ID   B0XC09_CULQU            Unreviewed;      1023 AA.
AC   B0XC09;
DT   08-APR-2008, integrated into UniProtKB/TrEMBL.
DT   08-APR-2008, sequence version 1.
DT   24-JAN-2024, entry version 77.
DE   SubName: Full=Ribosome biogenesis protein {ECO:0000313|EMBL:EDS44572.1, ECO:0000313|EnsemblMetazoa:CPIJ016808-PA};
GN   Name=6050599 {ECO:0000313|EnsemblMetazoa:CPIJ016808-PA};
GN   ORFNames=CpipJ_CPIJ016808 {ECO:0000313|EMBL:EDS44572.1};
OS   Culex quinquefasciatus (Southern house mosquito) (Culex pungens).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Culicinae; Culicini; Culex; Culex.
OX   NCBI_TaxID=7176;
RN   [1] {ECO:0000313|EMBL:EDS44572.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JHB {ECO:0000313|EMBL:EDS44572.1};
RG   The Broad Institute Genome Sequencing Platform;
RA   Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.,
RA   Hannick L., Megy K., O'Leary S., Pearson M., Haas B.J., Mauceli E.,
RA   Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L., Amedeo P.,
RA   Antoine C.H., Arensburger P., Bidwell S.L., Crawford M., Camaro F.,
RA   Devon K., Engels R., Hammond M., Howarth C., Koehrsen M., Lawson D.,
RA   Montgomery P., Nene V., Nusbaum C., Puiu D., Romero-Severson J.,
RA   Severson D.W., Shumway M., Sisk P., Stolte C., Zeng Q., Eisenstadt E.,
RA   Fraser-Liggett C., Strausberg R., Galagan J., Birren B., Collins F.H.;
RT   "Annotation of Culex pipiens quinquefasciatus.";
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:CPIJ016808-PA}
RP   IDENTIFICATION.
RC   STRAIN=JHB {ECO:0000313|EnsemblMetazoa:CPIJ016808-PA};
RG   EnsemblMetazoa;
RL   Submitted (FEB-2021) to UniProtKB.
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DR   EMBL; DS232667; EDS44572.1; -; Genomic_DNA.
DR   RefSeq; XP_001867181.1; XM_001867146.1.
DR   AlphaFoldDB; B0XC09; -.
DR   STRING; 7176.B0XC09; -.
DR   EnsemblMetazoa; CPIJ016808-RA; CPIJ016808-PA; CPIJ016808.
DR   KEGG; cqu:CpipJ_CPIJ016808; -.
DR   VEuPathDB; VectorBase:CPIJ016808; -.
DR   VEuPathDB; VectorBase:CQUJHB017448; -.
DR   eggNOG; KOG1951; Eukaryota.
DR   HOGENOM; CLU_295653_0_0_1; -.
DR   InParanoid; B0XC09; -.
DR   OMA; QNEDSEA; -.
DR   OrthoDB; 5478101at2759; -.
DR   Proteomes; UP000002320; Unassembled WGS sequence.
DR   GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR   GO; GO:0042254; P:ribosome biogenesis; IEA:InterPro.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR039761; Bms1/Tsr1.
DR   InterPro; IPR007034; BMS1_TSR1_C.
DR   InterPro; IPR006073; GTP-bd.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR12858; RIBOSOME BIOGENESIS PROTEIN; 1.
DR   PANTHER; PTHR12858:SF2; RIBOSOME BIOGENESIS PROTEIN BMS1 HOMOLOG; 1.
DR   Pfam; PF01926; MMR_HSR1; 1.
DR   Pfam; PF04950; RIBIOP_C; 1.
DR   SMART; SM01362; DUF663; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000002320}.
FT   DOMAIN          274..574
FT                   /note="Ribosome biogenesis protein BMS1/TSR1 C-terminal"
FT                   /evidence="ECO:0000259|SMART:SM01362"
FT   REGION          1..42
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          234..272
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          642..664
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          691..711
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        238..272
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        644..664
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1023 AA;  115086 MW;  1872B942CA743261 CRC64;
     MADDGNFAEK QKTHKKRHAG VKADKKKAKN KPTDKGKNVK AFAITKARSA EKRFRRKEDI
     LTKKQHIPLV DKTPEEPPPV LIAVVGPPKV GKSTLINNLI KNFTRTNVTS VNGPITIITS
     KKRRITLIEC NNDINSMIDV PSARNAEDYG RADPFGTRSR SAKAVKMQKK VLKHRFWTEV
     YDGAKLFYLS GLIHGEYLRN EITNLGRFIS WKASEDAEEL LKLDDMSDGD SEVFGDFEDL
     ETGEKHEGKV EEKEEGESKE DENSKKRKLS RIEEKNMSRT ELMAKKMKLK AKFDSEYDNP
     EKDDQHIEGD HKYYEKLKAD ALRQSELNKK EFSNLDEDIR LNIEGYRAGL YVRMNFTNVP
     YEFVEHFDPA FPVLIGGLNM AEENVGFVSC KVKKHRWYKK ILKAGDPLII SLGWRRFQTI
     PIFAKVEDDL KHRYLKYTPN HVTCSMTFWG PITPQNTGVL AIQSIAYDPQ ETKRLGFRVA
     ATGAVSESDK SAQIMKKLKL IGTPYKIYNK TAFIQGMFNS TLEVAKFEGA KIKTVSGIRG
     QIKKAVPPDG SFRATFEDRI VLSDIVFCRT WFKVTVPNFY APVTNLLLPP QKKAKWVGMK
     TLGQLKKDKD IHFEAVPDSS YKPIVREDLQ FRPLVIPKNL QKALPYKDKP KHAPQKSKTK
     SLQDERIAVV HSPHEQKVAK MMKMIRTNYE AGEERRKAQA KQKSEKYKKQ KTNENFRKLQ
     RQKELKKKVF KAISKMEAKH QSKAAKGSRI SAILIKLPPT STCFFPDTVG GSSADVGPLS
     YACRCSASGS PEPTSGRLVL LLAGLGVDVE LTGVPASLWL LLQTSLSPSC ACPSRPRVVL
     WVACGSEGSK MEDADDLAMP ASRCSSIPQL TTVDGDAHGH GCWGGTTTEP GDSPLSSVKS
     FDRFLALALH NTPSSCSRSY DGFRDLSHFN TPGKWPMKIR ASSREPLIRR ILENPPIIII
     SFATPNGRPF VDPRPSGNFW PNSSHLPISF NVNTTHQQKF STCRTAECFT QVNAEDDVIR
     AGV
//