ID B0WRF9_CULQU Unreviewed; 373 AA.
AC B0WRF9;
DT 08-APR-2008, integrated into UniProtKB/TrEMBL.
DT 08-APR-2008, sequence version 1.
DT 27-MAR-2024, entry version 85.
DE SubName: Full=Setd1a protein {ECO:0000313|EMBL:EDS33352.1, ECO:0000313|EnsemblMetazoa:CPIJ009853-PA};
GN Name=6042145 {ECO:0000313|EnsemblMetazoa:CPIJ009853-PA};
GN ORFNames=CpipJ_CPIJ009853 {ECO:0000313|EMBL:EDS33352.1};
OS Culex quinquefasciatus (Southern house mosquito) (Culex pungens).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Culicini; Culex; Culex.
OX NCBI_TaxID=7176;
RN [1] {ECO:0000313|EMBL:EDS33352.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JHB {ECO:0000313|EMBL:EDS33352.1};
RG The Broad Institute Genome Sequencing Platform;
RA Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.,
RA Hannick L., Megy K., O'Leary S., Pearson M., Haas B.J., Mauceli E.,
RA Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L., Amedeo P.,
RA Antoine C.H., Arensburger P., Bidwell S.L., Crawford M., Camaro F.,
RA Devon K., Engels R., Hammond M., Howarth C., Koehrsen M., Lawson D.,
RA Montgomery P., Nene V., Nusbaum C., Puiu D., Romero-Severson J.,
RA Severson D.W., Shumway M., Sisk P., Stolte C., Zeng Q., Eisenstadt E.,
RA Fraser-Liggett C., Strausberg R., Galagan J., Birren B., Collins F.H.;
RT "Annotation of Culex pipiens quinquefasciatus.";
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:CPIJ009853-PA}
RP IDENTIFICATION.
RC STRAIN=JHB {ECO:0000313|EnsemblMetazoa:CPIJ009853-PA};
RG EnsemblMetazoa;
RL Submitted (FEB-2021) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; DS232055; EDS33352.1; -; Genomic_DNA.
DR RefSeq; XP_001851293.1; XM_001851241.1.
DR AlphaFoldDB; B0WRF9; -.
DR STRING; 7176.B0WRF9; -.
DR EnsemblMetazoa; CPIJ009853-RA; CPIJ009853-PA; CPIJ009853.
DR KEGG; cqu:CpipJ_CPIJ009853; -.
DR VEuPathDB; VectorBase:CPIJ009853; -.
DR VEuPathDB; VectorBase:CQUJHB005603; -.
DR eggNOG; KOG1080; Eukaryota.
DR HOGENOM; CLU_045885_0_0_1; -.
DR InParanoid; B0WRF9; -.
DR OrthoDB; 5527044at2759; -.
DR Proteomes; UP000002320; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0042800; F:histone H3K4 methyltransferase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR Gene3D; 2.170.270.10; SET domain; 1.
DR InterPro; IPR044570; Set1-like.
DR InterPro; IPR001214; SET_dom.
DR InterPro; IPR046341; SET_dom_sf.
DR PANTHER; PTHR45814; HISTONE-LYSINE N-METHYLTRANSFERASE SETD1; 1.
DR PANTHER; PTHR45814:SF2; HISTONE-LYSINE N-METHYLTRANSFERASE SETD1; 1.
DR Pfam; PF00856; SET; 1.
DR SMART; SM00317; SET; 1.
DR SUPFAM; SSF82199; SET domain; 1.
DR PROSITE; PS50280; SET; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Reference proteome {ECO:0000313|Proteomes:UP000002320};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 175..362
FT /note="SET"
FT /evidence="ECO:0000259|PROSITE:PS50280"
FT REGION 82..115
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 202..272
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 251..271
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 373 AA; 41457 MW; 58EEE0ABF2ECBE3F CRC64;
MDVVESSLMK EYVILSLIQN SFIHNTVLCC LVCLYSSLGV PDRGKTRWPS PNYSTVKGGV
YQVAFDLSET ATHQFLPMEV QQQQQPTATE VAPVVPTQRS AGRPKEDPNA PKAKYKKDKA
AAVAVATLQT FAAAAATFSS AAVHVHARPK YHERDIRTQM SMLYNFLSRG FDAEDGQYIR
QSYEHQTALD LVSANAKLLQ DIPAGKGHIP PSVRYGSRKP PEEHRNGQGR HQDAGSSARS
PIELAPAPSP ICSSSAKTSS SLPNRQSTTI YDGIDRCRRD GHRVVRPSVT DLREIKYEAI
GISSTYLFRI DMETIIDASN YGNLARFINH SCNPNCYTKV ITIELEKKIP IGVNKEITYD
YKVPLEDEKI SFY
//
