ID B0WQX2_CULQU Unreviewed; 215 AA.
AC B0WQX2;
DT 08-APR-2008, integrated into UniProtKB/TrEMBL.
DT 08-APR-2008, sequence version 1.
DT 24-JAN-2024, entry version 82.
DE RecName: Full=Methyltransferase-like protein 5 {ECO:0000256|ARBA:ARBA00041374};
GN Name=6041916 {ECO:0000313|EnsemblMetazoa:CPIJ009437-PA};
GN ORFNames=CpipJ_CPIJ009437 {ECO:0000313|EMBL:EDS33052.1};
OS Culex quinquefasciatus (Southern house mosquito) (Culex pungens).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Culicini; Culex; Culex.
OX NCBI_TaxID=7176;
RN [1] {ECO:0000313|EMBL:EDS33052.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JHB {ECO:0000313|EMBL:EDS33052.1};
RG The Broad Institute Genome Sequencing Platform;
RA Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.,
RA Hannick L., Megy K., O'Leary S., Pearson M., Haas B.J., Mauceli E.,
RA Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L., Amedeo P.,
RA Antoine C.H., Arensburger P., Bidwell S.L., Crawford M., Camaro F.,
RA Devon K., Engels R., Hammond M., Howarth C., Koehrsen M., Lawson D.,
RA Montgomery P., Nene V., Nusbaum C., Puiu D., Romero-Severson J.,
RA Severson D.W., Shumway M., Sisk P., Stolte C., Zeng Q., Eisenstadt E.,
RA Fraser-Liggett C., Strausberg R., Galagan J., Birren B., Collins F.H.;
RT "Annotation of Culex pipiens quinquefasciatus.";
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:CPIJ009437-PA}
RP IDENTIFICATION.
RC STRAIN=JHB {ECO:0000313|EnsemblMetazoa:CPIJ009437-PA};
RG EnsemblMetazoa;
RL Submitted (FEB-2021) to UniProtKB.
CC -!- SIMILARITY: Belongs to the methyltransferase superfamily. PrmA family.
CC {ECO:0000256|ARBA:ARBA00009741}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; DS232046; EDS33052.1; -; Genomic_DNA.
DR RefSeq; XP_001851106.1; XM_001851054.1.
DR AlphaFoldDB; B0WQX2; -.
DR STRING; 7176.B0WQX2; -.
DR EnsemblMetazoa; CPIJ009437-RA; CPIJ009437-PA; CPIJ009437.
DR KEGG; cqu:CpipJ_CPIJ009437; -.
DR VEuPathDB; VectorBase:CPIJ009437; -.
DR eggNOG; KOG3420; Eukaryota.
DR HOGENOM; CLU_074702_1_1_1; -.
DR InParanoid; B0WQX2; -.
DR OMA; DVVYSIH; -.
DR Proteomes; UP000002320; Unassembled WGS sequence.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0000179; F:rRNA (adenine-N6,N6-)-dimethyltransferase activity; IEA:InterPro.
DR GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR InterPro; IPR020596; rRNA_Ade_Mease_Trfase_CS.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR007848; Small_mtfrase_dom.
DR PANTHER; PTHR23290:SF0; RRNA N6-ADENOSINE-METHYLTRANSFERASE METTL5; 1.
DR PANTHER; PTHR23290; UNCHARACTERIZED; 1.
DR Pfam; PF05175; MTS; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS00092; N6_MTASE; 1.
DR PROSITE; PS01131; RRNA_A_DIMETH; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000313|EMBL:EDS33052.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000002320};
KW Transferase {ECO:0000313|EMBL:EDS33052.1};
KW tRNA processing {ECO:0000256|ARBA:ARBA00022694}.
FT DOMAIN 51..144
FT /note="Methyltransferase small"
FT /evidence="ECO:0000259|Pfam:PF05175"
SQ SEQUENCE 215 AA; 24417 MW; 329EBA402CA3C651 CRC64;
MACLKLKKFE EFLQTVEGFE KPKVYLEQYV TPSHIAAHAL YTIETNYGDL ENKLVLDLGC
GPGMLSIGAA LLGAQHVVGI EIDLDAIKVF QENVQGFELE NVDCVQWDVL NLDGLYDILK
FDTVLMNPPF GTKQNNGIDM NFLRIALKLA KQSVYSLHKT STRDHIKKKA VEWNVKACVV
AELKYNLPQT YKFQKRTSVD IAVDLWRFDV SKRNC
//
