ID B0WHS4_CULQU Unreviewed; 837 AA.
AC B0WHS4;
DT 08-APR-2008, integrated into UniProtKB/TrEMBL.
DT 08-APR-2008, sequence version 1.
DT 24-JAN-2024, entry version 85.
DE RecName: Full=Armadillo segment polarity protein {ECO:0000256|ARBA:ARBA00022289};
GN Name=6038461 {ECO:0000313|EnsemblMetazoa:CPIJ006700-PA};
GN ORFNames=CpipJ_CPIJ006700 {ECO:0000313|EMBL:EDS27941.1};
OS Culex quinquefasciatus (Southern house mosquito) (Culex pungens).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Culicini; Culex; Culex.
OX NCBI_TaxID=7176;
RN [1] {ECO:0000313|EMBL:EDS27941.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JHB {ECO:0000313|EMBL:EDS27941.1};
RG The Broad Institute Genome Sequencing Platform;
RA Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.,
RA Hannick L., Megy K., O'Leary S., Pearson M., Haas B.J., Mauceli E.,
RA Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L., Amedeo P.,
RA Antoine C.H., Arensburger P., Bidwell S.L., Crawford M., Camaro F.,
RA Devon K., Engels R., Hammond M., Howarth C., Koehrsen M., Lawson D.,
RA Montgomery P., Nene V., Nusbaum C., Puiu D., Romero-Severson J.,
RA Severson D.W., Shumway M., Sisk P., Stolte C., Zeng Q., Eisenstadt E.,
RA Fraser-Liggett C., Strausberg R., Galagan J., Birren B., Collins F.H.;
RT "Annotation of Culex pipiens quinquefasciatus.";
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:CPIJ006700-PA}
RP IDENTIFICATION.
RC STRAIN=JHB {ECO:0000313|EnsemblMetazoa:CPIJ006700-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004413};
CC Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004413};
CC Cytoplasmic side {ECO:0000256|ARBA:ARBA00004413}. Membrane
CC {ECO:0000256|ARBA:ARBA00004287}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004287}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004287}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; DS231939; EDS27941.1; -; Genomic_DNA.
DR RefSeq; XP_001848258.1; XM_001848206.1.
DR AlphaFoldDB; B0WHS4; -.
DR STRING; 7176.B0WHS4; -.
DR EnsemblMetazoa; CPIJ006700-RA; CPIJ006700-PA; CPIJ006700.
DR KEGG; cqu:CpipJ_CPIJ006700; -.
DR VEuPathDB; VectorBase:CPIJ006700; -.
DR VEuPathDB; VectorBase:CQUJHB005805; -.
DR eggNOG; KOG4203; Eukaryota.
DR HOGENOM; CLU_008757_1_1_1; -.
DR InParanoid; B0WHS4; -.
DR OMA; DPLMFDM; -.
DR OrthoDB; 50711at2759; -.
DR Proteomes; UP000002320; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0045296; F:cadherin binding; IEA:InterPro.
DR GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
DR CDD; cd21726; CTNNAbd_dArm; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR000225; Armadillo.
DR InterPro; IPR013284; Beta-catenin.
DR PANTHER; PTHR45976; ARMADILLO SEGMENT POLARITY PROTEIN; 1.
DR PANTHER; PTHR45976:SF1; ARMADILLO SEGMENT POLARITY PROTEIN; 1.
DR Pfam; PF00514; Arm; 4.
DR PRINTS; PR01869; BCATNINFAMLY.
DR SMART; SM00185; ARM; 11.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS50176; ARM_REPEAT; 9.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002320};
KW Wnt signaling pathway {ECO:0000256|ARBA:ARBA00022687}.
FT REPEAT 161..201
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 203..246
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 245..287
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 287..329
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 329..372
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 410..452
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 452..489
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 499..542
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 609..652
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REGION 726..837
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 821..837
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 837 AA; 90735 MW; D5529F57F4918811 CRC64;
MAPGDNDNCI MPHMSHNPYN PSPDMPMPSA KEQTLMWQQN SYIGDSGIHS GAVTQVPSLS
GKGDDDMEDD PLMFDMDQGF SQNFTQDQVD DMNQQLSTTR SQRVRAAMFP ETLEEGIEIP
STQFDPQQPT AVQRLSEPSQ MLKHAVVNLI NYQDDADLAT RAIPELIKLL NDEDQVVVSQ
AAMMVHQLSK KEASRHAIMN SPQMVAALVR ALSQSNDLET TKGAVGTLHN LSHHRQGLLA
IFKSGGIPAL VKLLSSPVES VLFYAITTLH NLLLHQDGSK MAVRLAGGLQ KMVALLQRNN
VKFLAIVTDC LQILAYGNQE SKLIILASTG PSELVRIMRS YDYEKLLWTT SRVLKVLSVC
SSNKPAIVEA GGMQALAMHL GNPSQRLVQN CLWTLRNLSD AATKVDGLET LLSGLVTVLG
SSDVNVVTCA AGILSNLTCN NQRNKVTVCQ VGGVEALVGT IINAGDREEI TEPAVCALRH
LTSRHPESEQ AQNIVRNGYG LPVIVKLLNP PSRWPLIKAV IGLIRNLALC PSNAAPLREN
GAIHLLVRLL FKAFQDTQRQ RSSVATNGSQ PPGAYADGVR MEEIVEGTVG ALHILSKEEL
NRQLIRQQNV IPIFVQLLFY NDIENIQRVA AGVLCELAVD KEVAEMIEAE GATAPLTELL
NSANEGVATY AAAVLFKMSE DKSMDYKKRF SSELTTLPVF RDDSMWNNGE LGMGPDLQDI
LSPDQAYEGL YGQGPPSVHS SHGGRAFQQG YDTLPIDSMQ GLEIGGGGSG GQNGGPQQQN
GGGPVGPPPS GQPTSPYAMD MDVGEMDASE LTFDHLDVMP SPPQDNNQVA AWYDTDL
//
