ID   B2G159_ANOGA            Unreviewed;       256 AA.
AC   B2G159;
DT   10-JUN-2008, integrated into UniProtKB/TrEMBL.
DT   10-JUN-2008, sequence version 1.
DT   24-JAN-2024, entry version 42.
DE   RecName: Full=Origin recognition complex subunit 4 {ECO:0000256|ARBA:ARBA00019083};
DE   Flags: Fragment;
GN   Name=ENSANGG00000005748 {ECO:0000313|EMBL:CAO85248.1};
OS   Anopheles gambiae (African malaria mosquito).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Anophelinae; Anopheles.
OX   NCBI_TaxID=7165 {ECO:0000313|EMBL:CAO85248.1};
RN   [1] {ECO:0000313|EMBL:CAO85248.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=M4 {ECO:0000313|EMBL:CAO85248.1};
RA   Cohuet A., Krishnakumar S., Simard F., Morlais I., Koutsos A.,
RA   Fontenille D., Mindrinos M., Kafatos F.C.;
RT   "Genetic diversity and adaptive evolution in Anopheles gambiae innate
RT   immune system.";
RL   Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the ORC4 family.
CC       {ECO:0000256|ARBA:ARBA00005334}.
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DR   EMBL; AM776790; CAO85248.1; -; Genomic_DNA.
DR   VEuPathDB; VectorBase:AGAP007063; -.
DR   HOGENOM; CLU_007115_0_1_1; -.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0000808; C:origin recognition complex; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR016527; ORC4.
DR   InterPro; IPR032705; ORC4_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR12087; ORIGIN RECOGNITION COMPLEX SUBUNIT 4; 1.
DR   PANTHER; PTHR12087:SF0; ORIGIN RECOGNITION COMPLEX SUBUNIT 4; 1.
DR   Pfam; PF14629; ORC4_C; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   3: Inferred from homology;
KW   DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242}.
FT   DOMAIN          105..256
FT                   /note="Origin recognition complex subunit 4 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF14629"
FT   UNSURE          167
FT                   /note="I or L"
FT                   /evidence="ECO:0000313|EMBL:CAO85248.1"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:CAO85248.1"
FT   NON_TER         256
FT                   /evidence="ECO:0000313|EMBL:CAO85248.1"
SQ   SEQUENCE   256 AA;  29627 MW;  14DDBF9A7B6C5D5E CRC64;
     KVFGSFAENL AFLLECLKAG DRKKSKSVIF LLEEFDLFCS HHNQTLLYNL FDVAQSAQAP
     ICVLGLTARL DVIELLEKRV KSRFSHRQIF LLPREBGFEE RLELFGXLLK LPTEQEVRTF
     AXTHPTIPPD VLNNDELALL RNLFNPRQYX LPSKWVTQWN RTIDKLXKSA EVQTVLQNMY
     EYDVLEGPFR MQLFELVNGL DDEHPAITIE SIQQLGERYE SDDKVKLLAG SSVLEICLVI
     AIKHHSEIYD RDPFNF
//