ID   B0WP50_CULQU            Unreviewed;      1059 AA.
AC   B0WP50;
DT   08-APR-2008, integrated into UniProtKB/TrEMBL.
DT   08-APR-2008, sequence version 1.
DT   27-MAR-2024, entry version 75.
DE   RecName: Full=WH2 domain-containing protein {ECO:0000259|PROSITE:PS51082};
GN   Name=6041190 {ECO:0000313|EnsemblMetazoa:CPIJ008872-PA};
GN   ORFNames=CpipJ_CPIJ008872 {ECO:0000313|EMBL:EDS32095.1};
OS   Culex quinquefasciatus (Southern house mosquito) (Culex pungens).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Culicinae; Culicini; Culex; Culex.
OX   NCBI_TaxID=7176;
RN   [1] {ECO:0000313|EMBL:EDS32095.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JHB {ECO:0000313|EMBL:EDS32095.1};
RG   The Broad Institute Genome Sequencing Platform;
RA   Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.,
RA   Hannick L., Megy K., O'Leary S., Pearson M., Haas B.J., Mauceli E.,
RA   Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L., Amedeo P.,
RA   Antoine C.H., Arensburger P., Bidwell S.L., Crawford M., Camaro F.,
RA   Devon K., Engels R., Hammond M., Howarth C., Koehrsen M., Lawson D.,
RA   Montgomery P., Nene V., Nusbaum C., Puiu D., Romero-Severson J.,
RA   Severson D.W., Shumway M., Sisk P., Stolte C., Zeng Q., Eisenstadt E.,
RA   Fraser-Liggett C., Strausberg R., Galagan J., Birren B., Collins F.H.;
RT   "Annotation of Culex pipiens quinquefasciatus.";
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:CPIJ008872-PA}
RP   IDENTIFICATION.
RC   STRAIN=JHB {ECO:0000313|EnsemblMetazoa:CPIJ008872-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; DS232020; EDS32095.1; -; Genomic_DNA.
DR   RefSeq; XP_001850484.1; XM_001850432.1.
DR   AlphaFoldDB; B0WP50; -.
DR   STRING; 7176.B0WP50; -.
DR   EnsemblMetazoa; CPIJ008872-RA; CPIJ008872-PA; CPIJ008872.
DR   KEGG; cqu:CpipJ_CPIJ008872; -.
DR   VEuPathDB; VectorBase:CPIJ008872; -.
DR   VEuPathDB; VectorBase:CQUJHB007480; -.
DR   eggNOG; KOG3751; Eukaryota.
DR   HOGENOM; CLU_002721_0_0_1; -.
DR   InParanoid; B0WP50; -.
DR   OMA; NSAHQPA; -.
DR   Proteomes; UP000002320; Unassembled WGS sequence.
DR   GO; GO:0003779; F:actin binding; IEA:InterPro.
DR   InterPro; IPR003124; WH2_dom.
DR   PROSITE; PS51082; WH2; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000002320}.
FT   DOMAIN          1036..1055
FT                   /note="WH2"
FT                   /evidence="ECO:0000259|PROSITE:PS51082"
FT   REGION          1..128
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          237..259
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          340..365
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          430..449
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          466..509
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          793..818
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        8..50
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        60..74
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        239..258
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        495..509
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1059 AA;  116286 MW;  25687C620CB308DF CRC64;
     MEDSKQKLQT VSKLNAVNSA HQPATPTTTP ANVSKVMLNV DQSSGPSSLS PEVDRKPPPT
     NGASSVSIMI VKEEQPTTNG HHEPSKPATP IQVSKVHIVP SEQDVSVDES EESIERRLSN
     GNSSDEDIKI YNIESGKELR IPEKKDQTVR SPSPEEEEQW TYTLPAPPKF ADSSIKSGEY
     DEKQRYFELQ STFVDNTTFV TDRVTVHSDE TEQIRPIIRE KVLLDESLGE VDTVKCPSPT
     DTLGESEVGS SGSSPGEVLI NSDLEDGYRG GSELRESMIQ TLEKRREKLK ESELQELKES
     IEGGVKPEEP EVPNESDIMK CAKLNEETVV DDYTVVVRRS SGSSVTRSHS VIETGRKNSG
     GETGAMVQKS DVIKELAQVI TEENGLKSVL NGKKGCEEEE EIAGANQNSN FKISTYNGLH
     KDSLVAAPVE EKPISAPASQ KSDSEEENVI VRRKISADSI LRSKLSSDED EAKTSYQSSA
     KKEGGGPVKR RSLTVLNKSP KNINRSDSFH STRSDYIQSL ASNGLRLTPR STSYISLIGA
     QKFENRFAQS NRRKSTSEMS ICDSPSLQSL QVIKNILNTS RSNLAAAAHG DKKEGEEEEQ
     QQQELLPMAA IKRNSFTDIS TLVQFKSEVV RSGLTRRESL VERKIEEVET VKSVDEEDDL
     KKEVEKLDDL VSTKISEKLE PLFDVSNESK SDDEKLQNKQ LTATVTKQAQ TTVVNITTTS
     TTVAHSGVTV NGGQNSAINE QKWKYQGPPT INLTTWSERP KIDVSIKSDR DYRFGGSSTL
     PRGYRNVNNT TKININAPSA PASEKDDGYD CPDSREQVPL SSGEAQAFSL PQEVNRPEPV
     SITSITTTDR LPIVRAVEYK KNIVPPPVVA QKPEKSYFYE TFSRTAAPQP SGTATINRLS
     LGYQKFQPVV RGFKSMDEKD LAPRQRPVSM IESTNISTAI LRSTPVRAEK PPAPEVATSL
     PFGQNTLRRT GLKDKILAQT AAEPPKATPQ EPVIVPLKAT PVAAVVPPPP PPKMTTPVVR
     AAIVKRPLPP LAQADPRSAL LDAIRGFNKD KLRKEATAE
//