ID B2HK94_MYCMM Unreviewed; 742 AA.
AC B2HK94;
DT 10-JUN-2008, integrated into UniProtKB/TrEMBL.
DT 10-JUN-2008, sequence version 1.
DT 27-MAR-2024, entry version 87.
DE SubName: Full=Sensor-component of a two-component regulator {ECO:0000313|EMBL:ACC43591.1};
GN OrderedLocusNames=MMAR_5186 {ECO:0000313|EMBL:ACC43591.1};
OS Mycobacterium marinum (strain ATCC BAA-535 / M).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium ulcerans group.
OX NCBI_TaxID=216594 {ECO:0000313|EMBL:ACC43591.1, ECO:0000313|Proteomes:UP000001190};
RN [1] {ECO:0000313|EMBL:ACC43591.1, ECO:0000313|Proteomes:UP000001190}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-535 / M {ECO:0000313|Proteomes:UP000001190};
RX PubMed=18403782; DOI=10.1101/gr.075069.107;
RA Stinear T.P., Seemann T., Harrison P.F., Jenkin G.A., Davies J.K.,
RA Johnson P.D., Abdellah Z., Arrowsmith C., Chillingworth T., Churcher C.,
RA Clarke K., Cronin A., Davis P., Goodhead I., Holroyd N., Jagels K.,
RA Lord A., Moule S., Mungall K., Norbertczak H., Quail M.A.,
RA Rabbinowitsch E., Walker D., White B., Whitehead S., Small P.L., Brosch R.,
RA Ramakrishnan L., Fischbach M.A., Parkhill J., Cole S.T.;
RT "Insights from the complete genome sequence of Mycobacterium marinum on the
RT evolution of Mycobacterium tuberculosis.";
RL Genome Res. 18:729-741(2008).
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DR EMBL; CP000854; ACC43591.1; -; Genomic_DNA.
DR RefSeq; WP_012396700.1; NC_010612.1.
DR AlphaFoldDB; B2HK94; -.
DR STRING; 216594.MMAR_5186; -.
DR KEGG; mmi:MMAR_5186; -.
DR eggNOG; COG2172; Bacteria.
DR eggNOG; COG2202; Bacteria.
DR eggNOG; COG2208; Bacteria.
DR HOGENOM; CLU_000445_43_2_11; -.
DR OrthoDB; 163538at2; -.
DR Proteomes; UP000001190; Chromosome.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd16936; HATPase_RsbW-like; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 1.10.1240.30; KaiA/RbsU domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR017944; KaiA/RbsU_helical_domain_sf.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR036457; PPM-type-like_dom_sf.
DR InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR InterPro; IPR014787; PSer_Pase_RsbU_N.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR43156:SF2; MULTIDOMAIN REGULATORY PROTEIN RV1364C; 1.
DR PANTHER; PTHR43156; STAGE II SPORULATION PROTEIN E-RELATED; 1.
DR Pfam; PF13581; HATPase_c_2; 1.
DR Pfam; PF00989; PAS; 1.
DR Pfam; PF08673; RsbU_N; 1.
DR Pfam; PF07228; SpoIIE; 1.
DR SMART; SM00086; PAC; 1.
DR SMART; SM00091; PAS; 1.
DR SMART; SM00331; PP2C_SIG; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF101215; KaiA/RbsU domain; 1.
DR SUPFAM; SSF81606; PP2C-like; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001190}.
FT DOMAIN 113..155
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 183..235
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
SQ SEQUENCE 742 AA; 80308 MW; 3E38BF38208EF075 CRC64;
MTETGDFGAV DAFQTQYADA LRAYLDTRDE NSLAVGHEFG RRALQEQISI LDIIENHFRL
LDEISPNPGS DRSVALEFLL QTLAALDVAT RGFLDGTKRY EEQRARAEDL AHRDKFRSAL
VNSLQEGFFV ADDEGAVIDM NSAFAEILGY PPEGLPYRWP HPWLVDRKSA AQQQERVRHE
GSADYETPVR HQDGHLSWVA VSINAVRGSG SDRDVYVGTV RDITAERAFA ARESAVLRLA
TSVSVAKSVS EVLSITLEEC RTAVDVQRVV AVMWPPSDGE PTVQVAGEPA ESSWRALDPQ
LRETFLGARA QLPLTARPIE WPDSPGRAQG LVAVLSGTAD VALWLELGAP RWVTAEDRLL
VTVLVGHLSL AIGHVRQFES ARETSLTLQR AMLPPVKPPP GFAVRYEPAV PPLEIGGDWY
DVLPIGEHRI GIVVGDCVGR GLPAAAIMGQ LRSSARALLL TGAQPALLLE QLDAAASLIP
DAYCTTVFLA ILDTESGILD YSNAGHMPAV LAEPKSGPVL LTDARSVPLA VRRVEPRPEA
TQVLPPGSTL LLFTDGLVER RYESIDEGLG RVADVVADSV MLPIDAVADA VLSQLAPTGG
YDDDVAMVAY RYQHGPLRIE TSATPDQLVI VRRQLLSWLQ AAEVPDEQAG DIVLVVSEAC
TNCIEHAYRG QSVGTMLLDV EAADWAIHAR VVDSGSWKKP AADPGNGGRG MTLIRAISDE
VEIDNSPGGT AIDMTFRLPS ED
//
