ID   B2W7P8_PYRTR            Unreviewed;       740 AA.
AC   B2W7P8;
DT   01-JUL-2008, integrated into UniProtKB/TrEMBL.
DT   01-JUL-2008, sequence version 1.
DT   24-JAN-2024, entry version 60.
DE   SubName: Full=XPG N-terminal domain containing protein {ECO:0000313|EMBL:EDU48756.1};
GN   ORFNames=PTRG_05836 {ECO:0000313|EMBL:EDU48756.1};
OS   Pyrenophora tritici-repentis (strain Pt-1C-BFP) (Wheat tan spot fungus)
OS   (Drechslera tritici-repentis).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC   Pleosporomycetidae; Pleosporales; Pleosporineae; Pleosporaceae;
OC   Pyrenophora.
OX   NCBI_TaxID=426418 {ECO:0000313|EMBL:EDU48756.1, ECO:0000313|Proteomes:UP000001471};
RN   [1] {ECO:0000313|Proteomes:UP000001471}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Pt-1C-BFP {ECO:0000313|Proteomes:UP000001471};
RX   PubMed=23316438; DOI=10.1534/g3.112.004044;
RA   Manning V.A., Pandelova I., Dhillon B., Wilhelm L.J., Goodwin S.B.,
RA   Berlin A.M., Figueroa M., Freitag M., Hane J.K., Henrissat B., Holman W.H.,
RA   Kodira C.D., Martin J., Oliver R.P., Robbertse B., Schackwitz W.,
RA   Schwartz D.C., Spatafora J.W., Turgeon B.G., Yandava C., Young S., Zhou S.,
RA   Zeng Q., Grigoriev I.V., Ma L.-J., Ciuffetti L.M.;
RT   "Comparative genomics of a plant-pathogenic fungus, Pyrenophora tritici-
RT   repentis, reveals transduplication and the impact of repeat elements on
RT   pathogenicity and population divergence.";
RL   G3 (Bethesda) 3:41-63(2013).
CC   -!- SIMILARITY: Belongs to the XPG/RAD2 endonuclease family.
CC       {ECO:0000256|ARBA:ARBA00024023}.
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DR   EMBL; DS231619; EDU48756.1; -; Genomic_DNA.
DR   RefSeq; XP_001936169.1; XM_001936134.1.
DR   AlphaFoldDB; B2W7P8; -.
DR   STRING; 426418.B2W7P8; -.
DR   EnsemblFungi; EDU48756; EDU48756; PTRG_05836.
DR   GeneID; 6344090; -.
DR   eggNOG; ENOG502QVHA; Eukaryota.
DR   HOGENOM; CLU_378548_0_0_1; -.
DR   InParanoid; B2W7P8; -.
DR   OMA; FYQTKVI; -.
DR   OrthoDB; 6876at2759; -.
DR   Proteomes; UP000001471; Unassembled WGS sequence.
DR   GO; GO:0004518; F:nuclease activity; IEA:InterPro.
DR   GO; GO:0006974; P:DNA damage response; IEA:UniProt.
DR   GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR   CDD; cd09902; H3TH_MKT1; 1.
DR   CDD; cd09858; PIN_MKT1; 1.
DR   Gene3D; 3.40.50.1010; 5'-nuclease; 1.
DR   InterPro; IPR022039; MKT1_C.
DR   InterPro; IPR037314; MKT1_H3TH.
DR   InterPro; IPR022040; MKT1_N.
DR   InterPro; IPR029060; PIN-like_dom_sf.
DR   InterPro; IPR006086; XPG-I_dom.
DR   InterPro; IPR006084; XPG/Rad2.
DR   PANTHER; PTHR11081; FLAP ENDONUCLEASE FAMILY MEMBER; 1.
DR   PANTHER; PTHR11081:SF32; POST-TRANSCRIPTIONAL REGULATOR MKT1; 1.
DR   Pfam; PF12246; MKT1_C; 1.
DR   Pfam; PF12247; MKT1_N; 1.
DR   Pfam; PF00867; XPG_I; 1.
DR   SMART; SM00484; XPGI; 1.
DR   SUPFAM; SSF88723; PIN domain-like; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000001471};
KW   Translation regulation {ECO:0000256|ARBA:ARBA00022845}.
FT   DOMAIN          142..210
FT                   /note="XPG-I"
FT                   /evidence="ECO:0000259|SMART:SM00484"
SQ   SEQUENCE   740 AA;  82488 MW;  0D8342DA793C1AFC CRC64;
     MIRDFVQWTA AIVEQGDLTE LRSSRVGIEA ADYLNQRILN HPRAKEPLVP ALGGLPLALT
     QHIEEDLATF RSHEIEPYFI FSGLDLTKQG NPFGQKTAEA TVNADAWNLY DSHQAEASVA
     KFGESTYVTP EDLFRALQSI LTKQNVRWQV APYSAWAQLA YCEKNEYVHA VAGSSDLLIF
     ECAKVITSWD FEARQFSFIR REKCVADLSK FVGASTVTDD IFLDTCLLAG TPFLPTLPIL
     DAPNRADLLK PHSAIKMIMN TTGQSGFSVV VSNNDVPPSG KEYVTRYQKA RLAVKNHPVY
     TEEGKVEPQN SASMPNDAGQ YLGQRLPDEI LHYMSRGLIN ARILQWRTTC EVFEVPPMDG
     GESPEYRNLV SVKLIPLRTA AINLLSSSLH NWYRHKPLEQ TNWFSITEPT RKSASTTIHV
     ERPSEAQSPS IVDTWNVKEA VFKDAIGQYK DADFVSKTIA KKNPKNPLST APEILYNSIW
     RFLALREYVD VKTHSLTQWG KVLAAVISGL KGKAEHEAAV LAVELIRMGL LISDINMFPT
     YNGAPMRGSS EYIGQTQARM TDNSTAKDKN ANMLVSRVAG LGILHHRPIG FTGPLSQHLL
     GYNSIINVVR QTLRDLVEVA ATHMFATGCC NRHADISAIA MQLPFLLPNN CALSIAVKSY
     LDELLSNDAD PTSPETKARV VDTASMRYFP QSLQFETDLK MAFSLWDAIY AGVNSANNTT
     IPEATKQIWT ETDKWLSERR
//