ID B0X4T7_CULQU Unreviewed; 285 AA.
AC B0X4T7;
DT 08-APR-2008, integrated into UniProtKB/TrEMBL.
DT 08-APR-2008, sequence version 1.
DT 27-MAR-2024, entry version 86.
DE SubName: Full=Receptor for tachykinin-like peptides {ECO:0000313|EMBL:EDS40552.1, ECO:0000313|EnsemblMetazoa:CPIJ014103-PA};
GN Name=6047624 {ECO:0000313|EnsemblMetazoa:CPIJ014103-PA};
GN ORFNames=CpipJ_CPIJ014103 {ECO:0000313|EMBL:EDS40552.1};
OS Culex quinquefasciatus (Southern house mosquito) (Culex pungens).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Culicinae; Culicini; Culex; Culex.
OX NCBI_TaxID=7176;
RN [1] {ECO:0000313|EMBL:EDS40552.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JHB {ECO:0000313|EMBL:EDS40552.1};
RG The Broad Institute Genome Sequencing Platform;
RA Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.,
RA Hannick L., Megy K., O'Leary S., Pearson M., Haas B.J., Mauceli E.,
RA Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L., Amedeo P.,
RA Antoine C.H., Arensburger P., Bidwell S.L., Crawford M., Camaro F.,
RA Devon K., Engels R., Hammond M., Howarth C., Koehrsen M., Lawson D.,
RA Montgomery P., Nene V., Nusbaum C., Puiu D., Romero-Severson J.,
RA Severson D.W., Shumway M., Sisk P., Stolte C., Zeng Q., Eisenstadt E.,
RA Fraser-Liggett C., Strausberg R., Galagan J., Birren B., Collins F.H.;
RT "Annotation of Culex pipiens quinquefasciatus.";
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:CPIJ014103-PA}
RP IDENTIFICATION.
RC STRAIN=JHB {ECO:0000313|EnsemblMetazoa:CPIJ014103-PA};
RG EnsemblMetazoa;
RL Submitted (FEB-2021) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC {ECO:0000256|ARBA:ARBA00010663}.
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DR EMBL; DS232352; EDS40552.1; -; Genomic_DNA.
DR RefSeq; XP_001864659.1; XM_001864624.1.
DR AlphaFoldDB; B0X4T7; -.
DR STRING; 7176.B0X4T7; -.
DR EnsemblMetazoa; CPIJ014103-RA; CPIJ014103-PA; CPIJ014103.
DR KEGG; cqu:CpipJ_CPIJ014103; -.
DR VEuPathDB; VectorBase:CPIJ014103; -.
DR VEuPathDB; VectorBase:CQUJHB010424; -.
DR eggNOG; KOG4219; Eukaryota.
DR HOGENOM; CLU_977456_0_0_1; -.
DR InParanoid; B0X4T7; -.
DR OMA; FYHSHAT; -.
DR OrthoDB; 2912851at2759; -.
DR Proteomes; UP000002320; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004995; F:tachykinin receptor activity; IEA:InterPro.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR InterPro; IPR001681; Neurokn_rcpt.
DR PANTHER; PTHR46925; G-PROTEIN COUPLED RECEPTOR TKR-1-RELATED; 1.
DR PANTHER; PTHR46925:SF2; G-PROTEIN COUPLED RECEPTOR TKR-1-RELATED; 1.
DR Pfam; PF00001; 7tm_1; 1.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000313|EMBL:EDS40552.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000002320};
KW Transducer {ECO:0000256|ARBA:ARBA00023224};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..45
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 65..83
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..80
FT /note="G-protein coupled receptors family 1 profile"
FT /evidence="ECO:0000259|PROSITE:PS50262"
FT REGION 229..285
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 229..254
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 270..285
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 285 AA; 31826 MW; FC5805A30E8C373F CRC64;
MAGRKKIRGS FVEKCKFKSK VVRMFIIVVT IFAICWLPYH LFFVYAYHNN QMTSSSYVQQ
LYLGFYWLAM SNAMVNPIIY YWMNSRFRVY FQEIICFCCL QFLNSRMKDG MPPGVLLNKN
SNSELGRYRS YRQRSLSVRW RPQFHSTEEY RMRLAAPQRN HHLSNSHGPC HRTVSVVNVL
ENNGKAAGLD HLSAVAGAGG GGGIDPKSTA ATDIGSELQA LNFLPRSHNH SNQFYHSHAT
SHHSSHSQDS HVSSGGGGGG VGGKFGSSGQ VAKDGSSSSH SQEYS
//
