ID B0KWA3_CALJA Unreviewed; 261 AA.
AC B0KWA3; F7IJJ4;
DT 18-MAR-2008, integrated into UniProtKB/TrEMBL.
DT 18-MAR-2008, sequence version 1.
DT 27-MAR-2024, entry version 91.
DE RecName: Full=Syntaxin-7 {ECO:0000256|ARBA:ARBA00040006};
GN Name=STX7 {ECO:0000313|EMBL:ABY79126.1};
OS Callithrix jacchus (White-tufted-ear marmoset).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae;
OC Callitrichinae; Callithrix; Callithrix.
OX NCBI_TaxID=9483 {ECO:0000313|EMBL:ABY79126.1};
RN [1] {ECO:0000313|EMBL:ABY79126.1}
RP NUCLEOTIDE SEQUENCE.
RA Antonellis A., Benjamin B., Blakesley R.W., Bouffard G.G., Brinkley C.,
RA Brooks S., Chu G., Chub I., Coleman H., Fuksenko T., Gestole M.,
RA Gregory M., Guan X., Gupta J., Gurson N., Han E., Han J., Hansen N.,
RA Hargrove A., Hines-Harris K., Ho S.-L., Hu P., Hunter G., Hurle B.,
RA Idol J.R., Johnson T., Knight E., Kwong P., Lee-Lin S.-Q., Legaspi R.,
RA Madden M., Maduro Q.L., Maduro V.B., Margulies E.H., Masiello C.,
RA Maskeri B., McDowell J., Merkulov G., Montemayor C., Mullikin J.C.,
RA Park M., Prasad A., Ramsahoye C., Reddix-Dugue N., Riebow N., Schandler K.,
RA Schueler M.G., Sison C., Smith L., Stantripop S., Thomas J.W., Thomas P.J.,
RA Tsipouri V., Young A., Green E.D.;
RT "NISC Comparative Sequencing Initiative.";
RL Submitted (JAN-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:JAB04310.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Bladder {ECO:0000313|EMBL:JAB04310.1}, Cerebellum
RC {ECO:0000313|EMBL:JAB48752.1}, Cerebral cortex
RC {ECO:0000313|EMBL:JAB32317.1}, Hippocampus
RC {ECO:0000313|EMBL:JAB17893.1}, and Skeletal muscle
RC {ECO:0000313|EMBL:JAB38326.1};
RX PubMed=25243066; DOI=10.1186/2047-217X-3-14;
RA Maudhoo M.D., Ren D., Gradnigo J.S., Gibbs R.M., Lubker A.C.,
RA Moriyama E.N., French J.A., Norgren R.B.Jr.;
RT "De novo assembly of the common marmoset transcriptome from NextGen mRNA
RT sequences.";
RL Gigascience 3:14-14(2014).
CC -!- FUNCTION: May be involved in protein trafficking from the plasma
CC membrane to the early endosome (EE) as well as in homotypic fusion of
CC endocytic organelles. Mediates the endocytic trafficking from early
CC endosomes to late endosomes and lysosomes.
CC {ECO:0000256|ARBA:ARBA00037599}.
CC -!- SUBCELLULAR LOCATION: Early endosome membrane
CC {ECO:0000256|ARBA:ARBA00037832}; Single-pass type IV membrane protein
CC {ECO:0000256|ARBA:ARBA00037832}. Endosome membrane
CC {ECO:0000256|ARBA:ARBA00037867}; Single-pass type IV membrane protein
CC {ECO:0000256|ARBA:ARBA00037867}. Membrane
CC {ECO:0000256|ARBA:ARBA00004211}; Single-pass type IV membrane protein
CC {ECO:0000256|ARBA:ARBA00004211}.
CC -!- SIMILARITY: Belongs to the syntaxin family.
CC {ECO:0000256|ARBA:ARBA00009063, ECO:0000256|RuleBase:RU003858}.
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DR EMBL; DP000570; ABY79126.1; -; Genomic_DNA.
DR EMBL; GAMT01007551; JAB04310.1; -; mRNA.
DR EMBL; GAMT01007550; JAB04311.1; -; mRNA.
DR EMBL; GAMS01005243; JAB17893.1; -; mRNA.
DR EMBL; GAMS01005242; JAB17894.1; -; mRNA.
DR EMBL; GAMR01001615; JAB32317.1; -; mRNA.
DR EMBL; GAMQ01003525; JAB38326.1; -; mRNA.
DR EMBL; GAMP01004003; JAB48752.1; -; mRNA.
DR RefSeq; XP_002747014.1; XM_002746968.4.
DR RefSeq; XP_017826889.1; XM_017971400.1.
DR RefSeq; XP_017826890.1; XM_017971401.1.
DR AlphaFoldDB; B0KWA3; -.
DR STRING; 9483.ENSCJAP00000005344; -.
DR GeneID; 100413538; -.
DR KEGG; cjc:100413538; -.
DR CTD; 8417; -.
DR eggNOG; KOG0811; Eukaryota.
DR HOGENOM; CLU_059257_1_1_1; -.
DR InParanoid; B0KWA3; -.
DR OrthoDB; 200189at2759; -.
DR TreeFam; TF315607; -.
DR Bgee; ENSCJAG00000002932; Expressed in kidney and 6 other cell types or tissues.
DR GO; GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005484; F:SNAP receptor activity; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR CDD; cd15875; SNARE_syntaxin7; 1.
DR CDD; cd00179; SynN; 1.
DR Gene3D; 1.20.5.110; -; 1.
DR Gene3D; 1.20.58.70; -; 1.
DR InterPro; IPR010989; SNARE.
DR InterPro; IPR045242; Syntaxin.
DR InterPro; IPR006012; Syntaxin/epimorphin_CS.
DR InterPro; IPR006011; Syntaxin_N.
DR InterPro; IPR000727; T_SNARE_dom.
DR PANTHER; PTHR19957; SYNTAXIN; 1.
DR PANTHER; PTHR19957:SF90; SYNTAXIN-7; 1.
DR Pfam; PF05739; SNARE; 1.
DR Pfam; PF14523; Syntaxin_2; 1.
DR SMART; SM00503; SynN; 1.
DR SMART; SM00397; t_SNARE; 1.
DR SUPFAM; SSF47661; t-snare proteins; 1.
DR PROSITE; PS00914; SYNTAXIN; 1.
DR PROSITE; PS50192; T_SNARE; 1.
PE 2: Evidence at transcript level;
KW Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Endosome {ECO:0000256|ARBA:ARBA00022753};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 238..259
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 165..227
FT /note="T-SNARE coiled-coil homology"
FT /evidence="ECO:0000259|PROSITE:PS50192"
FT REGION 128..148
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 261 AA; 29789 MW; C0AC1BBB1FF3ACD4 CRC64;
MSYTPGVGGD PAQLAQRISS NIQKITQCSV EIQRTLNQLG TPQDSPELRQ QLQQKQQYTN
QLAKETDKYI KEFGSLPTTP SEQRQRKIQK DRLVAEFTTS LTNFQKVQRQ AAEREKEFVA
RVRASSRVSG GFPEDSSKER NLVSWESQTQ PQVQVQDEEI TEDDLRLIHE RESSIRQLEA
DIMDINEIFK DLGMMIHEQG DVIDSIEANV ENAEVHVQQA NQQLSRAADY QRKSRKTLCI
IILILVIGVA IIGFIIWGLN H
//
