ID   B2ISC6_STRPS            Unreviewed;       696 AA.
AC   B2ISC6;
DT   10-JUN-2008, integrated into UniProtKB/TrEMBL.
DT   10-JUN-2008, sequence version 1.
DT   27-MAR-2024, entry version 61.
DE   SubName: Full=Glycosyl transferase, family 2/glycosyl transferase family 8 {ECO:0000313|EMBL:ACB91001.1};
GN   OrderedLocusNames=SPCG_1749 {ECO:0000313|EMBL:ACB91001.1};
OS   Streptococcus pneumoniae (strain CGSP14).
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=516950 {ECO:0000313|EMBL:ACB91001.1, ECO:0000313|Proteomes:UP000001682};
RN   [1] {ECO:0000313|EMBL:ACB91001.1, ECO:0000313|Proteomes:UP000001682}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CGSP14 {ECO:0000313|EMBL:ACB91001.1,
RC   ECO:0000313|Proteomes:UP000001682};
RX   PubMed=19361343; DOI=10.1186/1471-2164-10-158;
RA   Ding F., Tang P., Hsu M.-H., Cui P., Hu S., Yu J., Chiu C.-H.;
RT   "Genome evolution driven by host adaptations results in a more virulent and
RT   antimicrobial-resistant Streptococcus pneumoniae serotype 14.";
RL   BMC Genomics 10:158-158(2009).
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DR   EMBL; CP001033; ACB91001.1; -; Genomic_DNA.
DR   AlphaFoldDB; B2ISC6; -.
DR   CAZy; GT2; Glycosyltransferase Family 2.
DR   CAZy; GT8; Glycosyltransferase Family 8.
DR   KEGG; spw:SPCG_1749; -.
DR   HOGENOM; CLU_034940_0_0_9; -.
DR   Proteomes; UP000001682; Chromosome.
DR   GO; GO:0016757; F:glycosyltransferase activity; IEA:InterPro.
DR   CDD; cd00761; Glyco_tranf_GTA_type; 1.
DR   CDD; cd04194; GT8_A4GalT_like; 1.
DR   InterPro; IPR001173; Glyco_trans_2-like.
DR   InterPro; IPR002495; Glyco_trans_8.
DR   InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR   PANTHER; PTHR22916; GLYCOSYLTRANSFERASE; 1.
DR   PANTHER; PTHR22916:SF3; UDP-GLCNAC:BETAGAL BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE-LIKE PROTEIN 1; 1.
DR   Pfam; PF01501; Glyco_transf_8; 1.
DR   Pfam; PF00535; Glycos_transf_2; 1.
DR   SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 2.
PE   4: Predicted;
KW   Manganese {ECO:0000256|ARBA:ARBA00023211};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:ACB91001.1}.
FT   DOMAIN          8..136
FT                   /note="Glycosyltransferase 2-like"
FT                   /evidence="ECO:0000259|Pfam:PF00535"
SQ   SEQUENCE   696 AA;  81538 MW;  4837DB5355C46040 CRC64;
     MLVDDKITVI VPVYNVENYL RKCLDSIITQ TYKNIEIVVV NDGSTDASGE ICKEFSEMDH
     RILYIEQENA GLSAARNTGL NNMSGNYVTF VDSDDWIELD YVETLYKEIT EYQADIAVGN
     YYSFNESEGM FYFHISGDSY YEKVYDNVSI FENLYETQEM RSFALISAWG KLYKARLFEQ
     LRFDMGKLGE DGYLNQKVYL LSEKVIYLNK SLYAYRIRKG SLSRIWTEKW MHALVDAMSE
     RITLLANMGY PLEKHLAIYR QMLEFSLSNG QASGLSDTAT YKEFEMKQRL LNQLSRQEES
     EKKAIVLAAN YAYVDQVLTT IKSICYHNRS IRFYLIHSDF PNEWIKQLNK RLEKFDSEII
     NCRVTSEQIS CYKSDISYTV FLRYFIADFV QEDKALYLDC DLVVTKNLDD LFATDLQDYR
     LAAVRDFGGR AYFGQEIFNA GVLLVNNAFW KKENMIQKLI DVTNEWHDKV DQADQSILNM
     LFEHKWLELD FDYNHIVIHK QFADYQLPEG QDYPAIIHYL SHRKPWKDLA AQTYREVWWY
     YHGLEWTELG QNHHLHPLQR SHIYPIKEPF TCLIYTASDH IEQIETLVQS LPDIQFKIAA
     RVIVSDRLAQ MTIYPNVTIF NGIHYLVDVD NELVETSQVL LDINHGEKTE EIINQFARLG
     KTILSFENTK TYEAGQEAYA VDQVQAMIEK LREISK
//