ID B1A1N5_DROME Unreviewed; 122 AA.
AC B1A1N5;
DT 08-APR-2008, integrated into UniProtKB/TrEMBL.
DT 08-APR-2008, sequence version 1.
DT 24-JAN-2024, entry version 66.
DE RecName: Full=histone acetyltransferase {ECO:0000256|ARBA:ARBA00013184};
DE EC=2.3.1.48 {ECO:0000256|ARBA:ARBA00013184};
DE Flags: Fragment;
GN Name=chm {ECO:0000313|EMBL:ACA01348.1};
OS Drosophila melanogaster (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=7227 {ECO:0000313|EMBL:ACA01348.1};
RN [1] {ECO:0000313|EMBL:ACA01348.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=18245821; DOI=10.1534/genetics.107.085423;
RA Levine M.T., Begun D.J.;
RT "Evidence of spatially varying selection acting on four chromatin-
RT remodeling loci in Drosophila melanogaster.";
RL Genetics 179:475-485(2008).
CC -!- SIMILARITY: Belongs to the MYST (SAS/MOZ) family.
CC {ECO:0000256|ARBA:ARBA00010107}.
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DR EMBL; EU415908; ACA01348.1; -; Genomic_DNA.
DR VEuPathDB; VectorBase:FBgn0028387; -.
DR HOGENOM; CLU_011815_5_0_1; -.
DR ExpressionAtlas; B1A1N5; baseline and differential.
DR GO; GO:0004402; F:histone acetyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR InterPro; IPR002717; HAT_MYST-type.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR10615; HISTONE ACETYLTRANSFERASE; 1.
DR PANTHER; PTHR10615:SF210; HISTONE ACETYLTRANSFERASE KAT7; 1.
DR Pfam; PF01853; MOZ_SAS; 1.
DR SUPFAM; SSF55729; Acyl-CoA N-acyltransferases (Nat); 1.
DR PROSITE; PS51726; MYST_HAT; 1.
PE 3: Inferred from homology;
KW Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 1..112
FT /note="MYST-type HAT"
FT /evidence="ECO:0000259|PROSITE:PS51726"
FT ACT_SITE 14
FT /note="Proton donor/acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR602717-51"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ACA01348.1"
SQ SEQUENCE 122 AA; 14104 MW; 37E8661E3EEA78B3 CRC64;
YLLTRVEGKI GSPEKPLSDL GLISYRSYWK DVLLDYLCNR SGNTIAIKDV SQETAIYSYD
IVSTLQALGM MKYWXGKHIV LKKQDVLDEY EERVKRRGTF PKIDDSCLRW QPFINIQPSS
SP
//
