ID   B0SM21_LEPBP            Unreviewed;       257 AA.
AC   B0SM21;
DT   08-APR-2008, integrated into UniProtKB/TrEMBL.
DT   08-APR-2008, sequence version 1.
DT   27-MAR-2024, entry version 58.
DE   RecName: Full=RND efflux pump membrane fusion protein barrel-sandwich domain-containing protein {ECO:0000259|Pfam:PF16576};
GN   OrderedLocusNames=LEPBI_I2570 {ECO:0000313|EMBL:ABZ98651.1};
OS   Leptospira biflexa serovar Patoc (strain Patoc 1 / ATCC 23582 / Paris).
OC   Bacteria; Spirochaetota; Spirochaetia; Leptospirales; Leptospiraceae;
OC   Leptospira.
OX   NCBI_TaxID=456481 {ECO:0000313|EMBL:ABZ98651.1, ECO:0000313|Proteomes:UP000001847};
RN   [1] {ECO:0000313|EMBL:ABZ98651.1, ECO:0000313|Proteomes:UP000001847}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Patoc 1 / ATCC 23582 / Paris
RC   {ECO:0000313|Proteomes:UP000001847};
RX   PubMed=18270594; DOI=10.1371/journal.pone.0001607;
RA   Picardeau M., Bulach D.M., Bouchier C., Zuerner R.L., Zidane N.,
RA   Wilson P.J., Creno S., Kuczek E.S., Bommezzadri S., Davis J.C., McGrath A.,
RA   Johnson M.J., Boursaux-Eude C., Seemann T., Rouy Z., Coppel R.L.,
RA   Rood J.I., Lajus A., Davies J.K., Medigue C., Adler B.;
RT   "Genome sequence of the saprophyte Leptospira biflexa provides insights
RT   into the evolution of Leptospira and the pathogenesis of leptospirosis.";
RL   PLoS ONE 3:E1607-E1607(2008).
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DR   EMBL; CP000786; ABZ98651.1; -; Genomic_DNA.
DR   AlphaFoldDB; B0SM21; -.
DR   STRING; 456481.LEPBI_I2570; -.
DR   KEGG; lbi:LEPBI_I2570; -.
DR   HOGENOM; CLU_089610_0_0_12; -.
DR   Proteomes; UP000001847; Chromosome I.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 2.40.30.170; -; 1.
DR   Gene3D; 2.40.50.100; -; 1.
DR   InterPro; IPR032317; HlyD_D23.
DR   InterPro; IPR011053; Single_hybrid_motif.
DR   PANTHER; PTHR32347; EFFLUX SYSTEM COMPONENT YKNX-RELATED; 1.
DR   PANTHER; PTHR32347:SF14; EFFLUX SYSTEM COMPONENT YKNX-RELATED; 1.
DR   Pfam; PF16576; HlyD_D23; 1.
DR   SUPFAM; SSF51230; Single hybrid motif; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001847};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        7..26
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          90..169
FT                   /note="RND efflux pump membrane fusion protein barrel-
FT                   sandwich"
FT                   /evidence="ECO:0000259|Pfam:PF16576"
SQ   SEQUENCE   257 AA;  28447 MW;  BB8633CB636E8F2B CRC64;
     MMNRKKIFAM IATFVIILSL VFLFFLRNSK SDRLSIQKGS LVEAVYALGT VKPVDSFVLK
     FGIAASIRDI FVEEGQSVKK GDPLLVNDSG ITFRSPFAGT ITKLNVAKNE TAMPGIPILE
     IQNLKEVYVS VSLDQESALR VKPAQHAQLS FESIRGNVYK GEVERIYPSN GQFLVRIAPH
     ELPQGILPDM TTDVAIEVSS KDNVILVPLV AVERGKVVRY RNGKREKMEI RIGAINSEFG
     ELIQGDLLEG DEVLVKN
//