ID B2HRA2_MYCMM Unreviewed; 583 AA.
AC B2HRA2;
DT 10-JUN-2008, integrated into UniProtKB/TrEMBL.
DT 10-JUN-2008, sequence version 1.
DT 27-MAR-2024, entry version 73.
DE SubName: Full=Conserved hypothetical transport protein {ECO:0000313|EMBL:ACC42533.1};
GN OrderedLocusNames=MMAR_4126 {ECO:0000313|EMBL:ACC42533.1};
OS Mycobacterium marinum (strain ATCC BAA-535 / M).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium ulcerans group.
OX NCBI_TaxID=216594 {ECO:0000313|EMBL:ACC42533.1, ECO:0000313|Proteomes:UP000001190};
RN [1] {ECO:0000313|EMBL:ACC42533.1, ECO:0000313|Proteomes:UP000001190}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-535 / M {ECO:0000313|Proteomes:UP000001190};
RX PubMed=18403782; DOI=10.1101/gr.075069.107;
RA Stinear T.P., Seemann T., Harrison P.F., Jenkin G.A., Davies J.K.,
RA Johnson P.D., Abdellah Z., Arrowsmith C., Chillingworth T., Churcher C.,
RA Clarke K., Cronin A., Davis P., Goodhead I., Holroyd N., Jagels K.,
RA Lord A., Moule S., Mungall K., Norbertczak H., Quail M.A.,
RA Rabbinowitsch E., Walker D., White B., Whitehead S., Small P.L., Brosch R.,
RA Ramakrishnan L., Fischbach M.A., Parkhill J., Cole S.T.;
RT "Insights from the complete genome sequence of Mycobacterium marinum on the
RT evolution of Mycobacterium tuberculosis.";
RL Genome Res. 18:729-741(2008).
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DR EMBL; CP000854; ACC42533.1; -; Genomic_DNA.
DR AlphaFoldDB; B2HRA2; -.
DR STRING; 216594.MMAR_4126; -.
DR KEGG; mmi:MMAR_4126; -.
DR eggNOG; COG1226; Bacteria.
DR HOGENOM; CLU_477196_0_0_11; -.
DR Proteomes; UP000001190; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR Gene3D; 3.30.70.1450; Regulator of K+ conductance, C-terminal domain; 1.
DR InterPro; IPR013099; K_chnl_dom.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR006037; RCK_C.
DR InterPro; IPR036721; RCK_C_sf.
DR InterPro; IPR003148; RCK_N.
DR PANTHER; PTHR43833:SF11; POTASSIUM CHANNEL; 1.
DR PANTHER; PTHR43833; POTASSIUM CHANNEL PROTEIN 2-RELATED-RELATED; 1.
DR Pfam; PF07885; Ion_trans_2; 1.
DR Pfam; PF02080; TrkA_C; 1.
DR Pfam; PF02254; TrkA_N; 2.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 2.
DR SUPFAM; SSF116726; TrkA C-terminal domain-like; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
DR PROSITE; PS51202; RCK_C; 1.
DR PROSITE; PS51201; RCK_N; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001190};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 227..249
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 287..312
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 332..353
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 331..424
FT /note="RCK N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51201"
FT DOMAIN 475..557
FT /note="RCK C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51202"
FT REGION 551..583
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 583 AA; 63220 MW; F394F871080D21CA CRC64;
MSMRRHIIVS GDDALANTIV EELNSAGVTI LKLASDELND AQLAQAIAVI CAGDDDARNL
EIALLARRAD PHVRVVARLA NDVLREAMAA DNGPGAILDV ADLAAPSVVE ACLARTVHPF
EAAGIEFVVW RAEAPRDATL REIYGDLAPV AVVRGKNSPT PGEVLTCPGR DLRVHAGDET
AMVGTAEDLA ARGIKVPRPT STRFRLLRLR QISDAARALR NDVNPMFFKA LAAMATLLAV
STTLLRFAYR HPPGMTWLDA LYFSTETIAT VGYGDFSFSH QHPWLRVFSI TLMFAGVTTT
AILVAFIADL LLSRRFTRSA GRRRVRQLRN HVIVVGLGSF GIRVVRDLIA AGYDVAVIEL
DENSRFLESA AELDVPVIFG DATLPQTLES ACIAHARAMA VLTQDDMVNI ETGIVLREML
GAVKANRRDI PLVLRVYDRE LGGAVAQRFD FESVRSTVEL AAPWFIGAAM GLQVLGTFSV
GQSSFMVGGM HVSAQSELDG LSMRELVTGT RVIAITRPDE PPQLHPRRDT RLRAGDTAYL
VGPYRELLAT LRKGQPPQQP ASGDGHWPEV ATVDNVGPLD RPN
//
