ID   B2KII5_RHIFE            Unreviewed;       529 AA.
AC   B2KII5;
DT   10-JUN-2008, integrated into UniProtKB/TrEMBL.
DT   10-JUN-2008, sequence version 1.
DT   24-JAN-2024, entry version 38.
DE   SubName: Full=Rho GTPase activating protein 4 (Predicted) {ECO:0000313|EMBL:ACC68893.1};
GN   Name=ARHGAP4 {ECO:0000313|EMBL:ACC68893.1};
OS   Rhinolophus ferrumequinum (Greater horseshoe bat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; Rhinolophidae;
OC   Rhinolophinae; Rhinolophus.
OX   NCBI_TaxID=59479 {ECO:0000313|EMBL:ACC68893.1};
RN   [1] {ECO:0000313|EMBL:ACC68893.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Antonellis A., Benjamin B., Blakesley R.W., Bouffard G.G., Brinkley C.,
RA   Brooks S., Chu G., Chub I., Coleman H., Fuksenko T., Gestole M.,
RA   Gregory M., Guan X., Gupta J., Gurson N., Han E., Han J., Hansen N.,
RA   Hargrove A., Hines-Harris K., Ho S.-L., Hu P., Hunter G., Hurle B.,
RA   Idol J.R., Johnson T., Knight E., Kwong P., Lee-Lin S.-Q., Legaspi R.,
RA   Madden M., Maduro Q.L., Maduro V.B., Margulies E.H., Masiello C.,
RA   Maskeri B., McDowell J., Merkulov G., Montemayor C., Mullikin J.C.,
RA   Park M., Prasad A., Ramsahoye C., Reddix-Dugue N., Riebow N., Schandler K.,
RA   Schueler M.G., Sison C., Smith L., Stantripop S., Thomas J.W., Thomas P.J.,
RA   Tsipouri V., Young A., Green E.D.;
RT   "NISC Comparative Sequencing Initiative.";
RL   Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; DP000725; ACC68893.1; -; Genomic_DNA.
DR   AlphaFoldDB; B2KII5; -.
DR   CDD; cd07656; F-BAR_srGAP; 1.
DR   Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR   InterPro; IPR027267; AH/BAR_dom_sf.
DR   InterPro; IPR031160; F_BAR.
DR   InterPro; IPR001060; FCH_dom.
DR   PANTHER; PTHR14166:SF16; RHO GTPASE-ACTIVATING PROTEIN 4; 1.
DR   PANTHER; PTHR14166; SLIT-ROBO RHO GTPASE ACTIVATING PROTEIN; 1.
DR   Pfam; PF00611; FCH; 1.
DR   SMART; SM00055; FCH; 1.
DR   SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR   PROSITE; PS51741; F_BAR; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|PROSITE-ProRule:PRU01077}.
FT   DOMAIN          19..328
FT                   /note="F-BAR"
FT                   /evidence="ECO:0000259|PROSITE:PS51741"
FT   REGION          182..232
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          419..445
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        182..198
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        207..224
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        419..434
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   529 AA;  59407 MW;  9969F83A49D28E3A CRC64;
     MAAHGKLRRE RGLQAEYETQ VKEMRWQLSE QLRCLELQGE LRRELLQELA EFMRRRADVE
     LEYSRGLDKL AERFSSRGGR LGGSSREHQS FRKEPSLLSS LHCWAVLLQQ TRQQSRESAA
     LSEVLAGPLA QRLSHIAEDV GRIVKKSKDL EQQLQEELLE VVSELQTVKK TYQVYHTESM
     SAEAKLREAE RQEEKRTGRS AAAAATATAA ATATATSTTE AGPLRKTSLK KGSRLVQKRQ
     AKFLEHKLKC TKARNEYLLS LASVNAAVSN YYLHDVLDLM DCCDTGFHLA LGQVLRSYTA
     AESRTQASQM QGLGSLEEAV EALDPPGDKA KVLEVHAVAF CPPLRFDYQP HEGDEVSDIR
     VEVELRDEIL PRAQNIQSRL DRQTIETEEV NKTLKATLQA LLEVVALEDG DMLDSFQACP
     STESLKSTSS DPGARQAGRR RGQQQETETF YIMKLQEYLS GRSVLAKLQA KHEKLQEAIQ
     RGGPHSCPPC SLPLHPQSQE QYLPSALLPG NPTWLMLLSA QRHWLACRK
//