ID   B1MHP8_MYCA9            Unreviewed;       524 AA.
AC   B1MHP8;
DT   29-APR-2008, integrated into UniProtKB/TrEMBL.
DT   29-APR-2008, sequence version 1.
DT   27-MAR-2024, entry version 76.
DE   SubName: Full=Acyl-CoA synthetase {ECO:0000313|EMBL:CAM64129.1};
GN   OrderedLocusNames=MAB_4055c {ECO:0000313|EMBL:CAM64129.1};
OS   Mycobacteroides abscessus (strain ATCC 19977 / DSM 44196 / CCUG 20993 / CIP
OS   104536 / JCM 13569 / NCTC 13031 / TMC 1543 / L948) (Mycobacterium
OS   abscessus).
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC   Mycobacteroides; Mycobacteroides abscessus.
OX   NCBI_TaxID=561007 {ECO:0000313|EMBL:CAM64129.1, ECO:0000313|Proteomes:UP000007137};
RN   [1] {ECO:0000313|EMBL:CAM64129.1, ECO:0000313|Proteomes:UP000007137}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 19977 / DSM 44196 / CIP 104536 / JCM 13569 / NCTC 13031 /
RC   TMC 1543 {ECO:0000313|Proteomes:UP000007137};
RX   PubMed=19543527; DOI=10.1371/journal.pone.0005660;
RA   Ripoll F., Pasek S., Schenowitz C., Dossat C., Barbe V., Rottman M.,
RA   Macheras E., Heym B., Herrmann J.L., Daffe M., Brosch R., Risler J.L.,
RA   Gaillard J.L.;
RT   "Non mycobacterial virulence genes in the genome of the emerging pathogen
RT   Mycobacterium abscessus.";
RL   PLoS ONE 4:E5660-E5660(2009).
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DR   EMBL; CU458896; CAM64129.1; -; Genomic_DNA.
DR   RefSeq; WP_005094785.1; NZ_MLCG01000001.1.
DR   AlphaFoldDB; B1MHP8; -.
DR   GeneID; 66969489; -.
DR   KEGG; mab:MAB_4055c; -.
DR   Proteomes; UP000007137; Chromosome.
DR   GO; GO:0003824; F:catalytic activity; IEA:UniProt.
DR   Gene3D; 3.30.300.30; -; 1.
DR   Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR   InterPro; IPR025110; AMP-bd_C.
DR   InterPro; IPR045851; AMP-bd_C_sf.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR   InterPro; IPR042099; ANL_N_sf.
DR   PANTHER; PTHR24096:SF149; 4-COUMARATE--COA LIGASE 1-RELATED; 1.
DR   PANTHER; PTHR24096; LONG-CHAIN-FATTY-ACID--COA LIGASE; 1.
DR   Pfam; PF00501; AMP-binding; 1.
DR   Pfam; PF13193; AMP-binding_C; 1.
DR   SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR   PROSITE; PS00455; AMP_BINDING; 1.
PE   4: Predicted;
FT   DOMAIN          30..389
FT                   /note="AMP-dependent synthetase/ligase"
FT                   /evidence="ECO:0000259|Pfam:PF00501"
FT   DOMAIN          440..514
FT                   /note="AMP-binding enzyme C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF13193"
SQ   SEQUENCE   524 AA;  55571 MW;  1DAB935FB09A582E CRC64;
     MTFRSPLPDV SIPDCSVYEY VFGDTGAEDS RIALIDGLTG AQTTLGELRS QIDATAAGLA
     ERGFGIGDVA AVFLPNCSAF AVVLHGILRA GGTASTVNVL YTAEELAKQL IDSKAQLIFT
     VSPLLSRALE AAEIAGIDAA GVITVDPVEG RLSLADIARP DLAPPQVTFD PATHLAVLPY
     SSGTTGKAKG VMLTHHNLVA NIAQAKHLYG VQRGDRVLAV LPFFHIYGLV VLLNVQLKLG
     AELVILPRFE LDTFLGSIAN YRVDHVFVAP PVAVVLAKHP DVDKYDVSCL RSVFSGAAPL
     DEQLGNAVAA RLNCRVSQGY GMTELSPVSH LIPPDRPDIP LNSVGIPVPN SENKIIDTET
     GDEIEIPAEG ESAPGELLVR GPNVMAGYLG NEEATAATIE PDGFLHTGDI AVVRADGVVT
     IVDRLKELIK YKGYQVPPAE LEALLLTHPG IGDAAVIGVP DPSSGEIPKA FVVRTDDDLT
     DEAVMAFVEQ KVAPHKRIRQ VEFIDAIPKS AAGKILRKDL RARI
//