ID B2FQQ5_STRMK Unreviewed; 334 AA.
AC B2FQQ5;
DT 10-JUN-2008, integrated into UniProtKB/TrEMBL.
DT 10-JUN-2008, sequence version 1.
DT 27-MAR-2024, entry version 75.
DE SubName: Full=Isocitrate/isopropylmalate dehydrogenase {ECO:0000313|EMBL:CAQ44546.1};
GN OrderedLocusNames=Smlt0982 {ECO:0000313|EMBL:CAQ44546.1};
OS Stenotrophomonas maltophilia (strain K279a).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Xanthomonadales;
OC Xanthomonadaceae; Stenotrophomonas; Stenotrophomonas maltophilia group.
OX NCBI_TaxID=522373 {ECO:0000313|EMBL:CAQ44546.1, ECO:0000313|Proteomes:UP000008840};
RN [1] {ECO:0000313|EMBL:CAQ44546.1, ECO:0000313|Proteomes:UP000008840}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K279a {ECO:0000313|EMBL:CAQ44546.1,
RC ECO:0000313|Proteomes:UP000008840};
RX PubMed=18419807; DOI=10.1186/gb-2008-9-4-r74;
RA Crossman L.C., Gould V.C., Dow J.M., Vernikos G.S., Okazaki A.,
RA Sebaihia M., Saunders D., Arrowsmith C., Carver T., Peters N., Adlem E.,
RA Kerhornou A., Lord A., Murphy L., Seeger K., Squares R., Rutter S.,
RA Quail M.A., Rajandream M.A., Harris D., Churcher C., Bentley S.D.,
RA Parkhill J., Thomson N.R., Avison M.B.;
RT "The complete genome, comparative and functional analysis of
RT Stenotrophomonas maltophilia reveals an organism heavily shielded by drug
RT resistance determinants.";
RL Genome Biol. 9:R74.1-R74.13(2008).
CC -!- SIMILARITY: Belongs to the isocitrate and isopropylmalate
CC dehydrogenases family. {ECO:0000256|ARBA:ARBA00007769}.
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DR EMBL; AM743169; CAQ44546.1; -; Genomic_DNA.
DR RefSeq; WP_012479261.1; NC_010943.1.
DR AlphaFoldDB; B2FQQ5; -.
DR EnsemblBacteria; CAQ44546; CAQ44546; Smlt0982.
DR KEGG; sml:Smlt0982; -.
DR eggNOG; COG0473; Bacteria.
DR HOGENOM; CLU_031953_0_1_6; -.
DR Proteomes; UP000008840; Chromosome.
DR GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR Gene3D; 3.40.718.10; Isopropylmalate Dehydrogenase; 1.
DR InterPro; IPR019818; IsoCit/isopropylmalate_DH_CS.
DR InterPro; IPR024084; IsoPropMal-DH-like_dom.
DR PANTHER; PTHR11835; DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE; 1.
DR PANTHER; PTHR11835:SF34; ISOCITRATE DEHYDROGENASE [NAD] SUBUNIT ALPHA, MITOCHONDRIAL; 1.
DR Pfam; PF00180; Iso_dh; 1.
DR SMART; SM01329; Iso_dh; 1.
DR SUPFAM; SSF53659; Isocitrate/Isopropylmalate dehydrogenase-like; 1.
DR PROSITE; PS00470; IDH_IMDH; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000008840}.
FT DOMAIN 4..330
FT /note="Isopropylmalate dehydrogenase-like"
FT /evidence="ECO:0000259|SMART:SM01329"
SQ SEQUENCE 334 AA; 35636 MW; A61ECB99B843926F CRC64;
MTQKITVIRG DGIGPEIMDA TLFVLDQLKT GLEYEDADAG LVALEKHGDL MPAVTLESIA
RNKVALKSPL TTPVGGGFTS INVSLRRHFD LYANVRPAHT FPNTKSRFDN VDLITVRENT
EGAYLAEGQE VSADGETAFS GTRITRKGSE RIVRYAFELA KSTGRKKVTA VHKANIIKST
SGLFLNVARE VAAQYPDIEF QEMIVDNCCM QLVMRPEQFD VIVTTNLFGD IISDLCAGLV
GGLGLAPGAN IGKDAAIFEA VHGTAPDIAG QGKANPCALL LAAAQMLDHI GQPENAERLR
KAIVATMEAK DSLTGDLGGT GTTMSFAKAI ASRL
//
