ID B2TKD3_CLOBB Unreviewed; 486 AA.
AC B2TKD3; U4PJT6;
DT 01-JUL-2008, integrated into UniProtKB/TrEMBL.
DT 01-JUL-2008, sequence version 1.
DT 27-MAR-2024, entry version 95.
DE SubName: Full=GntR-family transcriptional regulator {ECO:0000313|EMBL:ACD22261.1};
GN OrderedLocusNames=CLL_A1574 {ECO:0000313|EMBL:ACD22261.1};
OS Clostridium botulinum (strain Eklund 17B / Type B).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=935198 {ECO:0000313|EMBL:ACD22261.1, ECO:0000313|Proteomes:UP000001195};
RN [1] {ECO:0000313|Proteomes:UP000001195}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Eklund 17B / Type B {ECO:0000313|Proteomes:UP000001195};
RA Brinkac L.M., Brown J.L., Bruce D., Detter C., Munk C., Smith L.A.,
RA Smith T.J., Sutton G., Brettin T.S.;
RT "Complete sequence of Clostridium botulinum strain Eklund.";
RL Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: In the C-terminal section; belongs to the class-I
CC pyridoxal-phosphate-dependent aminotransferase family.
CC {ECO:0000256|ARBA:ARBA00005384}.
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DR EMBL; CP001056; ACD22261.1; -; Genomic_DNA.
DR AlphaFoldDB; B2TKD3; -.
DR KEGG; cbk:CLL_A1574; -.
DR PATRIC; fig|935198.13.peg.1520; -.
DR HOGENOM; CLU_017584_0_0_9; -.
DR Proteomes; UP000001195; Chromosome.
DR GO; GO:0003824; F:catalytic activity; IEA:UniProt.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR CDD; cd00609; AAT_like; 1.
DR CDD; cd07377; WHTH_GntR; 1.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR004839; Aminotransferase_I/II.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR InterPro; IPR000524; Tscrpt_reg_HTH_GntR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR42790; AMINOTRANSFERASE; 1.
DR PANTHER; PTHR42790:SF8; GNTR-FAMILY TRANSCRIPTIONAL REGULATOR; 1.
DR Pfam; PF00155; Aminotran_1_2; 1.
DR Pfam; PF00392; GntR; 1.
DR PRINTS; PR00035; HTHGNTR.
DR SMART; SM00345; HTH_GNTR; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50949; HTH_GNTR; 1.
PE 3: Inferred from homology;
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 12..80
FT /note="HTH gntR-type"
FT /evidence="ECO:0000259|PROSITE:PS50949"
SQ SEQUENCE 486 AA; 55700 MW; A703FB7B5ED299BD CRC64;
MIFSTLNINK NKPIYLQIKQ HIINGIKKGE LKRDSKLPST REVSKFLNIS RNSVISAYEE
LESNGIIVTK RGIGTFIAIE SETKCYSYNI DYSSMTNDYS NNLRNLDIIK DEFPYKKGLI
SFKSIAPESN LFNLDDFKRA LLDAWSYENT NLLNYGYAKG YKPLIDYFFD YMIKKRVNVD
SKDILITNGF TEAFDIVMSS LTTKGDTIIC EKPTHNTAIK IMKSYGLNVV QINMDKDGLD
LIELEKGLSE CKPKFGYLIP SYNNPTGIVT KSERRKEIYN LFRKYSVPII EDGFNEELLY
SSSPIDPIAS LAGEGNGIIY IGSLSKILFP GLRIGWIFAD QKLIDILESV KRGKTIHSSF
LDQSAFYYYL KSGSFNKYLK NVRKYYKDKY NLVIETINNH IPYEYITGEG GLHIFIKLKD
HINSRQLLEL CYKDGVIFMP GDIFYEGNAD ETTFRIGFGR VTDNDIRIGI KIIGDNIKFL
SRKSKI
//
