ID B2XRL4_CHLTH Unreviewed; 275 AA.
AC B2XRL4;
DT 01-JUL-2008, integrated into UniProtKB/TrEMBL.
DT 01-JUL-2008, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=phospholipase D {ECO:0000256|ARBA:ARBA00012027};
DE EC=3.1.4.4 {ECO:0000256|ARBA:ARBA00012027};
OS Chlamydia trachomatis.
OC Bacteria; Chlamydiota; Chlamydiia; Chlamydiales; Chlamydiaceae;
OC Chlamydia/Chlamydophila group; Chlamydia.
OX NCBI_TaxID=813 {ECO:0000313|EMBL:ABX82350.1};
RN [1] {ECO:0000313|EMBL:ABX82350.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=C/TW-3 {ECO:0000313|EMBL:ABX82350.1};
RX PubMed=18199030; DOI=10.1086/525285;
RA Kari L., Whitmire W.M., Carlson J.H., Crane D.D., Reveneau N., Nelson D.E.,
RA Mabey D.C., Bailey R.L., Holland M.J., McClarty G., Caldwell H.D.;
RT "Pathogenic diversity among Chlamydia trachomatis ocular strains in
RT nonhuman primates is affected by subtle genomic variations.";
RL J. Infect. Dis. 197:449-456(2008).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 1,2-diacyl-
CC sn-glycero-3-phosphate + choline + H(+); Xref=Rhea:RHEA:14445,
CC ChEBI:CHEBI:15354, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:57643, ChEBI:CHEBI:58608; EC=3.1.4.4;
CC Evidence={ECO:0000256|ARBA:ARBA00000798};
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DR EMBL; EU121606; ABX82350.1; -; Genomic_DNA.
DR AlphaFoldDB; B2XRL4; -.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0006793; P:phosphorus metabolic process; IEA:UniProt.
DR CDD; cd09116; PLDc_Nuc_like; 1.
DR Gene3D; 3.30.870.10; Endonuclease Chain A; 2.
DR InterPro; IPR025202; PLD-like_dom.
DR InterPro; IPR001736; PLipase_D/transphosphatidylase.
DR PANTHER; PTHR43856; CARDIOLIPIN HYDROLASE; 1.
DR PANTHER; PTHR43856:SF1; MITOCHONDRIAL CARDIOLIPIN HYDROLASE; 1.
DR Pfam; PF13091; PLDc_2; 2.
DR SMART; SM00155; PLDc; 2.
DR SUPFAM; SSF56024; Phospholipase D/nuclease; 2.
DR PROSITE; PS50035; PLD; 2.
PE 4: Predicted;
FT DOMAIN 70..93
FT /note="PLD phosphodiesterase"
FT /evidence="ECO:0000259|PROSITE:PS50035"
FT DOMAIN 212..239
FT /note="PLD phosphodiesterase"
FT /evidence="ECO:0000259|PROSITE:PS50035"
SQ SEQUENCE 275 AA; 30958 MW; CEA1080708DB4237 CRC64;
MLCDAILQAN RIITMRIFNI GSPEIIRALI QAVRRNIPVV VSAWNFPNLS NWDRKSELCV
ELRGNPQICL HKKTTLIDNQ LAIIGTANYT KSSFFKDINL TALIQNPALY SLILRGTRGS
VSIGSQTISY YPLPFPQSNT KTLPIIQEIQ KAQRTIKIAM SIFSHPEIFL ALEQAHLRGV
TITIVINKKE SAHTLDILHR ISALLLLKSV TTVDSLHAKI CLIDDQTLIF GSPNWTYHGM
HKNLEDLLIV TPLTPKQIYS IQEIWAFLLK NSSPV
//
