ID B2VTE5_PYRTR Unreviewed; 1452 AA.
AC B2VTE5;
DT 01-JUL-2008, integrated into UniProtKB/TrEMBL.
DT 01-JUL-2008, sequence version 1.
DT 24-JAN-2024, entry version 48.
DE RecName: Full=Integrase catalytic domain-containing protein {ECO:0000259|PROSITE:PS50994};
GN ORFNames=PTRG_01909 {ECO:0000313|EMBL:EDU41347.1};
OS Pyrenophora tritici-repentis (strain Pt-1C-BFP) (Wheat tan spot fungus)
OS (Drechslera tritici-repentis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Pleosporomycetidae; Pleosporales; Pleosporineae; Pleosporaceae;
OC Pyrenophora.
OX NCBI_TaxID=426418 {ECO:0000313|EMBL:EDU41347.1, ECO:0000313|Proteomes:UP000001471};
RN [1] {ECO:0000313|Proteomes:UP000001471}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Pt-1C-BFP {ECO:0000313|Proteomes:UP000001471};
RX PubMed=23316438; DOI=10.1534/g3.112.004044;
RA Manning V.A., Pandelova I., Dhillon B., Wilhelm L.J., Goodwin S.B.,
RA Berlin A.M., Figueroa M., Freitag M., Hane J.K., Henrissat B., Holman W.H.,
RA Kodira C.D., Martin J., Oliver R.P., Robbertse B., Schackwitz W.,
RA Schwartz D.C., Spatafora J.W., Turgeon B.G., Yandava C., Young S., Zhou S.,
RA Zeng Q., Grigoriev I.V., Ma L.-J., Ciuffetti L.M.;
RT "Comparative genomics of a plant-pathogenic fungus, Pyrenophora tritici-
RT repentis, reveals transduplication and the impact of repeat elements on
RT pathogenicity and population divergence.";
RL G3 (Bethesda) 3:41-63(2013).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) =
CC diphosphate + DNA(n+1); Xref=Rhea:RHEA:22508, Rhea:RHEA-COMP:17339,
CC Rhea:RHEA-COMP:17340, ChEBI:CHEBI:33019, ChEBI:CHEBI:61560,
CC ChEBI:CHEBI:173112; EC=2.7.7.49;
CC Evidence={ECO:0000256|ARBA:ARBA00024557};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) =
CC diphosphate + DNA(n+1); Xref=Rhea:RHEA:22508, Rhea:RHEA-COMP:17339,
CC Rhea:RHEA-COMP:17340, ChEBI:CHEBI:33019, ChEBI:CHEBI:61560,
CC ChEBI:CHEBI:173112; EC=2.7.7.7;
CC Evidence={ECO:0000256|ARBA:ARBA00024632};
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DR EMBL; DS231615; EDU41347.1; -; Genomic_DNA.
DR RefSeq; XP_001932242.1; XM_001932207.1.
DR STRING; 426418.B2VTE5; -.
DR EnsemblFungi; EDU41347; EDU41347; PTRG_01909.
DR GeneID; 6338475; -.
DR eggNOG; KOG0017; Eukaryota.
DR HOGENOM; CLU_002055_0_0_1; -.
DR InParanoid; B2VTE5; -.
DR OrthoDB; 2554338at2759; -.
DR Proteomes; UP000001471; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProt.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-EC.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003964; F:RNA-directed DNA polymerase activity; IEA:UniProtKB-EC.
DR GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR GO; GO:0032196; P:transposition; IEA:UniProtKB-KW.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR001584; Integrase_cat-core.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR InterPro; IPR013103; RVT_2.
DR Pfam; PF07727; RVT_2; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS50994; INTEGRASE; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001471};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884};
KW Transposable element {ECO:0000256|ARBA:ARBA00022464};
KW Transposition {ECO:0000256|ARBA:ARBA00022578}.
FT DOMAIN 680..848
FT /note="Integrase catalytic"
FT /evidence="ECO:0000259|PROSITE:PS50994"
FT REGION 357..377
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 958..1012
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1452 AA; 164177 MW; 97EF7FC52E4258B8 CRC64;
MWEDNVEAPD DEVGITTATT YIARAIADYT DRPTADEELF WEFRQDFEGW TEAMFLRAQP
IYTKELKRIL RFKGVYTGRI NMAPTYQRVQ SQQPPLTYNN FDRFREYTPA YPQRPKGLSV
PPIVPSGETD PYKAVPPIEF GNEKLDPKTI NVFVKMWDRD KKYTGKPYDL LDDKLKIFYS
ICYHADIEPG QFHAVFPRIL DGRAEEYYLH FVDQRMDTFL TAYTKLKNHF DTDVNHGHYY
ADWTTTSFVK VRRENPEKNL HEVLDIMLDK LQLCQRALGQ QYMGEYALRT TVITACRGVK
ELEMALYKPS LECEVLFGDL RSSIENSLAM TVSVNFTEAD TDSQYYLDRR YNNNSSGRLR
GNYNPRGGRS GFTRGRGGLQ HRSGVNTQID KKCYVCGKTG CWSTNHTLEE RKRSKAQYIT
HCAITGEQME FSTFLVAYEG EEVDQFFLEE QDEDDEDQRL AVKYLTDQAF LHHVTGEDVY
RCKEPITPAT QFLIEDRYSR ITYQGILPDT GASNVSTAGK EQFWALQTED PTVTLDTSTA
GNASVQFGKG SVTTSIGTAH VSTQIGKIKF EVLNAPTPFL LCLKDMDRLH VYFNNTTDQL
VQGKATFPVI RKWGHPWFHL SKAERARVFL TETELRRLHR RFGHPAVERL IRLLKRAGHE
DVDERLLREI QTFCHHCQAH DPAPRRFKFR LKDDREFNFE ILVDVMYLSG KPVLHVIDSA
TTFNGARFLP SMSAKDTWEA LRLLWIDTYQ GPPDIVTHDA GTNFASVEFR SEAKIMGITC
KQVPTEAHWS IGKVERYHAP LRRVYEILRT ELDTGTSDAA VLQMAVKAVN DTAGPDGLVP
TLLVFGAYPR ISMDSPPSPS ITHRAEAIQK AMRALRKASA EHAVSNALGT RNGPTTDGVL
SLPLQSEVMV WREKNGWQGP YRVIDMKDHD VTVDMINGPT TFRSTVVKPY YRDLTTAIDG
ADQGTGGSPT TDEAIADEPP LPVPPAEANQ AAQPRKRGRP PGSKNKPKVQ YLSKKEEDDY
ALAVKLRNDG VINVPGAPFE ASDQKEIDDL VGRGVFSFEL FDPTLHGGYR IFKSRMVREV
KGKTMVPYEK SRLVVQGYND EGKHEILTQS PTIQRASQRL ILALAPALLD EGMVVELRDI
TQAYPQAQTE LFRTVLAHLP KELITKYPEG TIIRVIKPLY GIAEAGVHWF ATYQGHHCKE
LDMATSTYDP CLLITNGRRE AFGIVGLQTD DTLAIGTPAF SGAEDAALQK ANFRAKPKER
LSKEVSLEFN GCTLTLRGDT ILLTQKGQGA KIEIIDPKAA NRAQKYMEQR ARGAYIASIC
QPEASFDLSA AAQIQQPKDT EYVKLNRRLQ WQSESIQRGL RYVPLDLATA KLVVFTDGSF
ANNQDLSSQL GYLLILANES SRQDSTFDIR GNVIHWSSTK CKRVTRSVLA SETTPRSTTD
PTYCVYGFIL LV
//
