ID B2UPC5_AKKM8 Unreviewed; 542 AA.
AC B2UPC5;
DT 01-JUL-2008, integrated into UniProtKB/TrEMBL.
DT 01-JUL-2008, sequence version 1.
DT 27-MAR-2024, entry version 77.
DE SubName: Full=Sulfatase {ECO:0000313|EMBL:ACD04402.1};
GN OrderedLocusNames=Amuc_0565 {ECO:0000313|EMBL:ACD04402.1};
OS Akkermansia muciniphila (strain ATCC BAA-835 / DSM 22959 / JCM 33894 / BCRC
OS 81048 / CCUG 64013 / CIP 107961 / Muc).
OC Bacteria; Verrucomicrobiota; Verrucomicrobiae; Verrucomicrobiales;
OC Akkermansiaceae; Akkermansia.
OX NCBI_TaxID=349741 {ECO:0000313|EMBL:ACD04402.1, ECO:0000313|Proteomes:UP000001031};
RN [1] {ECO:0000313|Proteomes:UP000001031}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-835 / DSM 22959 / JCM 33894 / BCRC 81048 / CCUG 64013
RC / CIP 107961 / Muc {ECO:0000313|Proteomes:UP000001031};
RX PubMed=21390229; DOI=10.1371/journal.pone.0016876;
RA van Passel M.W., Kant R., Zoetendal E.G., Plugge C.M., Derrien M.,
RA Malfatti S.A., Chain P.S., Woyke T., Palva A., de Vos W.M., Smidt H.;
RT "The genome of Akkermansia muciniphila, a dedicated intestinal mucin
RT degrader, and its use in exploring intestinal metagenomes.";
RL PLoS ONE 6:E16876-E16876(2011).
CC -!- SIMILARITY: Belongs to the sulfatase family.
CC {ECO:0000256|ARBA:ARBA00008779}.
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DR EMBL; CP001071; ACD04402.1; -; Genomic_DNA.
DR RefSeq; WP_012419617.1; NC_010655.1.
DR AlphaFoldDB; B2UPC5; -.
DR SMR; B2UPC5; -.
DR STRING; 349741.Amuc_0565; -.
DR PaxDb; 349741-Amuc_0565; -.
DR KEGG; amu:Amuc_0565; -.
DR eggNOG; COG3119; Bacteria.
DR HOGENOM; CLU_006332_11_1_0; -.
DR OrthoDB; 9762324at2; -.
DR BioCyc; AMUC349741:G1GBX-620-MONOMER; -.
DR Proteomes; UP000001031; Chromosome.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd16025; PAS_like; 1.
DR Gene3D; 3.30.1120.10; -; 1.
DR Gene3D; 3.40.720.10; Alkaline Phosphatase, subunit A; 1.
DR InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR InterPro; IPR024607; Sulfatase_CS.
DR InterPro; IPR000917; Sulfatase_N.
DR PANTHER; PTHR42693:SF33; ARYLSULFATASE; 1.
DR PANTHER; PTHR42693; ARYLSULFATASE FAMILY MEMBER; 1.
DR Pfam; PF00884; Sulfatase; 1.
DR SUPFAM; SSF53649; Alkaline phosphatase-like; 1.
DR PROSITE; PS00149; SULFATASE_2; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000001031}.
FT DOMAIN 35..425
FT /note="Sulfatase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00884"
SQ SEQUENCE 542 AA; 60718 MW; 4623D2B8F32A3229 CRC64;
MIFHIPFMCS TLRSSIMSSI AFWLLTLVPS LADRPNIVLI LADDMGWSDP GCYGSEIPTP
ALDTLARQGM LATRLYTASR CSPSRASIMT GCEPHKVDVG LLDDDSGRPG YRGRLNPGIP
TLPELLKKAG YRTYLSGKWH LGKVRGSYPW DRGFDRSRGL LGGAADYYRP MPDSPFGENG
KLLRPEDLPE DFYMTDDITK TALAYIGDAA KSRQPFFLYV AYTAPHTPLQ APRREIEKML
PFYNGKSPHA IASKRLEKQK LLGIVPPAAK LGMAGKFNPE GYEKTSAKRK DYIAECMATY
AAQIVIMDRG IGRILASLER HRLSDNTIVM FLSDNGATAE MPQNNKNKKT TLPTGPLGEV
GCRDGYGPMW AAVSNTPYRQ YKIETFDGGL SAPFIIRYPS KIRPGSRYHS PFLLQDIAPT
CLAWAALPIP AHMDGKPLNT YWNNPPELPP SKVWDFIPNT CPPRTIFWEH QRNRAALTSQ
FKLVAPNRGP WQVYDIRDRT EQNNLASRHQ TLVEQLSAQY RKWAAENHAE RHSPAEKRAY
AP
//
