ID B0VUG9_ACIBS Unreviewed; 347 AA.
AC B0VUG9;
DT 08-APR-2008, integrated into UniProtKB/TrEMBL.
DT 08-APR-2008, sequence version 1.
DT 27-MAR-2024, entry version 80.
DE SubName: Full=5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferase {ECO:0000313|EMBL:CAP02031.1};
DE EC=2.1.1.14 {ECO:0000313|EMBL:CAP02031.1};
GN Name=metE {ECO:0000313|EMBL:CAP02031.1};
GN OrderedLocusNames=ABSDF2728 {ECO:0000313|EMBL:CAP02031.1};
OS Acinetobacter baumannii (strain SDF).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Moraxellales; Moraxellaceae;
OC Acinetobacter; Acinetobacter calcoaceticus/baumannii complex.
OX NCBI_TaxID=509170 {ECO:0000313|EMBL:CAP02031.1, ECO:0000313|Proteomes:UP000001741};
RN [1] {ECO:0000313|EMBL:CAP02031.1, ECO:0000313|Proteomes:UP000001741}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SDF {ECO:0000313|EMBL:CAP02031.1,
RC ECO:0000313|Proteomes:UP000001741};
RX PubMed=18350144; DOI=10.1371/journal.pone.0001805;
RA Vallenet D., Nordmann P., Barbe V., Poirel L., Mangenot S., Bataille E.,
RA Dossat C., Gas S., Kreimeyer A., Lenoble P., Oztas S., Poulain J.,
RA Segurens B., Robert C., Abergel C., Claverie J.-M., Raoult D., Medigue C.,
RA Weissenbach J., Cruveiller S.;
RT "Comparative analysis of Acinetobacters: three genomes for three
RT lifestyles.";
RL PLoS ONE 3:E1805-E1805(2008).
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SIMILARITY: Belongs to the vitamin-B12 independent methionine synthase
CC family. {ECO:0000256|ARBA:ARBA00009553}.
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DR EMBL; CU468230; CAP02031.1; -; Genomic_DNA.
DR AlphaFoldDB; B0VUG9; -.
DR KEGG; abm:ABSDF2728; -.
DR HOGENOM; CLU_040013_3_0_6; -.
DR Proteomes; UP000001741; Chromosome.
DR GO; GO:0003871; F:5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0009086; P:methionine biosynthetic process; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd03311; CIMS_C_terminal_like; 1.
DR Gene3D; 3.20.20.210; -; 1.
DR InterPro; IPR002629; Met_Synth_C/arc.
DR InterPro; IPR016456; Met_Synthase_cat.
DR InterPro; IPR038071; UROD/MetE-like_sf.
DR PANTHER; PTHR30519; 5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE; 1.
DR PANTHER; PTHR30519:SF0; 5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE; 1.
DR Pfam; PF01717; Meth_synt_2; 1.
DR PIRSF; PIRSF005632; Met_synth_catalytic_prd; 1.
DR SUPFAM; SSF51726; UROD/MetE-like; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Methyltransferase {ECO:0000313|EMBL:CAP02031.1};
KW Transferase {ECO:0000313|EMBL:CAP02031.1};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 5..329
FT /note="Cobalamin-independent methionine synthase MetE C-
FT terminal/archaeal"
FT /evidence="ECO:0000259|Pfam:PF01717"
SQ SEQUENCE 347 AA; 39128 MW; 268B385BA258A46D CRC64;
MKKLLPTSTA GSLPKPSWLA EPEKLWSPWK LENEGLIEGK KDALRLALHE QKLAGIDIVS
DGEQTRQHFV TTFIEHLNGV DFEKRETVRI RDRYDASVPS VVGAVSRQKP VFVEDAKFLR
QQTDQPIKWA LPGPMTMIDT LYDGHYKSRE KLAWEFAKIL NQEAKELEAA GVDIIQFDEP
AFNVFFDEVN DWGIATLERA IEGLKCETAV HICYGYGIKA NTDWKKTLGS EWRQYEEAFP
KLQTSNIDII SLECHNSRVP IDLLELIRGK KVMVGAIDVA TNHIETPEEV ANTLRKALQF
VDSDKLYPCT NCGMAPLSRE VARGKLNALS AGAEIVRREL TGYDLTA
//
