ID B0P9W2_9FIRM Unreviewed; 1027 AA.
AC B0P9W2;
DT 08-APR-2008, integrated into UniProtKB/TrEMBL.
DT 08-APR-2008, sequence version 1.
DT 24-JAN-2024, entry version 49.
DE SubName: Full=Heavy metal efflux pump, CzcA family {ECO:0000313|EMBL:EDS11640.1};
GN Name=czcA {ECO:0000313|EMBL:EDS11640.1};
GN ORFNames=ANACOL_01531 {ECO:0000313|EMBL:EDS11640.1};
OS Anaerotruncus colihominis DSM 17241.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC Anaerotruncus.
OX NCBI_TaxID=445972 {ECO:0000313|EMBL:EDS11640.1, ECO:0000313|Proteomes:UP000003803};
RN [1] {ECO:0000313|EMBL:EDS11640.1, ECO:0000313|Proteomes:UP000003803}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17241 {ECO:0000313|EMBL:EDS11640.1,
RC ECO:0000313|Proteomes:UP000003803};
RA Sudarsanam P., Ley R., Guruge J., Turnbaugh P.J., Mahowald M., Liep D.,
RA Gordon J.;
RT "Draft genome sequence of Anaerotruncus colihominis(DSM 17241).";
RL Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EDS11640.1, ECO:0000313|Proteomes:UP000003803}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17241 {ECO:0000313|EMBL:EDS11640.1,
RC ECO:0000313|Proteomes:UP000003803};
RA Fulton L., Clifton S., Fulton B., Xu J., Minx P., Pepin K.H., Johnson M.,
RA Thiruvilangam P., Bhonagiri V., Nash W.E., Mardis E.R., Wilson R.K.;
RL Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EDS11640.1}.
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DR EMBL; ABGD02000012; EDS11640.1; -; Genomic_DNA.
DR RefSeq; WP_006874827.1; NZ_DS544181.1.
DR AlphaFoldDB; B0P9W2; -.
DR STRING; 169435.ERS852551_01063; -.
DR GeneID; 72465067; -.
DR eggNOG; COG0841; Bacteria.
DR HOGENOM; CLU_002755_1_2_9; -.
DR Proteomes; UP000003803; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 3.30.70.1430; Multidrug efflux transporter AcrB pore domain; 2.
DR Gene3D; 3.30.70.1440; Multidrug efflux transporter AcrB pore domain; 1.
DR Gene3D; 3.30.70.1320; Multidrug efflux transporter AcrB pore domain like; 1.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR027463; AcrB_DN_DC_subdom.
DR InterPro; IPR001036; Acrflvin-R.
DR PANTHER; PTHR32063; -; 1.
DR PANTHER; PTHR32063:SF0; SWARMING MOTILITY PROTEIN SWRC; 1.
DR Pfam; PF00873; ACR_tran; 1.
DR PRINTS; PR00702; ACRIFLAVINRP.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 330..349
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 356..376
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 382..403
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 424..447
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 459..483
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 518..538
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 839..859
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 866..890
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 896..915
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 942..960
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 972..996
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1004..1027
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1027 AA; 111370 MW; A40AD0C52B0F4DAF CRC64;
MNLTKLVLKR PVSMVMIILA LIVFGFSAIT GAPLELMPEM EMPVLLVMTT YPGAGPQEVE
DLVTSQLESS VSTLNGIKTI QSVSQDSVSL MVLQLEYGTN MDVAHMDLQE KLNMYSGALP
DDAQDPIIIE MDLNSMSAIT LSARATGDID LLSYIDEEIK PEFEKLGGVA SVDVSGGQEN
YISVELDEQR LKQYGLDMST IVSFIGAADF SIPVGDIDRG DQSLSLRGGV SYDTVESLGN
IPITLRSGQV IHLSDVAHIY DATADADSIS RYNGNETVSL GIKKRQSAGT IEVTEAVVKT
MEQINARNMG VELSVINDTS DSIRSSVNSV IKTLISAIIL CMIVLFIFFG DWKASLIVGS
SIPVSVLTTL ILMNAFGFSF NIVSLGGLVI GVGMMVDNSI VVLESCFQRR ERNLTFRDAA
IEGARIVTSS VAASTLTTVV VFLPISIMEG LSGQMFRQLG FTIVFSLTAS LISALTIVPL
LFYRLAPKEK EDSHVNRVLN KITIAYGNFL KKTFRHKLLV VLISVGLLVG SFMLLPFIHF
QLMPDIDQGT ISISVETKPG LKLEKVDALM TQLESMVQES TDVERYYLTA GGGAMTSTGN
ESGSLTVYLK ADRERSTNEW IDEWREQTKD IPNCDISISA QSMMSFSSGG SVDVNLQGND
LDLLREASKD VEAVMGQNPN IVRVSSTLTS GNPQAEIVVD PIKATAVGMT PQQVVGTVYN
MVSGTSPATM DRDGREYDIR IEFPKERFQT VSDLSGLILT SPSGKQVPLL DIASIEYSNA
PQSIQRKNNQ YIVTISGQPT TASALTAGEE IKQAVAELEL PEGVAVTQNQ ADEQMMEEFG
ALFGAIATAV FLVFMVMAMQ FESCRFSIIV MICIPFSLIG SFGLMLLSGV TMSMPSLIGF
LMLVGTVINN GILFIDTANQ YRSSMDAETA LVYAGRSRLR PILMTTLTTV LSMIPMGLGI
GEGSEAMQGM AVVIIGGLTA STILTLLLLP TFYLLFRGRP HKEYKKEEDT KNGNTHPDLS
QEELITQ
//
