHT_NTPase.
DR InterPro; IPR041267; NLRP_HD2.
DR InterPro; IPR041075; NOD2_WH.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR45690:SF5; NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 11; 1.
DR PANTHER; PTHR45690; NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 12; 1.
DR Pfam; PF05729; NACHT; 1.
DR Pfam; PF17776; NLRC4_HD2; 1.
DR Pfam; PF17779; NOD2_WH; 1.
DR Pfam; PF02758; PYRIN; 1.
DR SMART; SM00368; LRR_RI; 8.
DR SMART; SM01289; PYRIN; 1.
DR SUPFAM; SSF47986; DEATH domain; 1.
DR SUPFAM; SSF52047; RNI-like; 1.
DR PROSITE; PS50824; DAPIN; 1.
DR PROSITE; PS50837; NACHT; 1.
PE 2: Evidence at transcript level;
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614}.
FT DOMAIN 1..91
FT /note="Pyrin"
FT /evidence="ECO:0000259|PROSITE:PS50824"
FT DOMAIN 147..279
FT /note="NACHT"
FT /evidence="ECO:0000259|PROSITE:PS50837"
SQ SEQUENCE 1033 AA; 118125 MW; 6F8AAAED4E9ADBA5 CRC64;
MAESNSTDFD LLWYLENLSD KEFQSFKKYL ARKILDFKLP QVPLINLTKE QLANLLPISY
EGQHIWNMLY SIFLMMRKED LCRKIIGSKR TNQEACKALM RRKITLRWEN HTFGEFHYKF
FCNVASDVFY VLQLAYDSTS CYSANDLNVF LMGDRASGKT MTINLAVMKW INGEMWQNMI
SYVVHLTSHE INQMTDSSLA ELIAKDWPDG QAPIADILSD PKKLLFILED VDNLRFELNV
NEHALCSNST QKVPIPILLV SLLKRQMAPG CWFLISSRPT REENIKMFLK TTDCYVTLQF
SNEKRELYFH SFFNDRQRAS TALMLVHDNE ILTGLCRVAI LCWITCTVLN RQMDKGHDPQ
HCCETPTDLH AHFLADALTS KAGLTTNQYH LGLLRRLCLL AAGGLFLSTL NFSGEDLRCV
GFTEVDFSVL QAVNILLPSS THKDRYKFIH LNVQEFCAAI AFLMAVPNCL IPSGSRGYKE
KREQYCNFNQ VFTFIFGLLN ENRRKILETT FGYQLPMVES FRRYSVEYMK HLGRDQQKLT
HHGSLFYCLF ENQEEEFVKK VVNTLKEVTL YLQSNKDMMV SLYCLEYCCH LRTFKLSVQR
IFEYKEPLVR PTASQMKSLV YWREICSLFC TMDTLWELHL FDSDLNDISE RILSKALEHS
SCKLRTLKLS YISTASGFED LLKALARNRS LIHLSLNCTS ISLNMFSLLR EILDKSTCQI
RHLSLMKCDL RASECGEIAS LLVNGGSLRK LTLTNNPLRN DGVNILCNAL LHPNCTLTSL
ALVFCCLTEQ CCSSLGRVLL LGRTLKQLDL CVNHLQNYGV LHVTFPLIFP TCQLEELYLS
GCFFTNDICQ YIAIVIATNE TLRSLEIGSN SIEDAGMQLL CGGLRHPDCM LVNIGLEECM
LTGACCESLA SVLTTNKTLE RLNILQNQLG DERVVKLLES LILPECVLQI IGLPLNDVSA
ETRRMVMTVK ERKPNLIFLS ETWSVKEGRE IGVIPASQPG SVIPNSNLDY MFFKFPRMST
AMRMSSTASR QPL
//
