ID B1YIC0_EXIS2 Unreviewed; 685 AA.
AC B1YIC0;
DT 20-MAY-2008, integrated into UniProtKB/TrEMBL.
DT 20-MAY-2008, sequence version 1.
DT 27-MAR-2024, entry version 91.
DE SubName: Full=ATP-dependent Lon protease {ECO:0000313|EMBL:ACB59803.1};
GN OrderedLocusNames=Exig_0317 {ECO:0000313|EMBL:ACB59803.1};
OS Exiguobacterium sibiricum (strain DSM 17290 / CIP 109462 / JCM 13490 /
OS 255-15).
OC Bacteria; Bacillota; Bacilli; Bacillales;
OC Bacillales Family XII. Incertae Sedis; Exiguobacterium.
OX NCBI_TaxID=262543 {ECO:0000313|EMBL:ACB59803.1, ECO:0000313|Proteomes:UP000001681};
RN [1] {ECO:0000313|EMBL:ACB59803.1, ECO:0000313|Proteomes:UP000001681}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17290 / CIP 109462 / JCM 13490 / 255-15
RC {ECO:0000313|Proteomes:UP000001681};
RX PubMed=16489412; DOI=10.1007/s00792-005-0497-5;
RA Rodrigues D.F., Goris J., Vishnivetskaya T., Gilichinsky D.,
RA Thomashow M.F., Tiedje J.M.;
RT "Characterization of Exiguobacterium isolates from the Siberian permafrost.
RT Description of Exiguobacterium sibiricum sp. nov.";
RL Extremophiles 10:285-294(2006).
RN [2] {ECO:0000313|EMBL:ACB59803.1, ECO:0000313|Proteomes:UP000001681}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17290 / CIP 109462 / JCM 13490 / 255-15
RC {ECO:0000313|Proteomes:UP000001681};
RX PubMed=19019206; DOI=10.1186/1471-2164-9-547;
RA Rodrigues D.F., Ivanova N., He Z., Huebner M., Zhou J., Tiedje J.M.;
RT "Architecture of thermal adaptation in an Exiguobacterium sibiricum strain
RT isolated from 3 million year old permafrost: a genome and transcriptome
RT approach.";
RL BMC Genomics 9:547-547(2008).
RN [3] {ECO:0000313|Proteomes:UP000001681}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17290 / CIP 109462 / JCM 13490 / 255-15
RC {ECO:0000313|Proteomes:UP000001681};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Kiss H., Chertkov O., Monk C.,
RA Brettin T., Detter J.C., Han C., Kuske C.R., Schmutz J., Larimer F.,
RA Land M., Hauser L., Kyrpides N., Mikhailova N., Vishnivetskaya T.,
RA Rodrigues D.F., Gilichinsky D., Tiedje J., Richardson P.;
RT "Complete sequence of chromosome of Exiguobacterium sibiricum 255-15.";
RL Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP001022; ACB59803.1; -; Genomic_DNA.
DR RefSeq; WP_012369228.1; NC_010556.1.
DR AlphaFoldDB; B1YIC0; -.
DR STRING; 262543.Exig_0317; -.
DR KEGG; esi:Exig_0317; -.
DR eggNOG; COG4930; Bacteria.
DR HOGENOM; CLU_023021_1_1_9; -.
DR OrthoDB; 5297084at2; -.
DR Proteomes; UP000001681; Chromosome.
DR GO; GO:0004176; F:ATP-dependent peptidase activity; IEA:InterPro.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 3.30.230.10; -; 1.
DR InterPro; IPR013473; BrxL.
DR InterPro; IPR014061; BrxL-like.
DR InterPro; IPR046838; BrxL_N.
DR InterPro; IPR008269; Lon_proteolytic.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR NCBIfam; TIGR02688; BREX system Lon protease-like protein BrxL; 1.
DR NCBIfam; TIGR02653; Lon_rel_chp; 1.
DR Pfam; PF13337; BrxL_ATPase; 1.
DR Pfam; PF20442; BrxL_N; 1.
DR Pfam; PF05362; Lon_C; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:ACB59803.1};
KW Protease {ECO:0000313|EMBL:ACB59803.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001681}.
FT DOMAIN 20..150
FT /note="BREX system Lon protease-like BrxL N-terminal"
FT /evidence="ECO:0000259|Pfam:PF20442"
FT DOMAIN 522..679
FT /note="Lon proteolytic"
FT /evidence="ECO:0000259|Pfam:PF05362"
SQ SEQUENCE 685 AA; 76668 MW; 219777316C33537F CRC64;
MAEETDGTST LDLDKKLNDI FAGRVVRKDL TKLIKEGANV PVYVLEYLLG MYAATDDEQS
IQEGVDRVKK ILTDNFVRPD ESEKIKSRIR ELGQYSIIDK VTVALNPKID TYEAEFSNLG
LKGVPIPSNF VKEFDKLLVG GIWCMVKIDY YYDEEGRASN PFSVSSLQPI QMPNMDMNEV
FEGRKQFTKN EWIDALIRST GMEPTQLEER VKWHLLLRLV PLVENNYNMC ELGPRGTGKS
HVYKEISPNS ILVSGGQSTV ANLFYNMSTR KVGLVGMWDC VAFDEVAGIR FKDKDGIQIM
KDYMASGSFA RGKEEKNASA SMVFVGNINQ SLDVLLKTSH LFAPFPEEMA NDTAFFDRMH
YYMPGWEIPK MRPDFFTDKY GFIVDYIAEF FREMRKRSFA DSTDRYFKLG NNLNQRDTIA
VRKTVSGMVK LIYPNGIYTK EDIEEILRYA LEGRRRVKEQ LKKIGGMEFY DVMFSYIDKE
TLEEEHVSVP EQGGGKLIPE GMGKSGHIYV VGHGNSGMIG VYKLENQVVS GTGKFDKSGV
GSSRETKESL DTAFRFFTAN SKSISNTIST KTKDYLMHIS DLQGIGLTNE LAIAELIGLC
SAALDKSVQE STVVIGNMTV GGTIAKVEEF ASVLQVCVDA GAKKVLIPAS SVMDLQTVPP
DLLVKVQPVF YADPTDAVFK ALGVN
//
