ID B2GSW9_DANRE Unreviewed; 863 AA.
AC B2GSW9;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=Chaf1a protein {ECO:0000313|EMBL:AAI65675.1};
GN Name=chaf1a {ECO:0000313|EMBL:AAI65675.1,
GN ECO:0000313|ZFIN:ZDB-GENE-030131-5366};
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danio.
OX NCBI_TaxID=7955 {ECO:0000313|EMBL:AAI65675.1};
RN [1] {ECO:0000313|EMBL:AAI65675.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=PCR rescue {ECO:0000313|EMBL:AAI65675.1};
RG NIH - Zebrafish Gene Collection (ZGC) project;
RL Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the CHAF1A family.
CC {ECO:0000256|ARBA:ARBA00006913}.
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DR EMBL; BC165675; AAI65675.1; -; mRNA.
DR RefSeq; NP_001038478.2; NM_001045013.2.
DR AlphaFoldDB; B2GSW9; -.
DR SMR; B2GSW9; -.
DR Ensembl; ENSDART00000111711; ENSDARP00000101598; ENSDARG00000062152.
DR GeneID; 563212; -.
DR KEGG; dre:563212; -.
DR AGR; ZFIN:ZDB-GENE-030131-5366; -.
DR CTD; 10036; -.
DR ZFIN; ZDB-GENE-030131-5366; chaf1a.
DR OMA; DPWAQDK; -.
DR OrthoDB; 10904at2759; -.
DR PhylomeDB; B2GSW9; -.
DR ExpressionAtlas; B2GSW9; baseline and differential.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR InterPro; IPR029105; CAF1-p150_C2.
DR InterPro; IPR029091; CAF1_p150_N.
DR InterPro; IPR022043; CAF1A.
DR PANTHER; PTHR15272:SF0; CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT A; 1.
DR PANTHER; PTHR15272; CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT A CAF-1 SUBUNIT A; 1.
DR Pfam; PF11600; CAF-1_p150; 1.
DR Pfam; PF15539; CAF1-p150_C2; 1.
DR Pfam; PF15557; CAF1-p150_N; 1.
DR Pfam; PF12253; CAF1A; 1.
PE 2: Evidence at transcript level;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Chaperone {ECO:0000256|ARBA:ARBA00023186};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242}.
FT DOMAIN 17..150
FT /note="Chromatin assembly factor 1 subunit p150 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF15557"
FT DOMAIN 581..852
FT /note="Chromatin assembly factor 1 subunit p150 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF15539"
FT REGION 1..353
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 423..466
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 513..579
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 749..863
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 41..55
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 112..126
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 137..153
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 177..196
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 200..243
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 248..353
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 513..547
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 749..785
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 802..817
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 820..847
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 863 AA; 97223 MW; 61C1251E909E9E9F CRC64;
MVVVMLAAEE PLASTPRRDM DCVGKANTNK KLVQARLPFK RLNPEPKECN EPKRTKGPVA
PKCSEPSDQE NDQDSSSISH HGPALVNGRG PLDCFMSRRK RSPLRSAPEA TIDLTEDSND
SAKQQPAPPI AATCPLSEEK TKTSEGTTEP TIPLTEEETE KDEAEDVDAL PLLDITQDSD
TEEEEEEEEE EEEQQQEAEV SHGNESVLST GSTSSASVIA SSPEPSKSAP TTPASTSRIN
AANKVKRRSL KSVQEQEEKQ RQRDEKERLK QEAKAAKEKK KEEARKMKEE KEREKKEKKE
KDEKERREKK ERDEKEKADK LKAKEEQRQM KIEAKLEEKR KKEEEKRLKE EKDRIKAEKA
EITRFLQKPK TQLAPKTLAS ACGKFAPFEI KAHMSLAPLT RVQCEDSVLE DLDRYLAQPD
STLNGLKDWT GHKPRSSGPT RPRHSAQGDC VVITESQKAD DGPDRSRYGR MKLLHFHDNY
RPAYWGTWSK KSTHISPRCP LRLDKDLLDY EVDSDEEWEE EEPGESLSHS EGDDDDEAGE
DDDDDDGFFV PHGYLSEGEG ALEDEEGGDP EKQKVRQRMK AREWENELMS KGKVKVLEAV
VRGCFWEGEK PLPDFLQPYA VCMLEPLSKD EASTPEQDAS RQQRNEKLLT MLLPLLHGNV
NSNKVIITEF LEFCRQQTSS PTESLLNTTE SIPPRIHVRR IIKENAVYEK RSTFKRCCWY
VHADVLARYS QEALPVPCQW SYLTSGANVT RDEHSGSQGN SPTTNSSTTP SNKRKSASSH
SITKYMKKCG ESEQTEAMET DGFQADTEDD EDDDCIIIGE QSGSSEQDIN TSLPQTDRET
EPMDTSASET AALALPCPTP ATA
//
