ID B1LSE2_METRJ Unreviewed; 579 AA.
AC B1LSE2;
DT 29-APR-2008, integrated into UniProtKB/TrEMBL.
DT 29-APR-2008, sequence version 1.
DT 27-MAR-2024, entry version 79.
DE SubName: Full=Methyl-accepting chemotaxis sensory transducer {ECO:0000313|EMBL:ACB23823.1};
GN OrderedLocusNames=Mrad2831_1828 {ECO:0000313|EMBL:ACB23823.1};
OS Methylobacterium radiotolerans (strain ATCC 27329 / DSM 1819 / JCM 2831 /
OS NBRC 15690 / NCIMB 10815 / 0-1).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Methylobacteriaceae; Methylobacterium.
OX NCBI_TaxID=426355 {ECO:0000313|EMBL:ACB23823.1, ECO:0000313|Proteomes:UP000006589};
RN [1] {ECO:0000313|EMBL:ACB23823.1, ECO:0000313|Proteomes:UP000006589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 27329 / DSM 1819 / JCM 2831 / NBRC 15690 / NCIMB 10815 /
RC 0-1 {ECO:0000313|Proteomes:UP000006589};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Kiss H., Brettin T., Detter J.C., Han C.,
RA Kuske C.R., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N.,
RA Mikhailova N., Marx C.J., Richardson P.;
RT "Complete sequence of chromosome of Methylobacterium radiotolerans JCM
RT 2831.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC family. {ECO:0000256|ARBA:ARBA00029447}.
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DR EMBL; CP001001; ACB23823.1; -; Genomic_DNA.
DR RefSeq; WP_012318809.1; NC_010505.1.
DR AlphaFoldDB; B1LSE2; -.
DR STRING; 426355.Mrad2831_1828; -.
DR KEGG; mrd:Mrad2831_1828; -.
DR PATRIC; fig|426355.14.peg.1881; -.
DR eggNOG; COG0840; Bacteria.
DR HOGENOM; CLU_000445_107_27_5; -.
DR OrthoDB; 8482111at2; -.
DR Proteomes; UP000006589; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR CDD; cd06225; HAMP; 1.
DR Gene3D; 1.10.8.500; HAMP domain in histidine kinase; 1.
DR Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR004089; MCPsignal_dom.
DR InterPro; IPR033480; sCache_2.
DR InterPro; IPR000727; T_SNARE_dom.
DR PANTHER; PTHR32089:SF112; HEME-BASED AEROTACTIC TRANSDUCER HEMAT; 1.
DR PANTHER; PTHR32089; METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPB; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF00015; MCPsignal; 1.
DR Pfam; PF17200; sCache_2; 1.
DR SMART; SM01049; Cache_2; 1.
DR SMART; SM00304; HAMP; 1.
DR SMART; SM00283; MA; 1.
DR SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR PROSITE; PS50885; HAMP; 1.
DR PROSITE; PS50192; T_SNARE; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Methylation {ECO:0000256|ARBA:ARBA00022481};
KW Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|PROSITE-
KW ProRule:PRU00284};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 29..49
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 210..229
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 230..283
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 323..559
FT /note="Methyl-accepting transducer"
FT /evidence="ECO:0000259|PROSITE:PS50111"
FT DOMAIN 475..537
FT /note="T-SNARE coiled-coil homology"
FT /evidence="ECO:0000259|PROSITE:PS50192"
SQ SEQUENCE 579 AA; 60691 MW; 8CB3F76E24F457A5 CRC64;
MTPTQTSRPP ADRAAPWQGF ADLRLRHKLA AVMALVLLAI GALSALSFVD MRGSALEDRA
LMTKRLTEVA QSLLVHYEAQ ARTGQMPVAE AQKAALAAIT ALRFGSEDYF FVLDAQGHLI
ANAFNAKNVG KQVLDQTDVP GGKRYFAEMV ETAKRDGAGF VDYMKPRAGG SVPVEKVASV
QMFKPWGWIV ATGLYRDDVH AAVRDRAITL GLWSAGLALP ILALLLLVGN GLSRPITRLT
AAMRGLADGD LAVTVADQRR GDEVGAMARA VQVFKDALIA KRAADAAAVT ESEAKMRRAQ
MLDDVTARFD AQVSALTQGL SAAAVEMEAT AREMTRTAAR TTDQSVRVAA TSEQTSSNVQ
TVAAASEEMA ASINEIASRV AQSSAMADRA GTDVAQTNAL MQVLSRGTDQ ISEVMGLIAG
IAGQTNLLAL NATIEAARAG EAGKGFAVVA GEVKALASQT ARATETIATQ IAAIQNETRQ
AVESMRTIGG TIEEMRTVAL SVAAAMEEQG AATSEIVRNV TQAAQGTQAV STDIADVRQA
ARETGAASDQ VLSAAQELAR YSTSLGQEVA TFLAAVKAA
//
