ID B1Z6I9_BURA4 Unreviewed; 688 AA.
AC B1Z6I9;
DT 20-MAY-2008, integrated into UniProtKB/TrEMBL.
DT 20-MAY-2008, sequence version 1.
DT 27-MAR-2024, entry version 86.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN OrderedLocusNames=BamMC406_6655 {ECO:0000313|EMBL:ACB69066.1};
OS Burkholderia ambifaria (strain MC40-6).
OG Plasmid pBMC401 {ECO:0000313|EMBL:ACB69066.1,
OG ECO:0000313|Proteomes:UP000001680}.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Burkholderia; Burkholderia cepacia complex.
OX NCBI_TaxID=398577 {ECO:0000313|EMBL:ACB69066.1, ECO:0000313|Proteomes:UP000001680};
RN [1] {ECO:0000313|Proteomes:UP000001680}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MC40-6 {ECO:0000313|Proteomes:UP000001680};
RC PLASMID=Plasmid pBMC401 {ECO:0000313|Proteomes:UP000001680};
RA Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Lang D., Schmutz J.,
RA Larimer F., Land M., Hauser L., Kyrpides N., Lykidis A., Ramette A.,
RA Konstantinidis K., Tiedje J., Richardson P.;
RT "Complete sequence of plasmid 1 of Burkholderia ambifaria MC40-6.";
RL Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; CP001028; ACB69066.1; -; Genomic_DNA.
DR AlphaFoldDB; B1Z6I9; -.
DR KEGG; bac:BamMC406_6655; -.
DR HOGENOM; CLU_000445_104_12_4; -.
DR Proteomes; UP000001680; Plasmid pBMC401.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd16922; HATPase_EvgS-ArcB-TorS-like; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd01007; PBP2_BvgS_HisK_like; 1.
DR CDD; cd17546; REC_hyHK_CKI1_RcsC-like; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 2.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR InterPro; IPR001638; Solute-binding_3/MltF_N.
DR PANTHER; PTHR43047:SF72; OSMOSENSING HISTIDINE PROTEIN KINASE SLN1; 1.
DR PANTHER; PTHR43047; TWO-COMPONENT HISTIDINE PROTEIN KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF00072; Response_reg; 1.
DR Pfam; PF00497; SBP_bac_3; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00062; PBPb; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:ACB69066.1}; Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Plasmid {ECO:0000313|EMBL:ACB69066.1};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transferase {ECO:0000313|EMBL:ACB69066.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 273..292
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 311..533
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 561..680
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT MOD_RES 610
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 688 AA; 74702 MW; 6005DF681C5D6F49 CRC64;
MLLSVSAGTA AATACWKPIF TDEELRWIRD HPVVRIAVEA NWHPIEYVRN GRHAGLVAGY
LSAISKMTGL TFRTVPGTEW GHAYDALSSG KVDLLPGVWR EQVPDRIGDS AVVSAPYLVG
RLTVVTRNNS AMIFGLQRLK GRRIAIKGHG AVEYFIRHSG VPLDVLTFDT EELALASVAA
GEADAALGLD VTILPIVRRQ FTGLLYMSGM LADRPVSLAM LTRAELPLLA SIIDKSLAAI
PVSETAGITR EWIELDDYGK PTIRSIVHYR APVVLAIAMT LMTFAALAWL MWKSRAAAVR
GKRDKAMFLA FVSHEIRTPM QTVLSSLEFL QRSRLPVQQA GRVDAAAAAS ETLLTLLDDI
LDYSRLESRK ITLSAQAVAL DAWARETVDM VRWRAERKAL ALTLDVSAPP SLHVLIDPVR
VRQIALNLLV NAINFTPSGA VMLKVGYVAA RHGRAGTLCL QVRDTGIGIA PDRVSRVFEA
YWQADHAAQQ RMDGCGLGLS ICRELVELIG GSITVDSTPH VETVFTVHLP VTEVEVAPAT
QPLAAPPALT DAAPAHRDAP RLLIVDDHET VRAALLDQCD ALGCIGIVAG GGEDALRYLA
QGRIDMVLLD CNLPDIDGYA LTRMIRQEEA ARKTTRVPII AISAESGDAH KACCLDNGMD
GVLGKPLRHE TLRRAIATWC PAYTEDAR
//
