ID B2JAQ0_NOSP7 Unreviewed; 708 AA.
AC B2JAQ0;
DT 10-JUN-2008, integrated into UniProtKB/TrEMBL.
DT 10-JUN-2008, sequence version 1.
DT 27-MAR-2024, entry version 98.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN OrderedLocusNames=Npun_AR133 {ECO:0000313|EMBL:ACC85004.1};
OS Nostoc punctiforme (strain ATCC 29133 / PCC 73102).
OG Plasmid pNPUN01 {ECO:0000313|EMBL:ACC85004.1,
OG ECO:0000313|Proteomes:UP000001191}.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Nostocaceae; Nostoc.
OX NCBI_TaxID=63737 {ECO:0000313|EMBL:ACC85004.1, ECO:0000313|Proteomes:UP000001191};
RN [1] {ECO:0000313|Proteomes:UP000001191}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29133 / PCC 73102 {ECO:0000313|Proteomes:UP000001191};
RC PLASMID=Plasmid pNPUN01 {ECO:0000313|Proteomes:UP000001191};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J.,
RA Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Meeks J.C., Elhai J.,
RA Campbell E.L., Thiel T., Longmire J., Potts M., Atlas R.;
RT "Complete sequence of plasmid 1 of Nostoc punctiforme ATCC 29133.";
RL Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; CP001038; ACC85004.1; -; Genomic_DNA.
DR RefSeq; WP_012413022.1; NC_010631.1.
DR AlphaFoldDB; B2JAQ0; -.
DR EnsemblBacteria; ACC85004; ACC85004; Npun_AR133.
DR KEGG; npu:Npun_AR133; -.
DR HOGENOM; CLU_000445_114_39_3; -.
DR OrthoDB; 500279at2; -.
DR PhylomeDB; B2JAQ0; -.
DR Proteomes; UP000001191; Plasmid pNPUN01.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 3.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 3.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR013655; PAS_fold_3.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR NCBIfam; TIGR00229; sensory_box; 3.
DR PANTHER; PTHR43065:SF10; PEROXIDE STRESS-ACTIVATED HISTIDINE KINASE MAK3; 1.
DR PANTHER; PTHR43065; SENSOR HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00989; PAS; 1.
DR Pfam; PF08447; PAS_3; 1.
DR Pfam; PF08448; PAS_4; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00086; PAC; 3.
DR SMART; SM00091; PAS; 3.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 3.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50113; PAC; 3.
DR PROSITE; PS50112; PAS; 2.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:ACC85004.1};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Plasmid {ECO:0000313|EMBL:ACC85004.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001191};
KW Transferase {ECO:0000313|EMBL:ACC85004.1}.
FT DOMAIN 85..137
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 138..208
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 211..263
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 264..329
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 333..385
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 419..677
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 708 AA; 79938 MW; 53301175422BFBA8 CRC64;
MSQNYFFNSD LQRDDLYCSF LENLPIAAAI LDCEMKYLLT SQGWLSELGL EGQDIIGRSH
LEVFRQFCEP LTQAYQYCLM AAVELCVEEQ FQQVDGLTGW RQWTLRPWCS STRVVNGVML
VAEDVTDRKQ AELALRHSEE RYRFLITAIS QIIWDTKAEG EFINEQPGWS AFTGQTFEEL
KGWGWLNAVH PDDRLHTAKV WSQAVASRTL YKLEHRLRRH DGEYCHMSVR AFPILNPDGG
IREWIGVHTD ITEYKQAQEA MLCLAAIVES SDDAIISKTL DGVIVSWNRG AEALFGYQAQ
EVIGQPMAML VPGDRINEEP QILKKLRQGE RVDHFETVRQ RKDGTLIDLS LTISPVKDST
GKIIGASKIA RDISARKDAQ EALRQKAADL ETTLLELKRT QTQLVQNEKM SSLGQLVAGV
AHEINNPVNF IYANFKPANE YIQHLLGLLQ LYQQHYPSPA PEIQGKSEEI DLEFLLEDLP
KLLCSMEVGA DRIKKIVLSL RNFSRMDEAE MKAVNIHEGI DSTLMILQNR LKAKHDHPGI
EIIKEYGNLP LVECYAGQLN QVFMNIISNA IDALEEPHQS CTLQEIEQKT SEIRIFTAMV
GSDHVQIRIV DNGPGIPEFV QKRLCDPFFT TKPVGKGTGL GMSISYQIVT EKHGGSLRYH
SIPGQGAEFV IEIPIRQSKC TLPMLGDKTA NKTISETTLM VLSDFGDQ
//
