ID B0WZZ9_CULQU Unreviewed; 258 AA.
AC B0WZZ9;
DT 08-APR-2008, integrated into UniProtKB/TrEMBL.
DT 08-APR-2008, sequence version 1.
DT 24-JAN-2024, entry version 77.
DE SubName: Full=Pyruvate carboxylase {ECO:0000313|EMBL:EDS37874.1, ECO:0000313|EnsemblMetazoa:CPIJ012791-PA};
GN Name=6045649 {ECO:0000313|EnsemblMetazoa:CPIJ012791-PA};
GN ORFNames=CpipJ_CPIJ012791 {ECO:0000313|EMBL:EDS37874.1};
OS Culex quinquefasciatus (Southern house mosquito) (Culex pungens).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Culicini; Culex; Culex.
OX NCBI_TaxID=7176;
RN [1] {ECO:0000313|EMBL:EDS37874.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JHB {ECO:0000313|EMBL:EDS37874.1};
RG The Broad Institute Genome Sequencing Platform;
RA Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.,
RA Hannick L., Megy K., O'Leary S., Pearson M., Haas B.J., Mauceli E.,
RA Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L., Amedeo P.,
RA Antoine C.H., Arensburger P., Bidwell S.L., Crawford M., Camaro F.,
RA Devon K., Engels R., Hammond M., Howarth C., Koehrsen M., Lawson D.,
RA Montgomery P., Nene V., Nusbaum C., Puiu D., Romero-Severson J.,
RA Severson D.W., Shumway M., Sisk P., Stolte C., Zeng Q., Eisenstadt E.,
RA Fraser-Liggett C., Strausberg R., Galagan J., Birren B., Collins F.H.;
RT "Annotation of Culex pipiens quinquefasciatus.";
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:CPIJ012791-PA}
RP IDENTIFICATION.
RC STRAIN=JHB {ECO:0000313|EnsemblMetazoa:CPIJ012791-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; DS232223; EDS37874.1; -; Genomic_DNA.
DR RefSeq; XP_001862971.1; XM_001862936.1.
DR AlphaFoldDB; B0WZZ9; -.
DR STRING; 7176.B0WZZ9; -.
DR EnsemblMetazoa; CPIJ012791-RA; CPIJ012791-PA; CPIJ012791.
DR KEGG; cqu:CpipJ_CPIJ012791; -.
DR VEuPathDB; VectorBase:CPIJ012791; -.
DR VEuPathDB; VectorBase:CQUJHB014683; -.
DR eggNOG; KOG0369; Eukaryota.
DR HOGENOM; CLU_1078711_0_0_1; -.
DR InParanoid; B0WZZ9; -.
DR OrthoDB; 1129179at2759; -.
DR Proteomes; UP000002320; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004736; F:pyruvate carboxylase activity; IEA:InterPro.
DR GO; GO:0006094; P:gluconeogenesis; IEA:InterPro.
DR GO; GO:0006090; P:pyruvate metabolic process; IEA:InterPro.
DR Gene3D; 3.40.50.20; -; 1.
DR Gene3D; 3.30.1490.20; ATP-grasp fold, A domain; 1.
DR Gene3D; 3.30.470.20; ATP-grasp fold, B domain; 1.
DR InterPro; IPR013815; ATP_grasp_subdomain_1.
DR InterPro; IPR005479; CbamoylP_synth_lsu-like_ATP-bd.
DR InterPro; IPR016185; PreATP-grasp_dom_sf.
DR InterPro; IPR005930; Pyruv_COase.
DR PANTHER; PTHR43778; PYRUVATE CARBOXYLASE; 1.
DR PANTHER; PTHR43778:SF2; PYRUVATE CARBOXYLASE, MITOCHONDRIAL; 1.
DR Pfam; PF02786; CPSase_L_D2; 1.
DR SUPFAM; SSF56059; Glutathione synthetase ATP-binding domain-like; 1.
DR SUPFAM; SSF52440; PreATP-grasp domain; 1.
PE 4: Predicted;
KW Pyruvate {ECO:0000313|EMBL:EDS37874.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000002320}.
FT DOMAIN 149..258
FT /note="Carbamoyl-phosphate synthetase large subunit-like
FT ATP-binding"
FT /evidence="ECO:0000259|Pfam:PF02786"
SQ SEQUENCE 258 AA; 28188 MW; C57F71FA9EF0B265 CRC64;
MLCFLNFVLR SLKSKPYQGL EGKPVPVAGS SPSDGILLKR SAASAASKLV ETHPVRAGCE
PRRNRYRVFL VCNELGMPSV AIYSEQNRQH MHRQKADESY IDSKGLAPVE VCNTFQKLSG
CARRTTSTTC TLVKGHIGPS PKVVQQMGDK VAARKAAIEA GVLILPETDG PVIIKVEVLV
FCKKHGFPVI FKAASSGKVG DNFERGSSEA KASVGNGAML IGRFIERPRH IELQLLDDKA
GNVDHLYERD GPVERRHQ
//
