ID B2VJ38_ERWT9 Unreviewed; 206 AA.
AC B2VJ38;
DT 01-JUL-2008, integrated into UniProtKB/TrEMBL.
DT 01-JUL-2008, sequence version 1.
DT 27-MAR-2024, entry version 66.
DE RecName: Full=nicotinamidase {ECO:0000256|ARBA:ARBA00039017};
DE EC=3.5.1.19 {ECO:0000256|ARBA:ARBA00039017};
DE AltName: Full=Nicotinamide deamidase {ECO:0000256|ARBA:ARBA00043224};
GN Name=pncA {ECO:0000313|EMBL:CAO96609.1};
GN OrderedLocusNames=ETA_15630 {ECO:0000313|EMBL:CAO96609.1};
OS Erwinia tasmaniensis (strain DSM 17950 / CFBP 7177 / CIP 109463 / NCPPB
OS 4357 / Et1/99).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Erwiniaceae; Erwinia.
OX NCBI_TaxID=465817 {ECO:0000313|EMBL:CAO96609.1, ECO:0000313|Proteomes:UP000001726};
RN [1] {ECO:0000313|EMBL:CAO96609.1, ECO:0000313|Proteomes:UP000001726}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17950 / CFBP 7177 / CIP 109463 / NCPPB 4357 / Et1/99
RC {ECO:0000313|Proteomes:UP000001726};
RX PubMed=18462403; DOI=10.1111/j.1462-2920.2008.01639.x;
RA Kube M., Migdoll A.M., Mueller I., Kuhl H., Beck A., Reinhardt R.,
RA Geider K.;
RT "The genome of Erwinia tasmaniensis strain Et1/99, a non-pathogenic
RT bacterium in the genus Erwinia.";
RL Environ. Microbiol. 10:2211-2222(2008).
CC -!- PATHWAY: Cofactor biosynthesis; nicotinate biosynthesis; nicotinate
CC from nicotinamide: step 1/1. {ECO:0000256|ARBA:ARBA00037900}.
CC -!- SIMILARITY: Belongs to the isochorismatase family.
CC {ECO:0000256|ARBA:ARBA00006336}.
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DR EMBL; CU468135; CAO96609.1; -; Genomic_DNA.
DR AlphaFoldDB; B2VJ38; -.
DR STRING; 465817.ETA_15630; -.
DR KEGG; eta:ETA_15630; -.
DR eggNOG; COG1335; Bacteria.
DR HOGENOM; CLU_068979_13_1_6; -.
DR Proteomes; UP000001726; Chromosome.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0019363; P:pyridine nucleotide biosynthetic process; IEA:UniProtKB-KW.
DR CDD; cd01011; nicotinamidase; 1.
DR Gene3D; 3.40.50.850; Isochorismatase-like; 1.
DR InterPro; IPR000868; Isochorismatase-like.
DR InterPro; IPR036380; Isochorismatase-like_sf.
DR PANTHER; PTHR11080:SF2; LD05707P; 1.
DR PANTHER; PTHR11080; PYRAZINAMIDASE/NICOTINAMIDASE; 1.
DR Pfam; PF00857; Isochorismatase; 1.
DR SUPFAM; SSF52499; Isochorismatase-like hydrolases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:CAO96609.1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Pyridine nucleotide biosynthesis {ECO:0000256|ARBA:ARBA00022642};
KW Reference proteome {ECO:0000313|Proteomes:UP000001726}.
FT DOMAIN 8..205
FT /note="Isochorismatase-like"
FT /evidence="ECO:0000259|Pfam:PF00857"
SQ SEQUENCE 206 AA; 22130 MW; 73DAA24F8BFA1B77 CRC64;
MTMRGRQALL LIDLQNDFCS GGALAVREGE QTIAVANRLA AEFQQRGETV IATLDWHPAG
HGSFASSAGT TPGTLGQLHG LPQIWWPDHC VQHSDGAQLH PALDRAAIDL LVHKGENAEI
DSYSAFYDNG HRQQTVLDGW LKEHGVTALT IMGLATDYCV KFSVLDALAL GYQVTVVAEG
CRGVNLHPDD SRNALTDMVQ AGASLM
//
