ID B1Y6A9_LEPCP Unreviewed; 898 AA.
AC B1Y6A9;
DT 20-MAY-2008, integrated into UniProtKB/TrEMBL.
DT 20-MAY-2008, sequence version 1.
DT 27-MAR-2024, entry version 87.
DE SubName: Full=Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S) {ECO:0000313|EMBL:ACB33614.1};
GN OrderedLocusNames=Lcho_1346 {ECO:0000313|EMBL:ACB33614.1};
OS Leptothrix cholodnii (strain ATCC 51168 / LMG 8142 / SP-6) (Leptothrix
OS discophora (strain SP-6)).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Sphaerotilaceae; Leptothrix.
OX NCBI_TaxID=395495 {ECO:0000313|EMBL:ACB33614.1, ECO:0000313|Proteomes:UP000001693};
RN [1] {ECO:0000313|EMBL:ACB33614.1, ECO:0000313|Proteomes:UP000001693}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51168 / LMG 8142 / SP-6
RC {ECO:0000313|Proteomes:UP000001693};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C.,
RA Han C., Kuske C.R., Schmutz J., Larimer F., Land M., Hauser L.,
RA Kyrpides N., Lykidis A., Emerson D., Richardson P.;
RT "Complete sequence of Leptothrix cholodnii SP-6.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP001013; ACB33614.1; -; Genomic_DNA.
DR RefSeq; WP_012346376.1; NC_010524.1.
DR AlphaFoldDB; B1Y6A9; -.
DR STRING; 395495.Lcho_1346; -.
DR KEGG; lch:Lcho_1346; -.
DR eggNOG; COG5000; Bacteria.
DR eggNOG; COG5001; Bacteria.
DR HOGENOM; CLU_000445_70_20_4; -.
DR OrthoDB; 9813903at2; -.
DR Proteomes; UP000001693; Chromosome.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd00130; PAS; 3.
DR Gene3D; 2.10.70.100; -; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 3.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013655; PAS_fold_3.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 2.
DR PANTHER; PTHR44757:SF2; BIOFILM ARCHITECTURE MAINTENANCE PROTEIN MBAA; 1.
DR PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF08447; PAS_3; 1.
DR Pfam; PF13426; PAS_9; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00086; PAC; 3.
DR SMART; SM00091; PAS; 2.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 3.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50113; PAC; 3.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000001693}.
FT DOMAIN 156..208
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 293..345
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 342..388
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 413..467
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 499..632
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 641..895
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
FT COILED 23..68
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 898 AA; 98424 MW; 0609A36A2C6C00C0 CRC64;
MGSLHPTLPA PTAATRCAPL DEAAALRLEI EALRLANAAL ESQLLAGSEQ AESMFVQLER
QRNALRDAHG REQALSAFAQ RVMDTVGGVV IALDPQGRLR QRNRHCQNDL APLPEGSSVD
LLLHPQDLAA LEAALPHLPW QVHSVLFETV RRQGGYRAEH QFAMRDGSYR YHLVEAAMLY
SAQNKEEGAV LSGTDISELK RQEQHLRASD ARFNQAEHVA RVGSWDLVPH TGAMTWSVEM
ARIFDITAQP HASHDAAGAS VYSQADFLAA VHPDERARVV AAQAAASAEH RPCDIEFRIV
TSGGKMKWVH LRSTTFHGDD GRPLRSVGTV QDITERRQAE DEMRLAASVF DNSLNAILIA
DANGRIRKVN RAFTAITGYT AEEAVGDTPR LMKSGLHSPG FYGEMWAELQ ACGKWDGELM
NQCKDGRIIS VRESIAAVHD PAGAVAYYIG IFHDITEQKA SAQRIHQLAY YDVLTGLPNR
ALLMDRCQHE LARAMRDGKR LAVLFLDLDR FKHINDSLGH PVGDGLLRAV AQRLQGTLRD
SDTIARLGGD EFIVLLEHVE TSAGVELAAR RILDAFRDPF QLEEHRLSVG ASVGISLFPD
HASDITSLFK YADLALYQAK AAGRGDFRFF EPRFNDAAKD RMRLERELRQ ALERNQLSLQ
YQPVFALPDG RLAGAEALLR WTHPALGSVS PATFIPIAED SGLIVPIGAW VLEQACRQAR
QWLDAGLDPG VIAVNLSGMQ IQRNDLVDTV SSVLARTGLP ACHLELEISE SYITRHAESD
LQRLGQLRAL GVSMAIDDFG TGQTSLGHLR RLPVSKLKID RSFMADIEHD AAAAAVTRAI
IGLGHGLGLT VVAEGVESAA QESALVAQHC DLVQGFRYAR PLDAPVFAAL CARPQPLR
//
