ID B0WZE4_CULQU Unreviewed; 276 AA.
AC B0WZE4;
DT 08-APR-2008, integrated into UniProtKB/TrEMBL.
DT 08-APR-2008, sequence version 1.
DT 27-MAR-2024, entry version 82.
DE SubName: Full=Trypsin {ECO:0000313|EMBL:EDS37458.1, ECO:0000313|EnsemblMetazoa:CPIJ012152-PA};
GN Name=6045388 {ECO:0000313|EnsemblMetazoa:CPIJ012152-PA};
GN ORFNames=CpipJ_CPIJ012152 {ECO:0000313|EMBL:EDS37458.1};
OS Culex quinquefasciatus (Southern house mosquito) (Culex pungens).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Culicini; Culex; Culex.
OX NCBI_TaxID=7176;
RN [1] {ECO:0000313|EMBL:EDS37458.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JHB {ECO:0000313|EMBL:EDS37458.1};
RG The Broad Institute Genome Sequencing Platform;
RA Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.,
RA Hannick L., Megy K., O'Leary S., Pearson M., Haas B.J., Mauceli E.,
RA Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L., Amedeo P.,
RA Antoine C.H., Arensburger P., Bidwell S.L., Crawford M., Camaro F.,
RA Devon K., Engels R., Hammond M., Howarth C., Koehrsen M., Lawson D.,
RA Montgomery P., Nene V., Nusbaum C., Puiu D., Romero-Severson J.,
RA Severson D.W., Shumway M., Sisk P., Stolte C., Zeng Q., Eisenstadt E.,
RA Fraser-Liggett C., Strausberg R., Galagan J., Birren B., Collins F.H.;
RT "Annotation of Culex pipiens quinquefasciatus.";
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:CPIJ012152-PA}
RP IDENTIFICATION.
RC STRAIN=JHB {ECO:0000313|EnsemblMetazoa:CPIJ012152-PA};
RG EnsemblMetazoa;
RL Submitted (FEB-2021) to UniProtKB.
CC -!- SIMILARITY: Belongs to the peptidase S1 family. CLIP subfamily.
CC {ECO:0000256|ARBA:ARBA00024195}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; DS232206; EDS37458.1; -; Genomic_DNA.
DR RefSeq; XP_001862766.1; XM_001862731.1.
DR AlphaFoldDB; B0WZE4; -.
DR STRING; 7176.B0WZE4; -.
DR EnsemblMetazoa; CPIJ012152-RA; CPIJ012152-PA; CPIJ012152.
DR GeneID; 6045388; -.
DR KEGG; cqu:CpipJ_CPIJ012152; -.
DR VEuPathDB; VectorBase:CPIJ012152; -.
DR VEuPathDB; VectorBase:CQUJHB017131; -.
DR eggNOG; KOG3627; Eukaryota.
DR HOGENOM; CLU_006842_7_0_1; -.
DR InParanoid; B0WZE4; -.
DR OMA; MINPFWL; -.
DR OrthoDB; 3468962at2759; -.
DR Proteomes; UP000002320; Unassembled WGS sequence.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR CDD; cd00190; Tryp_SPc; 1.
DR Gene3D; 2.40.10.10; Trypsin-like serine proteases; 1.
DR InterPro; IPR009003; Peptidase_S1_PA.
DR InterPro; IPR043504; Peptidase_S1_PA_chymotrypsin.
DR InterPro; IPR001314; Peptidase_S1A.
DR InterPro; IPR001254; Trypsin_dom.
DR PANTHER; PTHR24276:SF99; AQUARIUS-RELATED; 1.
DR PANTHER; PTHR24276; POLYSERASE-RELATED; 1.
DR Pfam; PF00089; Trypsin; 1.
DR PRINTS; PR00722; CHYMOTRYPSIN.
DR SMART; SM00020; Tryp_SPc; 1.
DR SUPFAM; SSF50494; Trypsin-like serine proteases; 1.
DR PROSITE; PS50240; TRYPSIN_DOM; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Reference proteome {ECO:0000313|Proteomes:UP000002320};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 18..276
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5011408957"
FT DOMAIN 26..262
FT /note="Peptidase S1"
FT /evidence="ECO:0000259|PROSITE:PS50240"
SQ SEQUENCE 276 AA; 29586 MW; 9781D6229206CFA2 CRC64;
MKLFVFALLA LATVAFASEG APAGRLAGGA LTLPGQHPSV VSIDSPYNLH CGGTIINLQH
VLTAAWCVMH PTTFTLINPF WLRVIAGDVN LVPTSIRREV RSVTHLFVHP NYNRLSGNND
LAVMRVNTPF PEFHNTIEPA VINTRVLADN TQCQYIGWGA PTNAANAPLN PAQRMIQVPT
LAPAQCNVAN VHNNRVLSTM ICAGSIPANA NTVCQGNIGG GLFCNGQLTG VLSFGLACGA
ANQPGVYIDV RQYRQWIDTQ FTRTDSPPPG WAPIPM
//
