ID B3DTD7_BIFLD Unreviewed; 837 AA.
AC B3DTD7;
DT 22-JUL-2008, integrated into UniProtKB/TrEMBL.
DT 22-JUL-2008, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE SubName: Full=Transglutaminase-like cysteine protease {ECO:0000313|EMBL:ACD98406.1};
GN OrderedLocusNames=BLD_0960 {ECO:0000313|EMBL:ACD98406.1};
OS Bifidobacterium longum (strain DJO10A).
OC Bacteria; Actinomycetota; Actinomycetes; Bifidobacteriales;
OC Bifidobacteriaceae; Bifidobacterium.
OX NCBI_TaxID=205913 {ECO:0000313|EMBL:ACD98406.1, ECO:0000313|Proteomes:UP000002419};
RN [1] {ECO:0000313|EMBL:ACD98406.1, ECO:0000313|Proteomes:UP000002419}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DJO10A {ECO:0000313|EMBL:ACD98406.1,
RC ECO:0000313|Proteomes:UP000002419};
RX PubMed=16391088; DOI=10.1128/AEM.72.1.527-535.2006;
RA Lee J.H., O'Sullivan D.J.;
RT "Sequence analysis of two cryptic plasmids from Bifidobacterium longum
RT DJO10A and construction of a shuttle cloning vector.";
RL Appl. Environ. Microbiol. 72:527-535(2006).
RN [2] {ECO:0000313|EMBL:ACD98406.1, ECO:0000313|Proteomes:UP000002419}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DJO10A {ECO:0000313|EMBL:ACD98406.1,
RC ECO:0000313|Proteomes:UP000002419};
RX PubMed=18505588; DOI=10.1186/1471-2164-9-247;
RA Lee J.H., Karamychev V.N., Kozyavkin S.A., Mills D., Pavlov A.R.,
RA Pavlova N.V., Polouchine N.N., Richardson P.M., Shakhova V.V.,
RA Slesarev A.I., Weimer B., O'Sullivan D.J.;
RT "Comparative genomic analysis of the gut bacterium Bifidobacterium longum
RT reveals loci susceptible to deletion during pure culture growth.";
RL BMC Genomics 9:247-247(2008).
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DR EMBL; CP000605; ACD98406.1; -; Genomic_DNA.
DR RefSeq; WP_010080838.1; NZ_AABM02000002.1.
DR AlphaFoldDB; B3DTD7; -.
DR KEGG; blj:BLD_0960; -.
DR HOGENOM; CLU_012121_2_0_11; -.
DR Proteomes; UP000002419; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 3.10.620.30; -; 1.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR002931; Transglutaminase-like.
DR PANTHER; PTHR42736; PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE; 1.
DR PANTHER; PTHR42736:SF1; PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE; 1.
DR Pfam; PF01841; Transglut_core; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:ACD98406.1};
KW Membrane {ECO:0000256|SAM:Phobius}; Protease {ECO:0000313|EMBL:ACD98406.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 71..89
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 95..116
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 123..144
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 185..205
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 211..231
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 238..256
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 262..285
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 678..698
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 474..608
FT /note="Transglutaminase-like"
FT /evidence="ECO:0000259|Pfam:PF01841"
FT REGION 612..659
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 817..837
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 644..659
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 822..837
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 837 AA; 89909 MW; EE2A1DDAFFE92DE6 CRC64;
MTFDQSSITN TNTAAYAGSS GTYTGTSSGT YTGTSTTTGS WADSTHSVIW MTRGNVLRGM
GLSRQPWGKR IASLVLIAAM MLLAQANLID VYGGVATWAI AAVPATLLGA IIALAGMLPA
LRLWWQIVFL AFAQFIIGPV VTLSSTTSHY VIPTLKTLSS GWEMTFGSFK YIISVDPPLG
TQDGVLMAVW TIGLWLTFLT GVFAINANAW LSLVGVLPLA AAVAVCALLG TDSGWQRAIC
GIAFALLLII WLSWRLELLE WGRWISALII VVLAAGLAFG GTLLVPQDRF VLRDRYDPPL
SPYDYTSPLS GMRSYIKDHK KDVLLTVHNL PAGTPVKLAV MDRFDGTVWN LSDSSEATDS
SNYHRVGTTI KADEQGKSFT ATFTVDQGLT DTWLPLAGAA TGVSFANDAD NGNDTFYYNT
DTDSAIIPAG TRKGLTYTES GIIARKPTDK QISSAAAARI TQPEAQDVPD SASKLATSIA
GGQSSGGAAA TALADTLKDS GWFSHGLEGD YPSDAGHGNY RINKLLAGTA MVGDSEQYAS
AMALMARDLG LPSRVVLGFL PKNEDGEITD ARTEKTSGNG TKIEFTGNDV TAWVEIKLQG
LGWVAFYPTP KETKMPDENQ NLTPPNPQTL VRQPPVPLTD PLRDQTQAKG QSSLAGADAD
DSPTNLFWVR FWRVTRKVAL YGSPLWTLLI ACGLILMFKA ILLARARRHG SPKTRVAAGW
NAIRMLAEQS GITAKGTRRD QAGAIARQLG TDDQALIQLG READYATFSG QDIESGQATT
YWTGVDQLRK AMLASLPRFR RIRTRLSLKS VAILSNGHAA KPHTTHVKRT RKKGKAS
//
