ID B1M6J5_METRJ Unreviewed; 409 AA.
AC B1M6J5;
DT 29-APR-2008, integrated into UniProtKB/TrEMBL.
DT 29-APR-2008, sequence version 1.
DT 27-MAR-2024, entry version 76.
DE SubName: Full=Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family {ECO:0000313|EMBL:ACB23655.1};
GN OrderedLocusNames=Mrad2831_1660 {ECO:0000313|EMBL:ACB23655.1};
OS Methylobacterium radiotolerans (strain ATCC 27329 / DSM 1819 / JCM 2831 /
OS NBRC 15690 / NCIMB 10815 / 0-1).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Methylobacteriaceae; Methylobacterium.
OX NCBI_TaxID=426355 {ECO:0000313|EMBL:ACB23655.1, ECO:0000313|Proteomes:UP000006589};
RN [1] {ECO:0000313|EMBL:ACB23655.1, ECO:0000313|Proteomes:UP000006589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 27329 / DSM 1819 / JCM 2831 / NBRC 15690 / NCIMB 10815 /
RC 0-1 {ECO:0000313|Proteomes:UP000006589};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Kiss H., Brettin T., Detter J.C., Han C.,
RA Kuske C.R., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N.,
RA Mikhailova N., Marx C.J., Richardson P.;
RT "Complete sequence of chromosome of Methylobacterium radiotolerans JCM
RT 2831.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- SIMILARITY: Belongs to the UbiH/COQ6 family.
CC {ECO:0000256|ARBA:ARBA00005349}.
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DR EMBL; CP001001; ACB23655.1; -; Genomic_DNA.
DR RefSeq; WP_012318643.1; NC_010505.1.
DR AlphaFoldDB; B1M6J5; -.
DR STRING; 426355.Mrad2831_1660; -.
DR KEGG; mrd:Mrad2831_1660; -.
DR PATRIC; fig|426355.14.peg.1702; -.
DR eggNOG; COG0654; Bacteria.
DR HOGENOM; CLU_009665_8_1_5; -.
DR OrthoDB; 9796623at2; -.
DR UniPathway; UPA00232; -.
DR Proteomes; UP000006589; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR GO; GO:0006744; P:ubiquinone biosynthetic process; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR InterPro; IPR002938; FAD-bd.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR010971; UbiH/COQ6.
DR NCBIfam; TIGR01988; Ubi-OHases; 1.
DR PANTHER; PTHR43876; UBIQUINONE BIOSYNTHESIS MONOOXYGENASE COQ6, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43876:SF7; UBIQUINONE BIOSYNTHESIS MONOOXYGENASE COQ6, MITOCHONDRIAL; 1.
DR Pfam; PF01494; FAD_binding_3; 1.
DR PRINTS; PR00420; RNGMNOXGNASE.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Monooxygenase {ECO:0000256|ARBA:ARBA00023033};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Ubiquinone {ECO:0000313|EMBL:ACB23655.1}.
FT TRANSMEM 12..33
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 15..345
FT /note="FAD-binding"
FT /evidence="ECO:0000259|Pfam:PF01494"
SQ SEQUENCE 409 AA; 42450 MW; 3345553E3B0BFDCF CRC64;
MSEGTRVEEA GAPFAVAVVG AGAAGLAAAL AIARDGIPTA LVGRHAPVAD GRTVALLDGS
VRFLEALGAW EAVAPHASPL CTLQIVDDTG SLFRPPPAQF RAAEIGLDAF GWNVESARLV
ESLRARARAQ DNLTLVEADA AGAVPGETAA RVALADGNAV EARLVVGADG ARSPLRAASG
VRVRDWTYPQ SAITTILAHA RPHRDVSTEF HTRSGPFTLV PLPGGHRSSL VWVTGEGAAR
RLAALDDAAL GQAVERQARA MLGAMRVDGP RGLVPMRGLA VATPVAPRLA LIGEAAHVFP
PIGAQGLNLG LRDAATLRDA VLAAARDRRD PGSRAVLDGY ARARRVDTAA RTAAVDLLNR
SLLSDLLPVD ALRGLGLLAM TQLGPLRRLV MREGVLPQIG APELMRAAR
//
