ID B2UPK6_AKKM8 Unreviewed; 285 AA.
AC B2UPK6;
DT 01-JUL-2008, integrated into UniProtKB/TrEMBL.
DT 01-JUL-2008, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE RecName: Full=Ig protease IdeS domain-containing protein {ECO:0000259|Pfam:PF09028};
GN OrderedLocusNames=Amuc_0646 {ECO:0000313|EMBL:ACD04483.1};
OS Akkermansia muciniphila (strain ATCC BAA-835 / DSM 22959 / JCM 33894 / BCRC
OS 81048 / CCUG 64013 / CIP 107961 / Muc).
OC Bacteria; Verrucomicrobiota; Verrucomicrobiae; Verrucomicrobiales;
OC Akkermansiaceae; Akkermansia.
OX NCBI_TaxID=349741 {ECO:0000313|EMBL:ACD04483.1, ECO:0000313|Proteomes:UP000001031};
RN [1] {ECO:0000313|Proteomes:UP000001031}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-835 / DSM 22959 / JCM 33894 / BCRC 81048 / CCUG 64013
RC / CIP 107961 / Muc {ECO:0000313|Proteomes:UP000001031};
RX PubMed=21390229; DOI=10.1371/journal.pone.0016876;
RA van Passel M.W., Kant R., Zoetendal E.G., Plugge C.M., Derrien M.,
RA Malfatti S.A., Chain P.S., Woyke T., Palva A., de Vos W.M., Smidt H.;
RT "The genome of Akkermansia muciniphila, a dedicated intestinal mucin
RT degrader, and its use in exploring intestinal metagenomes.";
RL PLoS ONE 6:E16876-E16876(2011).
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DR EMBL; CP001071; ACD04483.1; -; Genomic_DNA.
DR RefSeq; WP_012419698.1; NZ_CP071807.1.
DR AlphaFoldDB; B2UPK6; -.
DR STRING; 349741.Amuc_0646; -.
DR PaxDb; 349741-Amuc_0646; -.
DR GeneID; 60880461; -.
DR KEGG; amu:Amuc_0646; -.
DR HOGENOM; CLU_812893_0_0_0; -.
DR OrthoDB; 1100299at2; -.
DR BioCyc; AMUC349741:G1GBX-704-MONOMER; -.
DR Proteomes; UP000001031; Chromosome.
DR GO; GO:0008233; F:peptidase activity; IEA:InterPro.
DR Gene3D; 3.90.70.10; Cysteine proteinases; 1.
DR InterPro; IPR015117; IdeS.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR013424; PEP_exosort_dom.
DR NCBIfam; TIGR02595; PEP_CTERM; 1.
DR Pfam; PF09028; Mac-1; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001031};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..285
FT /note="Ig protease IdeS domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002781273"
FT DOMAIN 166..221
FT /note="Ig protease IdeS"
FT /evidence="ECO:0000259|Pfam:PF09028"
SQ SEQUENCE 285 AA; 31672 MW; 71C70D41E016BE05 CRC64;
MLRTLSLFFL FALVPVQAAI YFAHNVSEDS GFINTKKYWN GDSDLCWAAT ASNMLQWWQN
NSSGIPAFVP NGQNESGRTE IYDVFCNNWA NTGKGIEIGL RWYLGGKPLN PNNYLYDFKE
TITEPQNTGR YWEGYITSLG LSSSTWEGDC PFISSKYFTQ SDFPLQFGTD LVSFFQNGGV
VGLSIAPASG PGHAITCWGI EVDDTTGMAK SLYVTDSDNG QGLEKRDVYY HETDGTLHLG
SENGPRINAY DALMLPFYNV PEPSTAVLTT LAAGTAFCRR RRRRS
//
