ID B0S4S0_SALSA Unreviewed; 298 AA.
AC B0S4S0;
DT 08-APR-2008, integrated into UniProtKB/TrEMBL.
DT 08-APR-2008, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE RecName: Full=FXYD domain-containing ion transport regulator {ECO:0000256|RuleBase:RU364131};
GN Name=fxyd5b {ECO:0000313|RefSeq:NP_001117196.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|EMBL:DAA06142.1};
RN [1] {ECO:0000313|EMBL:DAA06142.1, ECO:0000313|RefSeq:NP_001117196.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=18256141; DOI=10.1152/ajpregu.00454.2007;
RA Tipsmark C.K.;
RT "Identification of FXYD protein genes in a teleost: tissue-specific
RT expression and response to salinity change.";
RL Am. J. Physiol. Regul. Integr. Comp. Physiol. 294:R1367-R1378(2008).
RN [2] {ECO:0000313|RefSeq:NP_001117196.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the FXYD family. {ECO:0000256|ARBA:ARBA00005948,
CC ECO:0000256|RuleBase:RU364131}.
CC -!- SIMILARITY: Belongs to the immunoglobulin superfamily. ICAM family.
CC {ECO:0000256|ARBA:ARBA00005925}.
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DR EMBL; BK006254; DAA06142.1; -; mRNA.
DR RefSeq; NP_001117196.1; NM_001123724.1.
DR STRING; 8030.ENSSSAP00000061995; -.
DR PaxDb; 8030-ENSSSAP00000061995; -.
DR GeneID; 100141318; -.
DR KEGG; sasa:100141318; -.
DR CTD; 100141318; -.
DR OMA; QPVICHT; -.
DR OrthoDB; 3971453at2759; -.
DR Proteomes; UP000087266; Chromosome ssa05.
DR Bgee; ENSSSAG00000056570; Expressed in semen and 13 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005178; F:integrin binding; IEA:InterPro.
DR GO; GO:0099106; F:ion channel regulator activity; IEA:InterPro.
DR GO; GO:0098609; P:cell-cell adhesion; IEA:InterPro.
DR GO; GO:0006811; P:monoatomic ion transport; IEA:UniProtKB-KW.
DR GO; GO:0043269; P:regulation of monoatomic ion transport; IEA:InterPro.
DR CDD; cd20323; FXYD_FXYD5; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR Gene3D; 1.20.5.780; Single helix bin; 1.
DR InterPro; IPR013768; ICAM_N.
DR InterPro; IPR047012; ICAM_VCAM.
DR InterPro; IPR003987; ICAM_VCAM_N.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003597; Ig_C1-set.
DR InterPro; IPR000272; Ion-transport_regulator_FXYD.
DR PANTHER; PTHR13771; INTERCELLULAR ADHESION MOLECULE; 1.
DR PANTHER; PTHR13771:SF9; INTERCELLULAR ADHESION MOLECULE 5; 1.
DR Pfam; PF02038; ATP1G1_PLM_MAT8; 1.
DR Pfam; PF07654; C1-set; 1.
DR Pfam; PF03921; ICAM_N; 1.
DR PRINTS; PR01472; ICAMVCAM1.
DR SUPFAM; SSF48726; Immunoglobulin; 2.
DR PROSITE; PS50835; IG_LIKE; 1.
PE 2: Evidence at transcript level;
KW Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW Ion transport {ECO:0000256|RuleBase:RU364131};
KW Membrane {ECO:0000256|RuleBase:RU364131};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW Signal {ECO:0000256|RuleBase:RU364131, ECO:0000313|RefSeq:NP_001117196.1};
KW Transmembrane {ECO:0000256|RuleBase:RU364131};
KW Transmembrane helix {ECO:0000256|RuleBase:RU364131};
KW Transport {ECO:0000256|RuleBase:RU364131}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|RuleBase:RU364131"
FT CHAIN 26..298
FT /note="FXYD domain-containing ion transport regulator"
FT /evidence="ECO:0000256|RuleBase:RU364131,
FT ECO:0000313|RefSeq:NP_001117196.1"
FT /id="PRO_5009732055"
FT TRANSMEM 253..274
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364131"
FT DOMAIN 113..210
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
SQ SEQUENCE 298 AA; 33238 MW; 0122E2B075968BD8 CRC64;
MDTKIQLSWT AVCLFLTLPG APTHASCPVE LKPPRVVVRY GDSVSVNCTS STDPEGMGWE
ATSGGTELHE NVNLVTWTVE SLIDWTIEPK CYINPQNGSQ CTETLPVILY KTPDSVSISP
LSHSGPMMEG KEYQLQCDIQ NIAPLQNLVV RWYKGNETIE TQRFNDSTKE SVNMSSTITI
THRRYEGEVE YRCEAELDLG PEEPKPSALS KPLKVTVYLT PSPTTSENTI KRTIAPLVAW
DAKWDEAFNY DYYFLRVVGL SMAAVLFILG IMVISCGKIC RMPRCHVGTG KSYQVARE
//
