ID B2GT29_DANRE Unreviewed; 462 AA.
AC B2GT29;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE RecName: Full=Cytokine-like nuclear factor N-PAC {ECO:0000256|ARBA:ARBA00034140};
DE AltName: Full=Glyoxylate reductase 1 homolog {ECO:0000256|ARBA:ARBA00030287};
DE AltName: Full=Nuclear protein NP60 {ECO:0000256|ARBA:ARBA00032038};
DE AltName: Full=Putative oxidoreductase GLYR1 {ECO:0000256|ARBA:ARBA00034145};
GN Name=zgc:103629 {ECO:0000313|EMBL:AAI65738.1};
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danio.
OX NCBI_TaxID=7955 {ECO:0000313|EMBL:AAI65738.1};
RN [1] {ECO:0000313|EMBL:AAI65738.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=PCR rescue {ECO:0000313|EMBL:AAI65738.1};
RG NIH - Zebrafish Gene Collection (ZGC) project;
RL Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Chromosome {ECO:0000256|ARBA:ARBA00004286}.
CC -!- SIMILARITY: Belongs to the HIBADH-related family. NP60 subfamily.
CC {ECO:0000256|ARBA:ARBA00007598}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; BC165738; AAI65738.1; -; mRNA.
DR RefSeq; NP_001007772.1; NM_001007771.1.
DR AlphaFoldDB; B2GT29; -.
DR SMR; B2GT29; -.
DR GeneID; 493611; -.
DR KEGG; dre:493611; -.
DR AGR; ZFIN:ZDB-GENE-041121-5; -.
DR CTD; 84656; -.
DR ZFIN; ZDB-GENE-041121-5; glyr1.
DR OrthoDB; 103196at2759; -.
DR PhylomeDB; B2GT29; -.
DR GO; GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR CDD; cd05836; PWWP_GLYR1; 1.
DR Gene3D; 2.30.30.140; -; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR006115; 6PGDH_NADP-bd.
DR InterPro; IPR035501; GLYR1_PWWP.
DR InterPro; IPR029154; HIBADH-like_NADP-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR000313; PWWP_dom.
DR PANTHER; PTHR43580; OXIDOREDUCTASE GLYR1-RELATED; 1.
DR PANTHER; PTHR43580:SF2; OXIDOREDUCTASE GLYR1-RELATED; 1.
DR Pfam; PF14833; NAD_binding_11; 1.
DR Pfam; PF03446; NAD_binding_2; 1.
DR Pfam; PF00855; PWWP; 1.
DR SMART; SM00293; PWWP; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 1.
DR PROSITE; PS50812; PWWP; 1.
PE 2: Evidence at transcript level;
KW Chromosome {ECO:0000256|ARBA:ARBA00022454}.
FT DOMAIN 8..66
FT /note="PWWP"
FT /evidence="ECO:0000259|PROSITE:PS50812"
FT REGION 91..139
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 91..131
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 462 AA; 50601 MW; 8B5A17C1E9D270E6 CRC64;
MATVHLRIGD LVWGKLGRYP PWPGKVVSPP KDLKKPRGKK CFFVKFFGTE DHAWIKVEQL
KPYHPHKEEM IKVNKGKRFQ QAVDAVEEYL KKAKGKDQSH SDDKSKSDKG RKAAKPMKII
EEDDEDAFKG GSSDKPASSM EPITKRLKII EEDTRSTSIQ AADSTAINGS ITPTDKRIGF
LGLGLMGSGV VSNLLKMGHV VTVWNRTAEK CDLFIQEGAR LGRTPAEVVS MCDITFSCVS
DPKAARDLVL GPSGVLQGIR PGKCYVEMST VDPETITELS QVITSRGGRF LEAPVSGSQQ
LSNDGMLVIV AAGDRSVYED CSSCFQAMGK TSFFIAGEAG NAARMMLILN MVQGSFMATI
AEGLTLAQAT GQSQQTFLDI LCQGQMASTF VDQKCQNILQ GNFKPDYYLK HIQKDLRLAI
SMGDSVNHPT PMAAAANEVY KRAKALDQSD NDMSAVYRAY IH
//
