ID B0WLP5_CULQU Unreviewed; 169 AA.
AC B0WLP5;
DT 08-APR-2008, integrated into UniProtKB/TrEMBL.
DT 08-APR-2008, sequence version 1.
DT 27-MAR-2024, entry version 73.
DE SubName: Full=Caspase-1 {ECO:0000313|EMBL:EDS30610.1, ECO:0000313|EnsemblMetazoa:CPIJ008253-PA};
GN Name=6040178 {ECO:0000313|EnsemblMetazoa:CPIJ008253-PA};
GN ORFNames=CpipJ_CPIJ008253 {ECO:0000313|EMBL:EDS30610.1};
OS Culex quinquefasciatus (Southern house mosquito) (Culex pungens).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Culicini; Culex; Culex.
OX NCBI_TaxID=7176;
RN [1] {ECO:0000313|EMBL:EDS30610.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JHB {ECO:0000313|EMBL:EDS30610.1};
RG The Broad Institute Genome Sequencing Platform;
RA Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.,
RA Hannick L., Megy K., O'Leary S., Pearson M., Haas B.J., Mauceli E.,
RA Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L., Amedeo P.,
RA Antoine C.H., Arensburger P., Bidwell S.L., Crawford M., Camaro F.,
RA Devon K., Engels R., Hammond M., Howarth C., Koehrsen M., Lawson D.,
RA Montgomery P., Nene V., Nusbaum C., Puiu D., Romero-Severson J.,
RA Severson D.W., Shumway M., Sisk P., Stolte C., Zeng Q., Eisenstadt E.,
RA Fraser-Liggett C., Strausberg R., Galagan J., Birren B., Collins F.H.;
RT "Annotation of Culex pipiens quinquefasciatus.";
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:CPIJ008253-PA}
RP IDENTIFICATION.
RC STRAIN=JHB {ECO:0000313|EnsemblMetazoa:CPIJ008253-PA};
RG EnsemblMetazoa;
RL Submitted (FEB-2021) to UniProtKB.
CC -!- SIMILARITY: Belongs to the peptidase C14A family.
CC {ECO:0000256|ARBA:ARBA00010134}.
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DR EMBL; DS231989; EDS30610.1; -; Genomic_DNA.
DR RefSeq; XP_001849629.1; XM_001849577.1.
DR AlphaFoldDB; B0WLP5; -.
DR STRING; 7176.B0WLP5; -.
DR MEROPS; C14.016; -.
DR EnsemblMetazoa; CPIJ008253-RA; CPIJ008253-PA; CPIJ008253.
DR KEGG; cqu:CpipJ_CPIJ008253; -.
DR VEuPathDB; VectorBase:CPIJ008253; -.
DR VEuPathDB; VectorBase:CQUJHB017973; -.
DR eggNOG; KOG3573; Eukaryota.
DR HOGENOM; CLU_036904_3_3_1; -.
DR InParanoid; B0WLP5; -.
DR OMA; FIIQVKH; -.
DR OrthoDB; 2873736at2759; -.
DR Proteomes; UP000002320; Unassembled WGS sequence.
DR GO; GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR Gene3D; 3.40.50.1460; -; 1.
DR InterPro; IPR029030; Caspase-like_dom_sf.
DR InterPro; IPR011600; Pept_C14_caspase.
DR InterPro; IPR001309; Pept_C14_p20.
DR InterPro; IPR015917; Pept_C14A.
DR PANTHER; PTHR47901; CASPASE RECRUITMENT DOMAIN-CONTAINING PROTEIN 18; 1.
DR PANTHER; PTHR47901:SF8; CASPASE-3; 1.
DR Pfam; PF00656; Peptidase_C14; 1.
DR PRINTS; PR00376; IL1BCENZYME.
DR SMART; SM00115; CASc; 1.
DR SUPFAM; SSF52129; Caspase-like; 1.
DR PROSITE; PS50208; CASPASE_P20; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000002320}.
FT DOMAIN 46..169
FT /note="Caspase family p20"
FT /evidence="ECO:0000259|PROSITE:PS50208"
SQ SEQUENCE 169 AA; 19278 MW; 69B58E220197618E CRC64;
MDKGSTNEVD VLGLMEYIPN SSMPSANITP KSRPTVEENY NTNHKYRGLA LIFCNMEFQK
ELKMPKRVAT EKDRDDICDA LENLSFNVKV NNDLNKEEVQ KTLKEWSQEK HHIDNDCLVV
VIMTYGGNGF VYAKDGKYEV DTLWKNFVGN ACPSLIGKPK IFFIQGLYG
//
