ID B2WCL1_PYRTR Unreviewed; 535 AA.
AC B2WCL1;
DT 01-JUL-2008, integrated into UniProtKB/TrEMBL.
DT 01-JUL-2008, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE RecName: Full=Major facilitator superfamily (MFS) profile domain-containing protein {ECO:0000259|PROSITE:PS50850};
GN ORFNames=PTRG_07720 {ECO:0000313|EMBL:EDU50639.1};
OS Pyrenophora tritici-repentis (strain Pt-1C-BFP) (Wheat tan spot fungus)
OS (Drechslera tritici-repentis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Pleosporomycetidae; Pleosporales; Pleosporineae; Pleosporaceae;
OC Pyrenophora.
OX NCBI_TaxID=426418 {ECO:0000313|EMBL:EDU50639.1, ECO:0000313|Proteomes:UP000001471};
RN [1] {ECO:0000313|Proteomes:UP000001471}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Pt-1C-BFP {ECO:0000313|Proteomes:UP000001471};
RX PubMed=23316438; DOI=10.1534/g3.112.004044;
RA Manning V.A., Pandelova I., Dhillon B., Wilhelm L.J., Goodwin S.B.,
RA Berlin A.M., Figueroa M., Freitag M., Hane J.K., Henrissat B., Holman W.H.,
RA Kodira C.D., Martin J., Oliver R.P., Robbertse B., Schackwitz W.,
RA Schwartz D.C., Spatafora J.W., Turgeon B.G., Yandava C., Young S., Zhou S.,
RA Zeng Q., Grigoriev I.V., Ma L.-J., Ciuffetti L.M.;
RT "Comparative genomics of a plant-pathogenic fungus, Pyrenophora tritici-
RT repentis, reveals transduplication and the impact of repeat elements on
RT pathogenicity and population divergence.";
RL G3 (Bethesda) 3:41-63(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; DS231622; EDU50639.1; -; Genomic_DNA.
DR RefSeq; XP_001938052.1; XM_001938017.1.
DR AlphaFoldDB; B2WCL1; -.
DR STRING; 426418.B2WCL1; -.
DR EnsemblFungi; EDU50639; EDU50639; PTRG_07720.
DR GeneID; 6345993; -.
DR eggNOG; KOG0255; Eukaryota.
DR HOGENOM; CLU_008455_8_4_1; -.
DR InParanoid; B2WCL1; -.
DR OMA; MNPGWAF; -.
DR OrthoDB; 1701613at2759; -.
DR Proteomes; UP000001471; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR Gene3D; 1.20.1720.10; Multidrug resistance protein D; 1.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR23502; MAJOR FACILITATOR SUPERFAMILY; 1.
DR PANTHER; PTHR23502:SF51; QUINIDINE RESISTANCE PROTEIN 1-RELATED; 1.
DR Pfam; PF07690; MFS_1; 1.
DR PRINTS; PR01036; TCRTETB.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50850; MFS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001471};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 57..78
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 98..116
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 123..141
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 147..170
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 182..207
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 213..232
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 300..319
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 331..355
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 390..408
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 420..441
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 453..473
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 479..501
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 58..505
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
FT REGION 1..28
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 514..535
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 7..28
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 535 AA; 58594 MW; E59987FB4A0C9636 CRC64;
MASTRDAASE EHVDLNSEKE RGEEADVDVE RVGVQPGLQR TLSEPPYSVF SKGMKTWIIF
LVSISSLISP FGASMFLPAL NVLSDVLHIT PSQVNISITT YMIAQAIAPA FLGTLSDNSG
RRLTFIICFV IYSIGNIGLA LQTNYTALLI LRMLQAVGGT AAIALTMAVV ADISTSAERG
TYMGYAQAGI LMGPAFGPAI GGLLAQYLGW RSIFWFLAIF SGVLLVLFVF LFPETCRKVV
GNGSIPPQGV NRSVISCIQQ RKLAKLSPDE ISTKPEKKKI AWPNPLATFR ILAEKESGIL
LMYNGLFFTG MMVTVSAIPT LFYEAYGLDE LHIGLCYISN GVAALVSSLT MGRVVDWNFR
RYARAIGMTI TKGKQQDLSN FPLERVRLQI LIPGHILGMF GLVMFGWTLK FRTHIVGPEI
ALFVMGFGVT TAFNITNGLL IDLHRDQPAA ATAAVNFARC FMSAGGTAAI IPMCHAMNPG
WAFTFIAFIY VILLGVVLWV MRNGMKWRQK LAEKKKLQSE AKEKEKEARE EAART
//
