ID B1Y5A4_LEPCP Unreviewed; 474 AA.
AC B1Y5A4;
DT 20-MAY-2008, integrated into UniProtKB/TrEMBL.
DT 20-MAY-2008, sequence version 1.
DT 27-MAR-2024, entry version 73.
DE SubName: Full=Peptidase U62 modulator of DNA gyrase {ECO:0000313|EMBL:ACB33492.1};
DE Flags: Precursor;
GN OrderedLocusNames=Lcho_1223 {ECO:0000313|EMBL:ACB33492.1};
OS Leptothrix cholodnii (strain ATCC 51168 / LMG 8142 / SP-6) (Leptothrix
OS discophora (strain SP-6)).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Sphaerotilaceae; Leptothrix.
OX NCBI_TaxID=395495 {ECO:0000313|EMBL:ACB33492.1, ECO:0000313|Proteomes:UP000001693};
RN [1] {ECO:0000313|EMBL:ACB33492.1, ECO:0000313|Proteomes:UP000001693}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51168 / LMG 8142 / SP-6
RC {ECO:0000313|Proteomes:UP000001693};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C.,
RA Han C., Kuske C.R., Schmutz J., Larimer F., Land M., Hauser L.,
RA Kyrpides N., Lykidis A., Emerson D., Richardson P.;
RT "Complete sequence of Leptothrix cholodnii SP-6.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase U62 family.
CC {ECO:0000256|ARBA:ARBA00005836}.
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DR EMBL; CP001013; ACB33492.1; -; Genomic_DNA.
DR RefSeq; WP_012346254.1; NC_010524.1.
DR AlphaFoldDB; B1Y5A4; -.
DR STRING; 395495.Lcho_1223; -.
DR KEGG; lch:Lcho_1223; -.
DR eggNOG; COG0312; Bacteria.
DR HOGENOM; CLU_026425_0_0_4; -.
DR OrthoDB; 9803618at2; -.
DR Proteomes; UP000001693; Chromosome.
DR GO; GO:0008237; F:metallopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR Gene3D; 3.30.2290.10; PmbA/TldD superfamily; 1.
DR InterPro; IPR045569; Metalloprtase-TldD/E_C.
DR InterPro; IPR045570; Metalloprtase-TldD/E_cen_dom.
DR InterPro; IPR002510; Metalloprtase-TldD/E_N.
DR InterPro; IPR047657; PmbA.
DR InterPro; IPR035068; TldD/PmbA_N.
DR InterPro; IPR036059; TldD/PmbA_sf.
DR PANTHER; PTHR43421; METALLOPROTEASE PMBA; 1.
DR PANTHER; PTHR43421:SF1; METALLOPROTEASE PMBA; 1.
DR Pfam; PF01523; PmbA_TldD_1st; 1.
DR Pfam; PF19290; PmbA_TldD_2nd; 1.
DR Pfam; PF19289; PmbA_TldD_3rd; 1.
DR SUPFAM; SSF111283; Putative modulator of DNA gyrase, PmbA/TldD; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001693}.
FT DOMAIN 55..117
FT /note="Metalloprotease TldD/E N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01523"
FT DOMAIN 148..254
FT /note="Metalloprotease TldD/E central"
FT /evidence="ECO:0000259|Pfam:PF19290"
FT DOMAIN 261..473
FT /note="Metalloprotease TldD/E C-terminal"
FT /evidence="ECO:0000259|Pfam:PF19289"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 474 AA; 50149 MW; DFB615D493B7D2E4 CRC64;
MTTLDSAASS SSSSSASTSN TTSSQGFAYS REQFQQLVED SLALARELGA SDAGVEVSEG
AGLSVSVRKG EIENVERNRD KAIGVTVYIG QRRGNASTSD FAPAALRQTV QAAYDIARFT
AEDSAAGLPD AADLALGDAA VRDLGLFHPW AIDAQTASEI ALRCEAAALS VDKRITNSEG
AAVSAQQSHF FAGNSRGFRG GYSSSRHSLS VSPIAGRGRD MQRDAWYSSM RDALDLSSPE
SVGRYAAERA LSRLKSRKIK TCEVPVLFEA PVAAGLLGAY VNGTSGGSLY RKASFLQDSL
GQAIFPSHID VREDPHIPKG KGSAPFDDEG VLTRARTVVE AGVTLGYFLS SYSARKLGMH
TTGHAGGSQN LTLTSRLTRR GDDLPAMLRK LHRGLFVVEL MGQGVNYVTG DYSRGAAGFW
VENGEIAFPV EEITIAGNLR DMLARIVAVG ADTYNAGSKT MGSVLVERMT IAGH
//
